A5026383100- Neural dynamics and brain function
- Visual perception and processing mechanisms
- Functional Brain Connectivity Studies
- EEG and Brain-Computer Interfaces
- Action Observation and Synchronization
- Motor Control and Adaptation
- Neuroscience and Neural Engineering
- Neural and Behavioral Psychology Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Intensive Care Unit Cognitive Disorders
- Long-Term Effects of COVID-19
- Advanced Neuroimaging Techniques and Applications
- Memory and Neural Mechanisms
- Child and Animal Learning Development
- Advanced MRI Techniques and Applications
- Photoreceptor and optogenetics research
Clinique Romande de Réadaptation
2020-2025
École Polytechnique Fédérale de Lausanne
2019-2025
National Institute of Neurological Disorders and Stroke
2023-2025
Office of the Director
2024
National Institutes of Health
2023
Wyss Center for Bio and Neuroengineering
2020-2022
Hôpital du Valais
2021
Activities of daily living rely on our ability to acquire new motor skills composed precise action sequences. Early learning a sequential skill is characterized by steep performance improvements that develop predominantly during rest intervals interspersed with practice, form rapid consolidation. Here, we ask if the millisecond level neural representation an performed at different locations within sequence contextually differentiates or remains stable as evolves. Optimization machine...
Abstract With the increase in life expectancy and rapid evolution of daily technologies, older adults must constantly learn new skills to adapt society. Sleep reinforces acquired during day is associated with occurrence specific oscillations such as spindles. However, age, spindles deteriorate thus likely contribute memory impairments observed adults. The application electric currents by means transcranial alternating current stimulation (tACS) spindle-like waveform, applied night, was found...
Visual motion discrimination involves reciprocal interactions in the alpha band between primary visual cortex (V1) and mediotemporal areas (V5/MT). We investigated whether modulating phase synchronization using individualized multisite transcranial alternating current stimulation (tACS) over V5 V1 regions would improve discrimination. tested 3 groups of healthy subjects with following conditions: (1) In-Phase V1alpha-V5alpha tACS (0° lag), (2) Anti-Phase (180° lag) (3) sham tACS. Motion EEG...
At least 15% of patients who recover from acute severe respiratory syndrome coronavirus 2 infection experience lasting symptoms ("Long-COVID") including "brain fog" and deficits in declarative memory. It is not known if Long-COVID affects patients' ability to form retain procedural motor skill memories. The objective was determine the with acquire consolidate a new over training days. primary outcome difference early learning, measured as increase correct sequence typing speed initial 11...
Discrimination and integration of motion direction requires the interplay multiple brain areas. Theoretical accounts perception suggest that stimulus-related (i.e., exogenous) decision-related endogenous) factors affect distributed neuronal processing at different levels visual hierarchy. To test these predictions, we measured activity healthy participants during a discrimination task, using electroencephalography (EEG) functional magnetic resonance imaging (fMRI). We independently modeled...
ABSTRACT Visual motion discrimination involves reciprocal interactions in the alpha band between primary visual cortex (V1) and mediotemporal area (V5/MT). We investigated whether modulating phase synchronization using individualized multisite transcranial alternating current stimulation (tACS) over V5 V1 regions would improve discrimination. tested 3 groups of healthy subjects: 1) an In-Phase -V5 tACS (0° lag) group, 2) Anti-Phase (180° group 3) a sham group. Motion EEG activity were...
Background: Phase synchronization over long distances underlies inter-areal communication and importantly, modulates the flow of information processing to adjust cognitive demands.Objective: This study investigates impact single-session, cross-frequency (Alpha-Gamma) bifocal transcranial alternating current stimulation (cf-tACS) cortical visual motion network on coupling between primary cortex (V1) medio-temporal area (MT) direction discrimination.Methods: Based well-established...
Abstract Activities of daily living rely on our ability to acquire new motor skills composed precise action sequences. Early learning a sequential skill is characterized by steep performance improvements that develop predominantly during rest intervals interspersed with practice, form rapid consolidation. Here, we ask if the millisecond level neural representation an performed at different locations within sequence contextually differentiates or remains stable as evolves. Optimization...
Activities of daily living rely on our ability to acquire new motor skills composed precise action sequences. Early learning a sequential skill is characterized by steep performance improvements that develop predominantly during rest intervals interspersed with practice, form rapid consolidation. Here, we ask if the millisecond level neural representation an performed at different locations within sequence contextually differentiates or remains stable as evolves. Optimization machine...
Activities of daily living rely on our ability to acquire new motor skills composed precise action sequences. Early learning a sequential skill is characterized by steep performance improvements that develop predominantly during rest intervals interspersed with practice, form rapid consolidation. Here, we ask if the millisecond level neural representation an performed at different locations within sequence contextually differentiates or remains stable as evolves. Optimization machine...
Abstract Early skill learning develops in the context of activity changes distributed cortico-subcortical regions. Here, we investigated network hubs—centers information integration and transmission—within brain supporting early learning. We recorded magnetoencephalographic (MEG) healthy human subjects who learned a moderately difficult sequence with their non-dominant left hand. then computed hub strength by summing top 10% functional connectivity over 86 parcellated regions (AAL3 atlas)...
Abstract Understanding the causal relationship between a focal lesion and network (re)organization is crucial to accurately predict resulting large-scale symptoms of lesion. In this study, we applied short trains 10 Hz TMS healthy participants over early visual areas (EVA) or medio-temporal area (hMT+/MT) during motion discrimination task at rest, while concurrent fMRI was acquired. in stage processing induced specific deficit judging direction both sites, global perception preserved. This...