A5058808478- Pulsed Power Technology Applications
- Particle Accelerators and Free-Electron Lasers
- Gyrotron and Vacuum Electronics Research
- Particle accelerators and beam dynamics
- Integrated Circuits and Semiconductor Failure Analysis
- Electrostatic Discharge in Electronics
- Laser-Plasma Interactions and Diagnostics
- Advanced X-ray and CT Imaging
- Particle Detector Development and Performance
- Immunotherapy and Immune Responses
- Ultra-Wideband Communications Technology
- T-cell and B-cell Immunology
- Magnetic confinement fusion research
- CAR-T cell therapy research
- Thermal Analysis in Power Transmission
- Advanced X-ray Imaging Techniques
- Radiation Detection and Scintillator Technologies
- Medical Imaging Techniques and Applications
- Laser Design and Applications
- Quantum Mechanics and Applications
- Plasma Diagnostics and Applications
- Electromagnetic Launch and Propulsion Technology
- Advanced Biosensing Techniques and Applications
- Nuclear Physics and Applications
- Lightning and Electromagnetic Phenomena
Centre d'Études Scientifiques et Techniques d'Aquitaine
1993-2012
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
1993-2012
Polygon Physics (France)
2003-2006
CEA DAM Île-de-France
2003
Boston College
1999
Routine clinical assays, such as conventional immunohistochemistry, often fail to resolve the regional heterogeneity of complex inflammatory skin conditions. We introduce MANTIS (Multiplex Annotated Tissue Imaging System), a flexible analytic pipeline compatible with routine practice, specifically designed for spatially resolved immune phenotyping in experimental or samples. On basis phenotype attribution matrices coupled α-shape algorithms, projects representative digital landscape while...
This paper presents the design and experimental results of a hand-portable, self-contained, repetitive radiation source high-power ultrawideband (UWB) pulses. consists deployed UWB antenna driven by high-pulsed power (HPP) generator powered self-contained 50-kV rapid charger at repetition rates up to 100 Hz. By changing HPP generator, two different electric wave shapes with frequency spectra can be generated. Each is based on use Marx generator. On one hand, 200-kV/1.4-J associated coaxial...
This work presents the highlights of high-voltage, positive-polarity experiments on ASTERIX generator characterizing rod-pinch diode at up to 6 MV as a source for high-resolution, flash radiography. The paper reviews experimental results and analyses including conversion positive polarity, electrical radiation characteristics, comparisons numerical simulation, composite performance. A minimum LANL diameter 1.32 mm with dose 23.7 rad(air) 1 m was achieved peak voltage 5.9 MV, leading...
The angular distribution of radiation from a rod-pinch diode is examined with coupled PIC-Monte-Carlo simulations using the LSP code (D.R. Welch, et al., 2001) and compared dose measurements on ASTERIX pulsed-power generator. For 4- to 6-MV voltage range accessible in experiments, both measured simulated doses at 1 m were 25 38 rad-LiF forward direction (0/spl deg/). calculated 90/spl deg/ 1.2-1.8 times larger than forward-directed depending rod diameter. This also agreement variation (F.C....
This paper presents the design, fabrication, and characterization of a compact wideband antenna for high-power microwave applications. The antennas proposed are array patches with high compactness less than λ/10 thick. concept developed can be fed by high-voltage signals (up to 60 kV) in repetitive operation. Two designs produced at central frequencies 350 MHz 1 GHz. Their relative bandwidth is larger 40% 25% GHz S11 <; - 10 dB, respectively. arrays studied produce gain more 14 dB.
Abstract Routine clinical assays, such as conventional immunohistochemistry, often fail to resolve the regional heterogeneity of complex inflammatory skin conditions. Here we introduce MANTIS (Multiplexed Annotated Tissue Imaging System), a flexible analytic pipeline compatible with routine practice, specifically-designed for spatially-resolved immune phenotyping in experimental or samples. Based on phenotype attribution matrices coupled α-shape algorithms, projects representative digital...
The high performance required for the French Radiographic Hydrotest Facility is tightly connected to quality of electron beam. As part AIRIX program an Integrated Test Stand named PIVAIR achieved at CESTA. Many tools have been developed control and optimize beam parameters. At first, we describe alignment technique chosen PIVAIR. Since essentially time dependent characteristics, all diagnostics are resolved. Emittance measurement which uses pepper-pot associated a fast scintillator radiator...
AIRIX Flash X-ray Radiographic facility is based on a 4 MeV-3,5 kA pulsed electron injector and 16 MeV induction accelerator. The accelerator will consist of 64 cells powered by 32 H.V. generators operated at 250 kV. final 20 beam be focused target designed for conversion. At CESTA, PIVAIR testbed as validation step up to 8 MeV. has been connected with accelerating cells, increasing energy 7.2 Two kinds have developed tested. A focusing experiment planned spot diameter measurements. After...
