A5067636562- COVID-19 epidemiological studies
- Respiratory viral infections research
- COVID-19 and Mental Health
- Inflammatory mediators and NSAID effects
- Cancer, Lipids, and Metabolism
- Pediatric health and respiratory diseases
- Endoplasmic Reticulum Stress and Disease
- Misinformation and Its Impacts
- Estrogen and related hormone effects
- Animal Disease Management and Epidemiology
- Vaccine Coverage and Hesitancy
- Liver physiology and pathology
- Influenza Virus Research Studies
- Liver Disease Diagnosis and Treatment
- Tracheal and airway disorders
National Centre for Infectious Diseases
2020
National University Health System
2018
National University of Singapore
2018
Temasek Polytechnic
2012
To evaluate how public perceptions and trust in government communications affected the adoption of protective behaviour Singapore during coronavirus disease 2019 (COVID-19) pandemic.We launched our community-based cohort to assess infectious outbreaks mid-2019. After first case COVID-19 was reported on 23 January, we a series seven surveys both existing regularly enrolled new participants every 2 weeks. As well as sociodemographic properties participants, recorded changing responses judge...
Metabolic dysfunction-associated steatotic liver disease (MASLD) is generally asymptomatic in the early stages but, without appropriate intervention, it can progress to severe morbidities. To elucidate molecular mechanisms of development MASLD, we performed transcriptomic analysis on biopsies and metabolomic plasma samples from 109 obese individuals with no pathology or MASLD. The metabolome remodeled by parenchymal accumulation neutral lipids, whereas displayed little differences....
A(H1N1) strains of Influenzavirus were responsible for 2 pandemics in the last 100 years. Because infections experienced early life may have a long-lasting influence on future immune response against other influenza strains, we drew previously collected seroincidence data from Singapore (n = 2,554; June-October 2009) to investigate whether 1918 pandemic virus and its descendants produced an age-related signature responses A/California/7/2009(H1N1)pdm09 2009. Hemagglutination inhibition...
Background: To demonstrate the use of a cohort for assessing knowledge, perceptions and behaviours Singapore population towards infectious disease outbre
Abstract PTGS-2 is an rate-limiting enzyme that can be induced by several factors including mitogens, cytokines, growth and tumor promoters. It catalyzes the formation of Prostaglandin E2 (PGE2) favors carcinogenic processes. Overexpression gene encoding was observed in human malignancies colorectal cancer. Various functional genetic polymorphisms present were shown to influence expression level protein affect individuals’ susceptibility developing Whole screening healthy local Chinese...