A5101892506- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- Neurosurgical Procedures and Complications
- Glioma Diagnosis and Treatment
- Spinal Fractures and Fixation Techniques
- Intracerebral and Subarachnoid Hemorrhage Research
- Spine and Intervertebral Disc Pathology
- Meningioma and schwannoma management
- Cerebrovascular and Carotid Artery Diseases
- Head and Neck Surgical Oncology
- Traumatic Brain Injury Research
- Spinal Hematomas and Complications
- Cell Adhesion Molecules Research
- Teratomas and Epidermoid Cysts
- Pituitary Gland Disorders and Treatments
- Vascular Malformations Diagnosis and Treatment
- Cerebrospinal fluid and hydrocephalus
- Sinusitis and nasal conditions
- Advanced biosensing and bioanalysis techniques
- Acute Ischemic Stroke Management
- Case Reports on Hematomas
- Vascular Procedures and Complications
- Epilepsy research and treatment
- Moyamoya disease diagnosis and treatment
- Neuroscience and Neuropharmacology Research
Korea University Medical Center
2016-2025
Korea University
2000-2021
CHA University
2019
Seoul National University
2017-2018
Virginia Commonwealth University
2005
Okmeydanı Eğitim ve Araştırma Hastanesi
2001
It is well known that the cognitive functions of juveniles recover to a greater extent than adult patients following traumatic brain injury (TBI). The exact mechanisms underlying this age-related disparity are unknown; however, we speculate improved recovery in TBI may be associated with an endogenous neurogenic response hippocampus. We, therefore, examined effects on cellular proliferation and differentiation dentate gyrus (DG) hippocampus juvenile rats lateral fluid percussion (FPI)....
BACKGROUND Cerebral angiography, although invasive, remains the most accurate diagnostic tool for neurovascular diseases. While transfemoral cerebral angiography (TFCA) is conventional approach, transradial (TRCA) has gained interest due to potential benefits, such as reduced hematoma risk and shorter recovery times. However, procedure times influencing factors remain debated. This retrospective study from a single center aimed compare time in 100 patients undergoing TFCA 93 TRCA. MATERIAL...
Extra-domain B of fibronectin (EDB-FN) is an alternatively spliced form with high expression in the extracellular matrix neovascularized tissues and malignant cancer cells.In this study, we evaluated practicality using EDB-FN as a biomarker therapeutic target for gliomas (MGs), representative intractable diseases involving brain tumors.Methods: The microarray-and sequence-based patient transcriptomic database 'Oncopression' tissue microarray MG samples were analyzed.EDB-FN data extracted...
Our purpose of this study was to assess the cerebral hemodynamic improvement with perfusion computed tomography (CT), before and after superficial temporal artery (STA) middle (MCA) bypass surgery in patients cerebrovascular steno-occlusive diseases including both moyamoya disease nonmoyamoya steno-occlusions.Twenty-four STA-MCA bypasses were performed 22 symptomatic diseases, diseases. Brain CT images obtained surgery. The relative parameters such as blood volume (CBV), flow (CBF), mean...
A 69-year-old male presented with a rare spinal angiolipoma manifesting as history of back pain, and numbness in both lower limbs, which progressed over period 5 years. Total T10-T12 laminectomy was performed the tumor removed en bloc. The symptoms gradually improved postoperatively. Spinal is an uncommon benign extradural spine, accounts for 0.14-1.2% all tumors cause cord compression. Recognition this entity crucial curable paraplegia pain.
The purpose of this study was to evaluate the effectiveness middle meningeal artery embolization (MMAE) in elderly high-risk patients with symptomatic chronic subdural hematoma (CSDH) terms reduction volume and recurrence rate.We retrospectively reviewed data prospectively collected from nine who underwent 13 MMAE for CSDH between June 2017 May 2022. measured using a computer-aided volumetric analysis program. Hematoma changes during follow-up period were analyzed clinical outcomes...
