A5027806092- Climate Change and Health Impacts
- Air Quality and Health Impacts
- Dental materials and restorations
- Bone Tissue Engineering Materials
- Energy and Environment Impacts
- Dental Implant Techniques and Outcomes
- Global Health Care Issues
- RNA modifications and cancer
- Cancer Genomics and Diagnostics
- Neuroblastoma Research and Treatments
- Anaerobic Digestion and Biogas Production
- Pickering emulsions and particle stabilization
- Genomics and Rare Diseases
- Wastewater Treatment and Nitrogen Removal
- Sarcoma Diagnosis and Treatment
- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Microbial bioremediation and biosurfactants
- Microbial Community Ecology and Physiology
- Additive Manufacturing and 3D Printing Technologies
- Rock Mechanics and Modeling
- Heat and Mass Transfer in Porous Media
- Membrane Separation Technologies
- Dental Research and COVID-19
- Landslides and related hazards
Sun Yat-sen University
2024-2025
Stomatology Hospital
2024-2025
Peking University
2021-2024
Chongqing University
2021-2024
National Health and Family Planning Commission
2022-2024
Tokyo Medical and Dental University
2020-2024
University of California, San Francisco
2018-2024
University of Cincinnati
2023
China University of Mining and Technology
2022
Shandong University of Science and Technology
2021
Osteosarcoma is a highly aggressive cancer for which treatment has remained essentially unchanged more than 30 years. characterized by widespread and recurrent somatic copy-number alterations (SCNA) structural rearrangements. In contrast, few point mutations in protein-coding genes have been identified, suggesting that within SCNAs are key oncogenic drivers this disease. rearrangements heterogeneous across osteosarcoma cases, the need genome-informed approach to targeted therapy. To identify...
We aimed to assess the crystallography, microstructure and flexural strength of zirconia-based ceramics made by stereolithography (SLA). Two additively manufactured 3 mol% yttria-stabilized tetragonal zirconia polycrystals (3Y-TZP: LithaCon 3Y 230, Lithoz; 3D Mix zirconia, 3DCeram Sinto) one alumina-toughened (ATZ: ATZ, were compared subtractively 3Y-TZP (control: LAVA Plus, 3M Oral Care). Crystallographic analysis was conducted X-ray diffraction. Top surfaces cross-sections subsurface...
Nitrogen dioxide (NO2) is associated with mortality and many other adverse health outcomes. In 2021, the World Health Organization established a new NO2 air quality guideline (AQG) (annual average <10 μg/m3). However, burden of diseases attributable to long-term exposure above AQG unknown in China. oxide major pollutant populous cities, which are disproportionately impacted by NO2; this represents form environmental inequality. We conducted nationwide risk assessment premature deaths from...
Abstract Gestational exposure to ambient fine particles (PM 2.5 ) increases the risk of stillbirth, but related disease burden is unknown, particularly in low- and middle-income countries (LMICs). We combine state-of-the-art estimates on stillbirths, multiple exposure–response functions obtained from previous meta-analyses or derived by a self-matched case-control study 54 LMICs. 13,870 stillbirths 32,449 livebirths are extracted 113 geocoded surveys Demographic Health Surveys. Each...
ABSTRACT Clean air actions (CAAs) in China have been linked to considerable benefits public health. However, whether the beneficial effects of CAAs are equally distributed geographically is unknown. Using high-resolution maps distributions major pollutants (fine particulate matter [PM2.5] and ozone [O3]) population, we aimed track spatiotemporal changes health impacts from, geographic inequality embedded in, reduced exposures PM2.5 O3 from 2013 2020. We used a method established by Global...
BackgroundIn 2021, WHO suggested new target concentration limits for long-term exposure to ambient ozone. However, the harmful effects of ozone on vulnerable children have not been sufficiently studied. We aimed evaluate association between and mortality in younger than 5 years (hereafter denoted under-5 mortality) low-income middle-income countries (LMICs) estimate this burden 97 LMICs.MethodsBy combining information from 128 Demographic Health Surveys, we evaluated survival status more 1·2...
Abstract Most circulating tumor DNA (ctDNA) assays are designed to detect recurrent mutations. Pediatric sarcomas share few mutations but rather characterized by translocations and copy-number changes. We applied Cancer Personalized Profiling deep Sequencing (CAPP-Seq) for detection of found in the most common pediatric sarcomas. also ichorCNA combined off-target reads from our hybrid capture simultaneously alterations (CNA). analyzed 64 prospectively collected plasma samples 17 patients...
Photopolymer resins are widely used in the production of dental prostheses, but their mechanical properties require improvement. We evaluated effects different zirconia filler contents and printing directions on photopolymer resin. Three-dimensional (3D) was to fabricate specimens using composite photopolymers with 0 (control), 3, 5, 10 wt.% filler. Two for fabricating rectangular (25 mm × 2 mm) disk-shaped (φ10 were used, 0° 90°. Three-point bending tests performed determine flexural...
There is limited research on the influence of different sintering temperatures properties highly translucent zirconia ceramics. This study demonstrated translucency, crystallographic structure, biaxial flexural strength, microstructure, and low-temperature degradation (LTD) three grades, i.e., 3 mol% yttria-stabilized tetragonal polycrystals (3Y-TZP), 4 yttria-partially-stabilized (4Y-PSZ), 5 yttria-PSZ (5Y-PSZ). The specimens were characterized using colorimetry, X-ray diffraction, scanning...
Highly translucent zirconia (TZ) is frequently used in dentistry. The properties of several highly materials available the market require an in-depth understanding. In this study, we assessed translucency, crystalline phase, mechanical properties, and microstructures three newly developed (Zpex 4. m, 4 mol% yttria-stabilized zirconia: 4YSZ; Zpex Smile.m, 5YSZ; ZR Lucent ULTRA, 6YSZ). translucency parameter (TP) was analyzed using CIELAB system. X-ray diffraction conducted for phase analysis,...
Quantum computing is becoming a revolutionary technology with vast applicability across many sectors, including medicine. As the medical science in front of more complicated problems involving drug discovery, genomics, and disease modeling, application quantum opens doors to new opportunities. This paper also discusses specific uses healthcare domain: genomics genetics, imaging, biomolecular simulations, public health. The research embraces how algorithms improve genome data, diagnosis focus...
Abstract Owing to the tooth‐centered nature of most oral diseases, tooth‐centric radial plane cone‐beam computed tomography (CBCT) depicts anatomical and pathological features along long axis tooth, serving as a crucial imaging modality in diagnosis, treatment planning, prognosis multiple diseases. However, reconstructing these standard planes from CBCT is labor‐intensive, time‐consuming, error‐prone due variances multi‐center discrepancies. This study proposes an expertise‐inspired...
The U-shaped association between health outcomes and ambient temperatures has been extensively investigated. However, such analyses cannot fully estimate the mortality burden of climate change because features (e.g., minimum temperature) vary with human adaptation; thus, they are not generalizable to different locations. In this study, we assumed that humans could adapt regular temperature variations; thus examined all-cause attributable anomaly (TA), an indicator widely utilized in science...