Gaozhan Zhao

ORCID: 0009-0008-8506-376X
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About
Contact & Profiles
Research Areas
  • Plant Molecular Biology Research
  • Aluminum Alloys Composites Properties
  • RNA modifications and cancer
  • Signaling Pathways in Disease
  • Light effects on plants
  • Photosynthetic Processes and Mechanisms
  • Plant nutrient uptake and metabolism

Tsinghua University
2018-2023

Center for Life Sciences
2018-2023

MicroRNAs (miRNAs) play an important role in gene regulation. In Arabidopsis , mature miRNAs are processed from primary miRNA transcripts by the Dicing complex that contains Dicer-like 1 (DCL1), SERRATE (SE), and Hyponastic Leaves (HYL1). The can form nuclear dicing bodies (D-bodies) through SE phase separation. Here, we report Cyclophilin71 (CYP71), a peptidyl-prolyl isomerase (PPIase), positively regulates processing. We show CYP71 directly interacts with enhances its separation, thereby...

10.1073/pnas.2305244120 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2023-08-28

RNA polymerases IV and V (Pol Pol V) are required for the generation of noncoding RNAs in RNA-directed DNA methylation (RdDM). Their subunit compositions resemble that II. The mechanism accessory factors involved their assembly remain largely unknown. In this study, we identified mutant alleles MINIYO (IYO), QUATRE-QUART2 (QQT2), NUCLEAR POLYMERASE B11/D11/E11 (NRPB/D/E11) cause defects RdDM Arabidopsis thaliana. We found IV-dependent small interfering V-dependent transcripts were greatly...

10.1105/tpc.17.00380 article EN The Plant Cell 2018-01-18
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