A5082114780- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Cervical and Thoracic Myelopathy
- Spinal Fractures and Fixation Techniques
- Medical Imaging and Analysis
- Anesthesia and Pain Management
- Orthopaedic implants and arthroplasty
- Spinal Hematomas and Complications
- Pelvic and Acetabular Injuries
- Scoliosis diagnosis and treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Clinical practice guidelines implementation
- COVID-19 and healthcare impacts
- Pregnancy-related medical research
- Hip and Femur Fractures
- Management of metastatic bone disease
- Surgical Simulation and Training
- Health Literacy and Information Accessibility
- Cancer Diagnosis and Treatment
- Orthopedic Surgery and Rehabilitation
- Dermatological and COVID-19 studies
- Health Education and Validation
- Bone Tumor Diagnosis and Treatments
- Diabetic Foot Ulcer Assessment and Management
- Surgical site infection prevention
Rush University Medical Center
2018-2024
Accreditation Council for Graduate Medical Education
2023-2024
Medical Education Institute
2023-2024
Cedars-Sinai Medical Center
2023
University of California, San Diego
2023
Cervical Spine Research Society
2023
Zimmer Biomet (United States)
2023
Rush University
2022-2023
University of Miami
2014-2017
University of Southern California
2015-2017
Glioblastomas multiforme (GBM) are the most frequently occurring malignant brain cancers. Treatment for GBM consists of surgical resection and subsequent adjuvant radiation therapy chemotherapy. Despite this, patient survival is limited to 12-15 months, researchers continually trying develop improved options. Insulin-like growth factor 2 mRNA-binding protein (Imp2) known be upregulated in many cancers regulate signaling activity insulin-like (IGF2). However, relatively little about its role...
Cisplatin is regularly used in the treatment of lung cancer.However, its efficacy limited because drug resistance.In this study, we found that Akt expression and activity was increased cancer cells with acquired cisplatin resistance (A549/DDP H460/DDP cells) when compared to their parental cells.Inhibition phosphatidylinositol 3-kinase (PI3K)/Akt kinase by natural inhibitor, Wortmannin, could sensitize DDP-resistant DDP reverse resistance.Combination Wortmannin capable increasing mortality...
Glioblastoma multiforme (GBM) is the most aggressive brain tumour type in humans. Its poor prognosis largely attributed to its invasiveness and high rate of recurrence. Recurring GBM commonly resistant chemotherapeutic drugs, making it specially difficult treat. Recent studies have revealed that matricellular glycoprotein SPOCK1 be upregulated several cancer types specifically expressed invasive GBM, but not other non-invasive tumour, which prompted us study mechanism action invasion,...
Assessment of joint range motion (ROM) is an accepted evaluation disability as well indicator recovery from musculoskeletal injuries. Many goniometric techniques have been described to measure ROM, with variable validity due inter-rater reliability. In this report, we assessed the photograph-based goniometry in measurement ROM and its reliability compared it two other commonly used techniques.We examined three methods for measuring upper extremity: manual (MG), visual estimations (VE),...
Study Design. Retrospective cohort. Objective. We evaluate the correlation of Patient-Reported Outcomes Measurement Information System for physical function (PROMIS-PF) with legacy patient-reported outcome measures (PROMs) in patients undergoing minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) up to 2 years postoperatively. Summary Background Data. PROMIS-PF has not been validated past 6 months following MIS TLIF. Methods. A surgical registry was retrospectively reviewed...
Prospective, randomized controlled trial.The aim was to compare perioperative and radiographic outcomes between stand-alone anterior plated 1 2-level cervical discectomy fusion (ACDF).ACDF with interbody spacer separate plate/screw construct (PLATE) may be associated a higher incidence of postoperative dysphagia, increased operative time, other complications. Therefore, some have opted utilize an cage integrated screws no plate (CAGE) good results.Patients 1-level degenerative disease were...
Abstract Background The COVID‐19 pandemic has impacted spine care around the globe. Much uncertainty remains regarding immediate and long‐term future of education in this era. Study design Cross‐sectional, international study surgeons. Methods A multi‐dimensional survey was distributed to surgeons world. total 73 questions were asked demographics, observations, personal impact, effect on education, adoption telemedicine, anticipated challenges moving forward. Multivariate analysis performed...
Adjacent segment disease (ASDz) is a potential complication following lumbar spinal fusion. A common nomenclature based on etiology and ASDz type does not exist needed to assist with clinical prognostication, decision making, management.The objective of this study was develop an etiology-based classification system for fusion.We conducted retrospective chart review 65 consecutive patients who had undergone both fusion performed by single surgeon subsequent procedure ASDz. We established the...
To evaluate preoperative disability's influence on patient-reported outcomes (PROs) following surgery for degenerative spondylolisthesis (DS).
Introduction: Patients with a prolonged preoperative symptom duration (PSD) in the setting of cervical disk herniation (DH) may suffer inferior outcomes after surgical intervention. Comparison between anterior diskectomy and fusion (ACDF) versus arthroplasty (CDA) this at-risk population has not yet been conducted. Methods: undergoing ACDF or CDA for DH PSD > 180 days were selected. Six-week (6W) final follow-up (FF) patient-reported outcome measures (PROMs) as well magnitude...
Retrospective Review.