AT PEM (Polygone d'Experimentation de Moronvilliers), the CEA will build a flash x-ray generator based on LTD technology. In this machine, electrical energy is transmitted to X-ray diode by MITL (magnetically insulated transmission line). To study behavior of kind high voltage line and fed diode, has undertaken install new coaxial Marx ASTERIX, located at CEG (Centre d'Etudes Gramat). This modification associate present vacuum line, element that increase radius internal conductor decrease...
This paper presents a high voltage pulse source which is able to generate ultra wideband (UWB) pulses during about 1 ns through 16 antennas array.This UWB composed of 50 kV DC supply, Tesla transformer amplify this up 400 kV, gaseous pressurized peaking switch and an impedance (50 Ω → 3.125 Ω).This output value corresponds the input sixteen array.That why distributor needed in order feed antenna array.In paper, capacitive line divider used characterise generated are particularly...
The rod-pinch diode is evaluated as a pulsed radiographic source for voltages up to 6 MV on the ASTERIX generator. Peak currents of 105 135 kA are delivered peak 5.2 6.3 MV. couples efficiently generator 1.6-, 2.0-, and 3.0-mm diameter tungsten (or gold) anode rods producing 40-ns radiation pulse. coupling degraded if anode-cathode gap (Rc - RA) too small (7.5 mm), rod extension short (10 or aspect ratio Rc/RA large (20). For standard anodes considered here, figure-of-merit (FOM) largest [11...
AIRIX is a linear induction accelerator that will be used for flash X-ray radiography. It deliver 20 MeV, 3.5 kA, 60 ns electron beam. This now under installation at PEM. The injector, produces 4 beam and 16 cells powered by 8 high voltage generators (250 kV per cell) are already operational. At this point, the LIA has same dimension than PIVAIR prototype installed CESTA. paper relates characterization we have made to compare two accelerators. Those experiments consist first, on imaging...
Abstract Background The field of drug development is witnessing a remarkable surge in the innovative strategies. There need to develop technological platforms capable generating human data prior progressing clinical trials. Methods Here we introduce new flexible solution designed for comprehensive monitoring natural skin ecosystem's response immunogenic drugs over time. Based on unique bioengineering preserve surgical resections long survival state, it allows first time analysis resident...
AIRIX Induction Accelerator (16-20 Mev, 3.5 kA, 60 ns) has been designed at CESTA for flash X-ray application. After two years of experimental studies on prototype cells and High Voltage Generators we started in 1994 the PIVAIR milestone which is a validation step 8 MeV AIRIX. The injector assembled tested; it produces kA electron beam 4 with good voltage flatness (/spl plusmn/0.35%) low emittance. An accelerating module eight induction constructed four have first connected injector. other...
AIRIX is a 2 kA, 20 MeV, 60 ns linear accelerator dedicated to X-ray flash radiography. During regular running phase, the primary electron beam accelerated and focused on high atomic number target in order generate X-rays by bremβtrahlung mainly. The huge energy density deposited into material such that temperature rises up 15000° K clusters particles are violently ejected from surface. In mechanism, backward emission speed can reach 5 km s <sup xmlns:mml="http://www.w3.org/1998/Math/MathML"...
AIRIX flash X-ray Radiographic facility is based on a 4 MeV- 3,5 kA pulsed electron injector and 16 MeV induction accelerator. The accelerator will consist of 64 cells powered by 32 H.V. Pulsed generators operated at 250 kV. final 20 beam be focused target designed for conversion. At CESTA, PIVAIR testbed as validation step up to 8 MeV. has been connected with accelerating cells, increasing energy 7.2 Two kinds have developed tested. A focusing experiment performed spot diameter...
The AIRIX accelerator is running with a 1.92 kA (single pulse 60 ns) electron beam for two years. optimisation of the transport has to minimise transverse BBU oscillations and preserve quality 20 MeV at end accelerator. This minimisation needs very precise alignment. Secondly, use higher axial magnetic field also minimises oscillations. In this way, we have installed new power supplies generate required fields. We show results that obtained when another solenoid was positioned between...
A new electron accelerator is now being studied and designed for flash radiography application. It consists of a pulsed injector (4 MeV-3,5 kA-60 ns) an induction increasing the energy electrons up to 20 MeV. We briefly describe Injector built by PSI similar DARHT at LANL. present studies experimental tests carried out in order design build cells high voltage generators suitable this Information given on PIVAIR milestone planned beforehand validation whole AIRIX machine. Cavity separated...