Abstract OBJECTIVE A clinical and radiological follow-up study was undertaken to assess the safety, efficacy, complication rate associated with instrumented facet fusion of lumbar lumbosacral spine. METHODS This involved 99 patients degenerative disorders who were treated surgically at authors' neurosurgical department followed for more than 2 years. Eighty-two underwent one-level treatment Grade I or II spondylolisthesis accompanying spinal canal stenosis (44 patients) recurrent disc...
Object. This study was conducted to determine whether perfluorocarbons (PFCs) improve brain oxygenation and reduce ischemic damage in an acute subdural hematoma (SDH) model rats. Methods. Forty adult male Sprague—Dawley rats were allocated four groups: 1) controls, SDH treated with saline 30% O 2 ; 2) 30-PFC group, PFC infusion 3) 100-O 100% 4) 100-PFC plus . Ten minutes after the induction of SDH, a single dose infused or administered simultaneously. Four hours later, half killed by...
Background Subdural hygromas are often found bilaterally in spontaneous intracranial hypotension (SIH). They frequently progress to chronic subdural hematomas (CSDHs), and if the formed, it is difficult consider SIH as an underlying cause. Whether or not among patients presenting bilateral fluid collections (hygromas CSDHs) clinically important because treatment strategy should be different between them. Objectives We designed a retrospective case‐control study figure out differential...
Glioblastoma (GBM) is a representative malignant brain tumor characterized by dismal prognosis, with survival rates of less than 2 years and high recurrence rates. Despite surgical resection several alternative treatments, GBM remains refractory disease due to its aggressive invasiveness resistance anticancer therapy. In this report, we explore the role fibronectin type III domain containing 3B (FNDC3B) potential as prognostic therapeutic biomarker in GBM. exhibited significantly higher...
<b><i>Background:</i></b> Clinical outcome in patients with acute ischemic stroke (AIS) caused by large vessel occlusion (LVO) is not satisfactory if reperfusion treatment fails or tried. <b><i>Aims:</i></b> We aimed to assess the efficacy and safety of urgent superficial temporal-to-middle cerebral artery (STA-MCA) bypass surgery selected patients. <b><i>Methods:</i></b> Patients who were diagnosed LVO-induced AIS...
Aneurysms of the distal anterior cerebral artery (DACA) are rare and their surgical treatments present some unique difficulties from a technical standpoint. In this report, we presented our experiences cases with DACA aneurysms, analyzed clinical features prognostic factors affecting final outcomes. Among 770 intracranial aneurysms operated 1990 to 1998, 19 (2.5%) were studied retrospectively. The characteristic findings female preponderance (M:F = 1:2.8), common multiple (57.9%), frequent...
Abstract BACKGROUND Many physicians consider aneurysmal wall enhancement (AWE) on high resolution-vessel imaging (HR-VWI) as an biomarker of unstable unruptured intracranial aneurysms (UIAs). OBJECTIVE To evaluate the clinical value different AWE signal intensities (SIs) by assessing correlation between SIs and surgical findings rupture risk assessment tools. METHODS Twenty-six patients with 34 who underwent clipping were included. The corrected SI was calculated comparing T1-weighted images...
Glioblastoma multiforme (GBM) is the most common glial tumor of adult brain. However, primary GBM medulla oblongata a rarity. To best our knowledge, only four cases have been reported so far in literature, and this second report conventional adults. We describe case 51-year-old female, who presented with heterogeneous mass exophytic feature located caudal brain stem that was approached near total removal achieved by median suboccipital route. A literature review emphasis on anatomical...
ABSTRACT This study was designed to investigate (i) extracellular matrix specify adhesive substrates human dura mater cell (hDMC); (ii) the alteration on adhesion‐related molecules in hDMC; and (iii) secreted metalloproteinases (MMPs) linked with remodeling after exposure inflammation. The hDMC cultured from tissue, studies were performed co‐culturing macrophage like THP‐1 cells (Mϕ). adhesion of co‐cultured through collagen I increased 6.4‐fold IV 5.0‐fold compared naïve ( p < 0.001)....