Chang-Hyun Park

ORCID: 0000-0001-5575-1467
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About
Contact & Profiles
Research Areas
  • Functional Brain Connectivity Studies
  • Advanced Neuroimaging Techniques and Applications
  • Transcranial Magnetic Stimulation Studies
  • Stroke Rehabilitation and Recovery
  • Advanced MRI Techniques and Applications
  • Face and Expression Recognition
  • Emotion and Mood Recognition
  • Ocular Surface and Contact Lens
  • Botulinum Toxin and Related Neurological Disorders
  • Neural dynamics and brain function
  • Glaucoma and retinal disorders
  • Educational Systems and Policies
  • Epilepsy research and treatment
  • Impact of Technology on Adolescents
  • Education and Learning Interventions
  • Corneal Surgery and Treatments
  • EEG and Brain-Computer Interfaces
  • Musculoskeletal pain and rehabilitation
  • Educational Research and Pedagogy
  • Neurological disorders and treatments
  • Motor Control and Adaptation
  • Vestibular and auditory disorders
  • Firm Innovation and Growth
  • Intraocular Surgery and Lenses
  • Neural Networks and Applications

Ewha Womans University
2016-2025

Severance Hospital
2019-2025

Yonsei University
2020-2025

École Polytechnique Fédérale de Lausanne
2018-2025

Clinique Romande de Réadaptation
2020-2025

Asan Medical Center
2019-2025

Pusan National University
2025

Pusan National University Hospital
2025

University of Ulsan
2025

Ulsan College
2025

Functional MRI (fMRI) studies could provide crucial information on the neural mechanisms of motor recovery in patients with stroke. Resting-state fMRI is applicable to stroke who are not capable proper performance task. In this study, we explored correlates by investigating longitudinal changes resting-state functional connectivity ipsilesional primary cortex (M1).A observational study using repeated experiments was conducted 12 data were acquired 4 times over a period 6 months. Patients...

10.1161/strokeaha.110.596155 article EN Stroke 2011-03-25

This work presents that Cu with atomic-scale spacings ( d s ) efficiently catalyses the electrochemical co-reduction of CO 2 and NO 3 − to urea. Specifically, near 6 Å (6 Å-Cu) produces urea a high yield rate partial current density.

10.1039/d3ee00008g article EN Energy & Environmental Science 2023-01-01

The stimulation of deep brain structures has thus far only been possible with invasive methods. Transcranial electrical temporal interference (tTIS) is a novel, noninvasive technology that might overcome this limitation. initial proof-of-concept was obtained through modeling, physics experiments and rodent models. Here we show successful neuromodulation the striatum via tTIS in humans using computational functional magnetic resonance imaging studies behavioral evaluations. Theta-burst...

10.1038/s41593-023-01457-7 article EN cc-by Nature Neuroscience 2023-10-19

Background and Purpose— Aside from the primary motor cortex, corticospinal tract (CST) also receives fibers dorsal ventral premotor cortices supplementary area, all of which might potentially contribute to function after stroke. We sought quantify microstructural integrity CST originating hand representations in these 4 separately examined how values related impairment. Methods— Probabilistic tractography functional MRI-defined cortical sites demonstrated continuous within each area a group...

10.1161/strokeaha.112.662619 article EN Stroke 2012-07-04

Stroke patients vary considerably in terms of outcomes: some present 'natural' recovery proportional to their initial impairment (fitters), while others do not (non-fitters). Thus, a key challenge stroke rehabilitation is identify individual potential make personalized decisions for neuro-rehabilitation, obviating the 'one-size-fits-all' approach. This goal requires (i) prediction courses acute stage; and (ii) an understanding underlying neuronal network mechanisms. 'Natural' especially...

10.1093/brain/awab082 article EN cc-by-nc Brain 2021-03-09

Background. This study aimed to delineate the cerebral attentional network in patients with traumatic brain injury (TBI) and assess for adaptations this response a rehabilitation intervention. Methods. Seventeen TBI 15 healthy subjects underwent functional magnetic resonance imaging (fMRI) using visuospatial attention task. Ten who successfully completed training had follow-up fMRI. Results. In patients, fMRI analysis showed more activation frontal temporoparietal lobes, as well less...

10.1177/1545968308328728 article EN Neurorehabilitation and neural repair 2008-12-31

Repetitive transcranial magnetic stimulation (rTMS) modulates central neuropathic pain in some patients after stroke, but the mechanisms of action are uncertain.. The authors used diffusion tensor imaging (DTI) and functional MRI (fMRI) to evaluate integrity thalamocortical tract (TCT) activation pattern network 22 with poststroke pain.Each patient underwent daily 10-Hz rTMS sessions for 1000 pulses on 5 consecutive days over hotspot first dorsal interosseus muscle. Pain severity was...

