A5038617767- Orthopedic Surgery and Rehabilitation
- Foot and Ankle Surgery
- Tendon Structure and Treatment
- Bone Metabolism and Diseases
- Osteoarthritis Treatment and Mechanisms
- Musculoskeletal synovial abnormalities and treatments
- Bone and Joint Diseases
- Shoulder Injury and Treatment
- Inflammatory mediators and NSAID effects
- Bone health and treatments
- Rheumatoid Arthritis Research and Therapies
- Bee Products Chemical Analysis
- Nanoplatforms for cancer theranostics
- Traditional Chinese Medicine Studies
- Diabetic Foot Ulcer Assessment and Management
- Immune cells in cancer
- Biological Activity of Diterpenoids and Biflavonoids
- Phytochemistry and Biological Activities
- Parkinson's Disease and Spinal Disorders
- Health Literacy and Information Accessibility
- Nanoparticle-Based Drug Delivery
- Shoulder and Clavicle Injuries
Jinan University
2024
First Affiliated Hospital of Jinan University
2019-2024
Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
2020-2022
Jinan University
2020
This study aims to explore the correlation between alterations in blood glucose levels and osseointegration as well biomechanical properties of nHA/PLLA absorbable screws, elucidate impact DM on bone metabolism surrounding screws. 75 rats were randomly assigned either Diabetes mellitus (DM) group control group. was induced through intraperitoneal injection 1% streptozotocin. A single screw surgically implanted into medial tibia each rat both groups. Rats euthanized at 4 weeks, 8 weeks 12...
Abstract Background To compare the clinical efficacies of arthroscopic anterior talofibular ligament suture augmentation repair and modified in patients with chronic ankle instability (CAI). Methods From October 2019 to August 2020, 100 CAI were enrolled after propensity score matching analysis observed for two years. Among them, 50 underwent other repair. The treatments evaluated using American Orthopedic Foot Ankle Society (AOFAS) rating scale, visual analog scale (VAS), drawer test...
The purpose of this study was to develop an optimal diabetes-osteoarthritis (DM-OA) mouse model validate that diabetes aggravates osteoarthritis (OA) and evaluate the microarchitecture, chemical composition, biomechanical properties subchondral bone (SB) as a consequence DM-OA-induced damage induced.Mice were randomly divided into three groups: DM-OA group, OA sham group. Blood glucose levels, body weight, food intake all animals recorded. Serum calcium (Ca) osteocalcin (OCN) levels compared...
Objective: To explore the biomechanical efficacy of arthroscopic all-inside anterior talofibular ligament (ATFL) suture augmentation repair, plus repair and tibiofibular ligament-distal fascicle (ATiFL-DF) transfer so as to provide a basis for accurate selection ATFL in clinical practice. Methods: Twenty-four (12 pairs) fresh frozen human cadaver ankle specimens were used. Six set normal group, other 18 used establish injury models. The was then repaired using (suture group), (plus group)...
In osteoarthritis (OA), articular cartilage is continuously submerged in a hypoxic environment throughout life, and hypoxia-inducible factors (HIFs) play crucial role OA progression. Among the various HIF phenotypes, HIF-1α positively contributes to maintaining stability of matrix. contrast, HIF-2α has detrimental effect, leading chondrocyte apoptosis exacerbating inflammation. Notably, there currently no simultaneous regulation for treatment. Thus, biomimetic gene vector (MENP) was...
A coracoid process fracture combined with an acromioclavicular (AC) joint dislocation is uncommon injury that typically causes significant pain and limits shoulder movement. Open reduction internal fixation have been the traditional treatment approach. However, arthroscopic techniques are emerging as a promising alternative for managing these injuries. 35-year-old woman presented right following accidental fall. Imaging studies revealed along AC dislocation. The was classified Eyres Type...
Abstract Background : The purpose of this study is to develop an optimal DM-OA mice model; validate that diabetes aggravates OA; and evaluate the microarchitecture, chemical composition biomechanical properties SB as a consequence damaged induced by OA. Methods: Mice were randomly divided into three groups: group, OA group Sham group. Blood glucose levels, body weight food intake all animals recorded. A semi-quantitative grading system (OARSI) was used evaluated cartilage degeneration....
Tendon impairment is a common injury associated with of range motion and pain. Currently, evidence has confirmed that natural herbs contribute to orthopedics have shown excellent results in the clinical management tendon impairment. Shujin Huoxue tablet (SHT) its complex prescriptions are regularly used rupture therapy positive results. This study aimed discover potential molecules promote healing. The Chinese traditional medicine system pharmacological database analysis platform (TCMSP)...
We conducted a field investigation of 803 residents in Guangzhou through self-designed questionnaire to analyze the ways which different ages obtained medical information and differences trust information. The survey results show that have access their respective levels are also different. This is reason why relevant units departments should publish targeted according each age group, order enable obtain more efficiently. this study new media had large proportion current information, so has...
Objective To systematically assess the relationship between metabolic syndrome and osteoarthritis. Methods Databases including PubMed, Excerpta Medica Database(EMbase), China Biology Medicine disc (CBM), Science Technology Journal Database(VIP), Cochrane Library(Issue 5, 2018), National Knowledge Infrastructure (CNKI) WanFang Data were searched for published studies investigation of correlation osteoarthritis from inception to May 2018. The observational trials about included, repeat...
Abstract Background: This study intends in evaluating the comparsion between arthroscopic arthrodesis and open surgery for patients with ankle arthritis by performing a meta-analysis. Methods: A literature search this meta-analysis was conducted using four English databases (Pubmed, Embase, Medline Cochrane Library), up to August 2019. These included two prospective cohort 7 retrospective studies, enrolling total of 507 arthritis. Result: For fusion rate, pooled data showed significantly...
Abstract The authors have withdrawn this preprint from Research Square
Abstract New strategies enhancing both targetability of chemotherapy drugs and synergistic effects immunotherapy remain a major challenge for the solid tumor therapy. In this research, novel biomimetic nanoparticle system possessed function targeting immune synergy was designed to accomplish above requirements. The membranes coated on mesoporous silica nanoparticles loaded with named doxorubicin (DOX); it modified by glycosyl-phosphatidylinositol (GPI) anchored anti-HER2 single chain...