- Homotopy and Cohomology in Algebraic Topology
- Functional Brain Connectivity Studies
- Transcranial Magnetic Stimulation Studies
- Topological and Geometric Data Analysis
- Advanced Neuroimaging Techniques and Applications
- Algebraic structures and combinatorial models
- Stroke Rehabilitation and Recovery
- Geometric and Algebraic Topology
- Muscle activation and electromyography studies
- Advanced Topics in Algebra
- Advanced MRI Techniques and Applications
- EEG and Brain-Computer Interfaces
- Neurological disorders and treatments
- Structural Load-Bearing Analysis
- Geotechnical Engineering and Underground Structures
- Topic Modeling
- Neural and Behavioral Psychology Studies
- Landslides and related hazards
- Geotechnical Engineering and Analysis
- Advanced Differential Equations and Dynamical Systems
- Rock Mechanics and Modeling
- Structural Behavior of Reinforced Concrete
- Grouting, Rheology, and Soil Mechanics
- Semantic Web and Ontologies
- Historical and Environmental Studies
Clinique Romande de Réadaptation
2021-2024
École Polytechnique Fédérale de Lausanne
1995-2024
Pennsylvania State University
2017
Stroke patients vary considerably in terms of outcomes: some present 'natural' recovery proportional to their initial impairment (fitters), while others do not (non-fitters). Thus, a key challenge stroke rehabilitation is identify individual potential make personalized decisions for neuro-rehabilitation, obviating the 'one-size-fits-all' approach. This goal requires (i) prediction courses acute stage; and (ii) an understanding underlying neuronal network mechanisms. 'Natural' especially...
Background and Purpose: Structural brain networks possess a few hubs, which are not only highly connected to the rest of but also each other. These form rich-club, play central role in global organization. To investigate whether concept rich-club sheds new light on poststroke recovery, we applied novel network-theoretical quantification lesions patients with stroke compared outcomes what lesion size alone would indicate. Methods: Whole-brain structural 73 ischemic were reconstructed using...
Cortical excitation/inhibition dynamics have been suggested as a key mechanism occurring after stroke. Their supportive or maladaptive role in the course of recovery is still not completely understood. Here, we used transcranial magnetic stimulation (TMS)-electroencephalography coupling to study cortical reactivity and intracortical GABAergic inhibition, well their relationship residual motor function longitudinally patients with
We prove that the minimal $v_2$ self-map of 2-local spectrum $A_1$ is 32 periodic.
Recently we introduced a class $\widetilde{\mathcal{Z}}$ of $2$-local finite spectra and showed that all $Z\in \widetilde{\mathcal{Z}}$ admit $v_2$-self-map periodicity $1$. The aim this article is to compute the $K(2)$-local homotopy groups $\pi_*L_{K(2)}Z$ $Z \in using fixed point spectral sequence, give an almost complete computation. incompleteness lies in fact are unable eliminate one family $d_3$-differentials few potential hidden extensions, though conjecture these differentials...
Despite recent improvements, complete motor recovery occurs in <15% of stroke patients. To improve the therapeutic outcomes, there is a strong need to tailor treatments each individual patient. However, lack knowledge concerning precise neuronal mechanisms underlying degree and course its differences, especially view brain network properties despite fact that it became more clear disorder. The TiMeS project longitudinal exploratory study aiming at characterizing phenotypes large,...
At the prime $2$, Behrens, Hill, Hopkins and Mahowald showed $M_2(1,4)$ admits $32$-periodic $v_2$-self-map more recently authors joint with $A_1$ also $v_2$-self-map. This leads to question, whether there exists a finite $2$-local complex periodicity less than $32$. paper will answer question by producing class of spectra $\widetilde{\mathcal{Z}}$ all which admit $1$-periodic
NiGSP is a python-based toolbox aimed at facilitating the adoption of graph signal processing with an emphasis on multimodal brain imaging data. We present its standard workflow, that allows basic filtering operations and metrics computations, we introduce novel application to cerebral stroke consisting in creation subject-specific anatomical lesion-based filter be applied functional MRI timeseries.
Most studies on stroke have been designed to examine one deficit in isolation; yet, survivors often multiple deficits different domains. While the mechanisms underlying multiple-domain remain poorly understood, network-theoretical methods may open new avenues of understanding.Fifty subacute patients (7±3days poststroke) underwent diffusion-weighted magnetic resonance imaging and a battery clinical tests motor cognitive functions. We defined indices impairment strength, dexterity, attention....
Abstract Despite recent improvements, complete motor recovery occurs in less than 15% of stroke patients. To improve the therapeutic outcomes, there is a strong need to tailor treatments each individual patient. However, lack knowledge concerning precise neuronal mechanisms underlying degree and course its differences, especially view network properties despite fact that it became more clear disorder. The TiMeS project longitudinal exploratory study aiming at characterizing phenotypes large,...
Abstract Objective Cortical excitation/inhibition dynamics have been suggested as a key mechanism occurring after stroke. Their supportive or maladaptive role in the course of recovery is still not completely understood. Here, we used TMS-EEG coupling to study cortical reactivity and intracortical GABAergic inhibition, well their relationship residual motor function longitudinally large cohort stroke patients. Methods EEG responses evoked by TMS applied ipsilesional cortex were acquired 66...
Abstract Background Most studies on stroke have been designed to examine one deficit in isolation, yet survivors often multiple deficits different domains. While the mechanisms underlying multiple-domain remain poorly understood, network-theoretical methods may open new avenues of understanding. Methods 50 subacute patients (7±3days post-stroke) underwent diffusion-weighted magnetic resonance imaging and a battery clinical tests motor cognitive functions. We defined indices impairment...
Une paroi expérimentale renforcée par clouage a été réalisée dans le cadre d'un chantier autoroutier. Cet ouvrage, de 10 m hauteur, instrumenté manière à suivre l'évolution des déplacements et efforts mobilisés les clous au cours sa réalisation. Les résultats indiquent que sont concentrés une zone proche du parement efforts, nettement inférieurs la résistance barres, varient en fonction nature terrains traversés. Des calculs effectués éléments finis montrent l'on peut raisonnablement prédire...