Ishan Khosla

ORCID: 0009-0009-1441-8102
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About
Contact & Profiles
Research Areas
  • Spine and Intervertebral Disc Pathology
  • Musculoskeletal pain and rehabilitation
  • Anesthesia and Pain Management
  • Cervical and Thoracic Myelopathy
  • Orthopaedic implants and arthroplasty
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • Medical Imaging and Analysis
  • RNA Research and Splicing
  • Spinal Fractures and Fixation Techniques
  • Spinal Hematomas and Complications
  • Hip and Femur Fractures
  • Pelvic and Acetabular Injuries
  • Cardiovascular Function and Risk Factors
  • Clinical practice guidelines implementation
  • Economic and Technological Innovation
  • Surgical site infection prevention
  • Orthopedic Infections and Treatments
  • Infectious Diseases and Tuberculosis
  • Pulmonary Hypertension Research and Treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Medical Imaging and Pathology Studies
  • Chronic Disease Management Strategies

Rush University Medical Center
2023-2024

Rutgers, The State University of New Jersey
2021

University of Petroleum and Energy Studies
2021

Introduction: Patients with a prolonged preoperative symptom duration (PSD) in the setting of cervical disk herniation (DH) may suffer inferior outcomes after surgical intervention. Comparison between anterior diskectomy and fusion (ACDF) versus arthroplasty (CDA) this at-risk population has not yet been conducted. Methods: undergoing ACDF or CDA for DH PSD > 180 days were selected. Six-week (6W) final follow-up (FF) patient-reported outcome measures (PROMs) as well magnitude...

10.5435/jaaos-d-23-00655 article EN Journal of the American Academy of Orthopaedic Surgeons 2024-04-30

To evaluate the effect of Veterans RAND 12-item health survey mental composite score (VR-12 MCS) on postoperative patient-reported outcome measures (PROMs) after undergoing lateral lumbar interbody fusion.

10.14245/ns.2346730.365 article EN cc-by-nc Neurospine 2024-01-29

Abstract Homozygous mutations in the gene encoding scavenger mRNA-decapping enzyme, DcpS, have been shown to underlie developmental delay and intellectual disability. Intellectual disability is associated with both abnormal neocortical development mRNA metabolism. However, role of DcpS its decapping activity neuronal unknown. Here, we show that human neurons derived from patients a mutation compromised differentiation neurite outgrowth. Moreover, developing mouse neocortex, required for...

10.1093/cercor/bhab302 article EN Cerebral Cortex 2021-08-03

Study Design: Retrospective review. Objective: To evaluate mental health influence on minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) patients. Summary of Background Data: Poor has been postulated to indicate inferior patient perceptions surgical outcomes in spine literature. Few studies have assessed as a dynamic metric throughout the perioperative period. Methods: A single-surgeon database was retrospectively searched for patients who underwent primary, elective...

10.1097/bsd.0000000000001653 article EN Clinical Spine Surgery A Spine Publication 2024-06-27

Abstract Homozygous mutations in the gene encoding scavenger mRNA-decapping enzyme, DcpS, have been shown to underlie developmental delay and intellectual disability. Intellectual disability is associated with both abnormal neocortical development mRNA metabolism. However, role of DcpS its decapping activity neuronal unknown. Here, we show that human neurons derived from patients a mutation compromised differentiation neurite outgrowth. Moreover, developing mouse neocortex, required for...

10.1101/2021.05.10.443481 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-05-11
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