10.1177/1545968311423110 article EN Neurorehabilitation and neural repair 2011-10-06

Stroke results in reorganization of residual brain networks. The functional role regions within these networks remains unclear, particularly those the contralesional hemisphere. We studied 25 stroke patients with a range motor impairment and 23 healthy age-matched controls using magnetoencephalography (MEG) electromyography (EMG) to measure oscillatory signals from affected muscles simultaneously during simple isometric hand grip, which cortico-muscular coherence (CMC) was calculated. Peaks...

10.1016/j.nicl.2012.11.002 article EN cc-by NeuroImage Clinical 2012-11-13

<b>Background</b> The ability to predict outcome after stroke is clinically important for planning treatment and stratification in restorative clinical trials. In relation the upper limbs, main predictor of initial severity, with patients who present mild moderate impairment regaining about 70% their by 3 months post-stroke. However, those severe presentations, this proportional recovery applies only half, other half experiencing poor recovery. reasons failure recover are not established...

10.1136/jnnp-2016-315030 article EN cc-by Journal of Neurology Neurosurgery & Psychiatry 2017-06-22

Cerebrolysin is a neuropeptide preparation with neuroprotective and neurorestorative effects. Combining treatment standardized rehabilitation program may have potential synergistic effect in the subacute stage of stroke. This study aims to evaluate whether provides additional motor recovery on top therapy stroke patients moderate severe impairment.

10.1186/s12883-016-0553-z article EN cc-by BMC Neurology 2016-03-02

Background and purpose: Repetitive transcranial magnetic stimulation (rTMS) may enhance plastic changes in the human cortex modulation of behavior. However, underlying neural mechanisms have not been sufficiently investigated. We examined clinical effects correlates high-frequency rTMS coupled with motor training patients hemiparesis after stroke. Methods: Twenty-one were randomly divided into two groups, received either real or sham rTMS. Ten daily sessions 1,000 pulses applied at 10 Hz...

10.3233/rnn-2012-110162 article EN Restorative Neurology and Neuroscience 2012-01-01

The structural integrity of the corticospinal tract (CST) after stroke is closely linked to degree motor impairment. Simple and reliable methods assessing white matter within CST would facilitate use this measure in routine clinical practice. Commonly, diffusion tensor imaging used voxel-wise fractional anisotropy (FA) a variety regions interest (ROIs) representing CST. Several are currently with no consensus about which approach best. ROIs usually either whole or posterior limb internal...

10.1016/j.nicl.2013.04.002 article EN cc-by-nc-sa NeuroImage Clinical 2013-01-01

Brain activity during motor performance becomes more widespread and less lateralized with advancing age in response to ongoing degenerative processes. In this study, we were interested the mechanism by which change pattern of supports age. We used both transcranial magnetic stimulation (TMS) functional resonance imaging (fMRI) assess related changes system connectivity isometric hand grip. Paired pulse TMS was measure interhemispheric inhibition (IHI) from contralateral M1 (cM1) ipsilateral...

10.1016/j.neuroimage.2011.11.025 article EN cc-by NeuroImage 2011-11-19

Although a considerable number of patients suffer from cognitive impairments after stroke, the neural mechanism recovery has not yet been clarified. Repeated resting-state functional magnetic resonance imaging (fMRI) was used in this study to examine longitudinal changes default-mode network (DMN) during 6 months and investigate relationship between DMN recovery. Out 24 initially recruited right-hemispheric stroke patients, 11 (eight males, mean age 55.7 years) successfully completed...

10.1111/ejn.12640 article EN European Journal of Neuroscience 2014-06-16

Background Hippocampal atrophy is implicated in the early onset of Alzheimer's disease (AD). It closely associated with rapid cognitive decline and serves as a critical predictor for conversion from mild impairment (MCI) to AD. Consequently, growing interest utilizing hippocampal volume (HV) an outcome measure clinical trials, elucidating neurobiological mechanisms underlying essential diagnosing AD predicting its progression. Objective The risk apolipoprotein E ε4 ( APOE4) allele higher...

10.1177/13872877241313066 article EN other-oa Journal of Alzheimer s Disease 2025-02-09

Abstract With the increase in life expectancy and rapid evolution of daily technologies, older adults must constantly learn new skills to adapt society. Sleep reinforces acquired during day is associated with occurrence specific oscillations such as spindles. However, age, spindles deteriorate thus likely contribute memory impairments observed adults. The application electric currents by means transcranial alternating current stimulation (tACS) spindle-like waveform, applied night, was found...

10.1093/sleepadvances/zpaf022 article EN cc-by-nc-nd SLEEP Advances 2025-03-26

Nowadays, many researchers are interested in cognitive radio (CR) technology. We can say that the CR is extended technology of software defined radio. Both technologies seem to be similar but there an important difference. That a sensing and channel management function. always senses incumbent users (IU) (or primary users) appearing on has been used must evacuate from for preventing IU interferences. For this purpose, should include functionality being able find new relevant move. So,...

10.1109/apmc.2007.4554696 article EN Asia-Pacific Microwave Conference 2007-12-01
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