A5102027308- Cell Adhesion Molecules Research
- Anesthesia and Neurotoxicity Research
- bioluminescence and chemiluminescence research
- Cellular Mechanics and Interactions
- Photochromic and Fluorescence Chemistry
- Glioma Diagnosis and Treatment
- Anesthesia and Sedative Agents
- Intensive Care Unit Cognitive Disorders
Samsung Medical Center
2023
Sungkyunkwan University
2023
Konkuk University
2015
Triclosan is an antimicrobial or sanitizing agent used in personal care and household products such as toothpaste, soaps, mouthwashes kitchen utensils.There are increasing evidence of the potentially harmful effects triclosan many systemic cellular processes body.In this study, we investigated survivability cultured rat neural stem cells (NSCs).Cortical from embryonic day 14 embryos were isolated vitro.After stabilizing culture, was introduced to with concentrations ranging 1 μM 50 varied...
Glioblastoma (GBM) is a representative malignant brain tumor characterized by dismal prognosis, with survival rates of less than 2 years and high recurrence rates. Despite surgical resection several alternative treatments, GBM remains refractory disease due to its aggressive invasiveness resistance anticancer therapy. In this report, we explore the role fibronectin type III domain containing 3B (FNDC3B) potential as prognostic therapeutic biomarker in GBM. exhibited significantly higher...
Objective : Isoflurane, a widely used common inhalational anesthetic agent, can induce brain toxicity. The challenge lies in protecting neurologically compromised patients from neurotoxic anesthetics. Choline alfoscerate (L-α-Glycerophosphorylcholine, α-GPC) is recognized for its neuroprotective properties against oxidative stress and inflammation, but optimal therapeutic window indications are still under investigation. This study explores the impact of α-GPC on human astrocytes, most...
Abstract Malignant brain tumor (MBT) is an aggressive with high drug-resistance and recurrence rates. Using ‘Oncopression’ big data analysis, we found that a fibronectin-related protein, fibronectin type III domain containing 3B (FNDC3B), was specifically overexpressed in patients conducted pilot mechanism study on the role of FNDC3B MBT. We evaluated functional significance MBT using specific siRNA performing cell viability assay, real-time qPCR, Western blot, 3D-invasion wound healing...