A5022632302- Cancer-related molecular mechanisms research
- Cancer Diagnosis and Treatment
- Viral-associated cancers and disorders
- RNA modifications and cancer
- Obsessive-Compulsive Spectrum Disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neural and Behavioral Psychology Studies
- Functional Brain Connectivity Studies
- Genetic Mapping and Diversity in Plants and Animals
- Cancer, Lipids, and Metabolism
- Treatment of Major Depression
- Metabolomics and Mass Spectrometry Studies
- Tryptophan and brain disorders
- Diet and metabolism studies
- RNA Research and Splicing
- Chromatography in Natural Products
- Plant Stress Responses and Tolerance
- Infectious Encephalopathies and Encephalitis
- CRISPR and Genetic Engineering
- Protein Tyrosine Phosphatases
- PI3K/AKT/mTOR signaling in cancer
- Advanced Neuroimaging Techniques and Applications
- Genetics and Plant Breeding
- Crop Yield and Soil Fertility
Hunan Agricultural University
2022-2024
Qiqihar Medical University
2021-2024
Second Xiangya Hospital of Central South University
2023-2024
Central South University
2023-2024
Hebei General Hospital
2024
Yangzhou University
2023
Anqing Normal University
2023
First Affiliated Hospital of Nanchang University
2022
Nanchang University
2022
Resistance to endocrine therapy represents a major concern for patients with estrogen receptor α-positive (ERα+) breast cancer. Endocrine resistance is commonly mediated by activated E2F signaling. A better understanding of the mechanisms governing E2F1 activity in resistant cells could reveal strategies overcoming resistance. Here, we identified long noncoding RNA (lncRNA) actin gamma 1 pseudogene 25 (AGPG) as regulator endocrine-resistant Expression AGPG was increased cancer cells, which...
Abstract Background Previous studies discovered the presence of abnormal structures and functions in brain regions patients with obsessive-compulsive disorder (OCD). Nevertheless, whether structural changes are coupled alterations dynamic functional connectivity (dFC) at rest medicine-free OCD remains vague. Methods Three-dimensional T 1 -weighed magnetic resonance imaging (MRI) resting-state MRI were performed on 50 healthy controls (HCs). Firstly, differences gray matter volume (GMV)...
Maize has become one of the most widely grown grains in world, and stay-green mutant allows these plants to maintain their green leaves photosynthetic potential for longer following anthesis than non-mutated plants. As a result, have higher production rate non-stay-green varieties due prolonged grain-filling period. In this study, candidate genes related visual at maturation stage maize were investigated. The F2 population was derived from T01 (stay-green) Xin3 (non-stay-green) cross. Two...
Anomalies in regional homogeneity (ReHo) have been documented patients with major depressive disorder (MDD) and sleep disturbances (SDs). This investigation aimed to scrutinize changes ReHo MDD comorbid SD, devise potential diagnostic biomarkers for detecting sleep-related conditions MDD.Patients healthy controls underwent resting-state functional magnetic resonance imaging scans. SD severity was quantified using the 17-item Hamilton Rating Scale Depression. Subsequent acquisition of data,...
Disrupted functional asymmetry of cerebral hemispheres may be altered in patients with obsessive-compulsive disorder (OCD). However, little is known about whether anomalous brain asymmetries originate from inter- and/or intra-hemispheric connectivity (FC) at rest OCD. In this study, resting-state magnetic resonance imaging was applied to 40 medication-free OCD and 38 gender-, age-, education-matched healthy controls (HCs). Data were analyzed using the parameter (PAS) support vector machine...
We demonstrate that endonuclease deficient Clustered Regularly Interspaced Short Palindromic Repeats CRISPR-associated Cas9 protein (dCas9) fused to the photo-convertible fluorescence monomeric mEos3.1 (dCas9-mEos3) can be used resolve sub-diffraction limited features of repetitive gene elements, thus providing a new route investigate high-order chromatin organization at these sites.
The mechanism of synergetic effects multi-components on multi-targets in traditional Chinese medicine (TCM) is one the bottlenecks for TCM modernization and internationalization. Network biology approach was developed recent years provided an important novel idea to study pharmacological TCM. This review introduced mathematical basis network biology, as well feasibility research using expected be further used analyzing TCM, guiding drug development inheriting carrying forward fundamental principle
Soil contamination by heavy metals has become a prevalent topic due to their widespread release from industry, agriculture, and other human activities. Great progress been made in elucidating the uptake translocation of cadmium (Cd) accumulation rice. However, there is still little known about corresponding maize. In current study, we performed comparative RNA-Seq-based approach identify differentially expressed genes (DEGs) maize immature kernel related Cd stress. total, 55, 92, 22, 542...
Depressive symptoms are the most prevalent comorbidity in individuals with obsessive-compulsive disorder (OCD). The objective of this study was to investigate dynamic characteristics resting-state neural activities OCD patients depressive symptoms.
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