- Plant Molecular Biology Research
- Aluminum Alloys Composites Properties
- RNA modifications and cancer
- Signaling Pathways in Disease
- Light effects on plants
- Photosynthetic Processes and Mechanisms
- Plant nutrient uptake and metabolism
Tsinghua University
2018-2023
Center for Life Sciences
2018-2023
MicroRNAs (miRNAs) play an important role in gene regulation. In Arabidopsis , mature miRNAs are processed from primary miRNA transcripts by the Dicing complex that contains Dicer-like 1 (DCL1), SERRATE (SE), and Hyponastic Leaves (HYL1). The can form nuclear dicing bodies (D-bodies) through SE phase separation. Here, we report Cyclophilin71 (CYP71), a peptidyl-prolyl isomerase (PPIase), positively regulates processing. We show CYP71 directly interacts with enhances its separation, thereby...
RNA polymerases IV and V (Pol Pol V) are required for the generation of noncoding RNAs in RNA-directed DNA methylation (RdDM). Their subunit compositions resemble that II. The mechanism accessory factors involved their assembly remain largely unknown. In this study, we identified mutant alleles MINIYO (IYO), QUATRE-QUART2 (QQT2), NUCLEAR POLYMERASE B11/D11/E11 (NRPB/D/E11) cause defects RdDM Arabidopsis thaliana. We found IV-dependent small interfering V-dependent transcripts were greatly...