A5038557780- Ovarian cancer diagnosis and treatment
- Mycobacterium research and diagnosis
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiovascular Disease and Adiposity
- Endometriosis Research and Treatment
- Hedgehog Signaling Pathway Studies
- Uterine Myomas and Treatments
- Cervical Cancer and HPV Research
- Reproductive Health and Technologies
- Pregnancy and preeclampsia studies
- Cytokine Signaling Pathways and Interactions
- Reproductive Biology and Fertility
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- COVID-19 Impact on Reproduction
- Ovarian function and disorders
- COVID-19 and healthcare impacts
Shandong Maternal and Child Health Hospital
2020-2024
Jinan Military General Hospital
2014-2017
Polycystic ovary syndrome (PCOS) is a gynaecological endocrine disease. The objective of the present study was to investigate role GTPase immunity-associated protein (GIMAP) 7 in PCOS. A PCOS rat model established using dehydroepiandrosterone injection. data showed that GIMAP7 mainly located granulosa cells and abundantly expressed ovarian rats. silencing decreased blood glucose levels, HOMA-IR scores, number cystic follicles. In addition, corrected erratic oestrous cycles, inhibited...
Inflammation is involved in the pathogenesis of preeclampsia. Omentin a newly discovered adipokine that possesses an anti-inflammatory function. The aim this study was to determine association serum omentin-1 concentration with presence and severity preeclampsia.Serum concentrations were measured 128 women preeclampsia 96 uncomplicated pregnancies using enzyme-linked immunosorbent assay method.Patients had significantly lower compared healthy controls. In addition, those patients severe mild...
Uterine leiomyomas are common clinical gynecological tumors, which a major health concern for many women. In the current study, we aimed to investigate effect of paclitaxel (PTX) on uterine leiomyomas. A mouse model was established by estradiol benzoate, followed treatment with increasing doses PTX. PTX showed no dose-limiting toxicity that affected survival mice, and able restore apoptosis level uterus tissues mice normal levels. this discovered played critical role in promoting leiomyomas,...
Objective . To study the reproductive hormones, semen quality, psychology, and sexual function of childbearing age men after recovery from Corona Virus Disease‐2019 (COVID‐19) infection. Materials Methods We recruited 387 who recovered COVID‐19 infection underwent prepregnancy health checks at Reproductive Center Shandong Maternal Child Health Hospital January to March 2023 as subjects. Routine analysis hormones were performed. The clinical symptoms, anxiety, depression, erectile function,...