A5100318880- Drug Transport and Resistance Mechanisms
- Methemoglobinemia and Tumor Lysis Syndrome
- Protein Interaction Studies and Fluorescence Analysis
- RNA Research and Splicing
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Geomagnetism and Paleomagnetism Studies
- Gut microbiota and health
- Machine Learning in Bioinformatics
- Food Quality and Safety Studies
- Plant Toxicity and Pharmacological Properties
- Immune cells in cancer
- Biomedical Text Mining and Ontologies
- Magnetic and Electromagnetic Effects
- Toxic Organic Pollutants Impact
- Privacy, Security, and Data Protection
- Protein Hydrolysis and Bioactive Peptides
- Berberine and alkaloids research
- Per- and polyfluoroalkyl substances research
- Iron oxide chemistry and applications
- Natural Language Processing Techniques
- Human Mobility and Location-Based Analysis
- Pharmacological Effects of Natural Compounds
- Bee Products Chemical Analysis
- Plant tissue culture and regeneration
University of South China
2024
Second Affiliated Hospital of Nanchang University
2022
Nanchang University
2022
Peking University Shenzhen Hospital
2011-2021
China Industrial Control Systems Cyber Emergency Response Team
2020
National Earthquake Response Support Service
2020
Anhui Agricultural University
2018-2019
Mudanjiang Medical University
2015
Iowa State University
2011-2012
Wayne State University
2011
The herbicide atrazine is widely used across the globe, which a great concern. To investigate its potential toxicity in human body, serum albumin (HSA) was selected as model protein. interaction between and HSA investigated using steady-state fluorescence spectroscopy, synchronous UV-Vis three-dimensional (3D) spectroscopy circular dichroism (CD) spectroscopy. intrinsic of quenched by through static quenching mechanism. Fluorescence spectra at two excitation wavelengths (280 295 nm) showed...
Glioblastomas multiforme (GBM) are the most frequently occurring malignant brain cancers. Treatment for GBM consists of surgical resection and subsequent adjuvant radiation therapy chemotherapy. Despite this, patient survival is limited to 12-15 months, researchers continually trying develop improved options. Insulin-like growth factor 2 mRNA-binding protein (Imp2) known be upregulated in many cancers regulate signaling activity insulin-like (IGF2). However, relatively little about its role...
To protect against oxidative stress‐induced apoptosis in lens epithelial cells is a potential strategy preventing cataract formation. The present study aimed at studying the protective effect and underlying mechanisms of p ‐coumaric acid ( ‐CA) on hydrogen peroxide‐ (H 2 O ‐) induced human (HLE) (SRA 01–04). Cells were pretreated with ‐CA concentration 3, 10, 30 μ M before treatment H (275 M). Results showed that pretreatment significantly protected ‐induced cell death dose‐dependent manner,...
Verticinone, an isosteroidal alkaloid separated from Bulbus Fritillaria (Chinese name "Bei-mu"), was evaluated for its analgesic activities in murine models of inflammatory and neuropathic pain. It shown that oral administarion verticinone could significantly inhibit acetic acid-induced writhing response a dose-dependent way, the inhibition 3 mg/kg 66.2%, which approximately higher than 200 aspirin. In formalin test, high dose (3 mg/kg) nociceptive both phases, but lower (1.5 only second...
Surface sensitive X-ray scattering and spectroscopic studies have been conducted to determine structural properties of Mms6, the protein in Magnetospirillum magneticum AMB-1 that is implicated as promoter magnetite nanocrystals growth. pressure versus molecular area isotherms indicate Mms6 forms stable monolayers at aqueous/vapor interface are strongly affected by ionic conditions subphase. Analysis reflectivity from shows conformation depends on surface presence ions solutions, particular...
To explore the effect of probiotics combined with budesonide and ipratropium bromide in treatment chronic obstructive pulmonary disease (COPD) on lung function gut microbiota. This was a retrospective study prospectively collected clinical data 118 patients COPD admitted to our hospital between January 2020 December 2022. According records, 59 received irpratropium (control group), (observation group). The function, inflammatory factor levels, airway remodeling, microbiota before after were...
Dilated cardiomyopathy (DCM) is a type of that can easily cause heart failure and has high mortality rate. Therefore, there an urgent need to study the underlying mechanism action dilated cardiomyopathy. In present study, we aimed explore potential miRNA-mRNA pairs drugs related DCM. The Microarray data were collected from Gene Expression Omnibus (GEO) database. Bioinformatics analysis differentially expressed miRNAs mRNAs in each microarray obtained. target genes obtained miRWalk 2.0...
Prediction of protein secondary structures is an important problem in bioinformatics and has many applications. Successful structure predictions provide a starting point for direct tertiary modelling, also can significantly improve sequence analysis sequence-structure threading aiding function determination. Now prediction methods routinely achieve accuracy (Q3) about 70%. We believe this could be further improved by using hybrid method as essential part the process. In article, SVM(HSVM)...
The gut microbiota is very important in the initiation, progression, and dissemination of cancer, regulation has been employed as a novel strategy to enhance effect immunotherapy. Adiponectin (APN), an adipocyte-derived hormone, plays vital role regulating immune response innate cells. deficiency APN inhibits rhabdomyosarcoma growth. However, whether this function associated with remains unknown. To investigate, we performed 16S ribosomal RNA (rRNA) gene sequencing on fecal microbiome...
Hans Christian von Baeyer The year 1900 is a singularly significant in science, celebrating as it does the birth of both quantum mechanics and molecular biology. key papers Max Planck will, course, be familiar to most physicists. In biology, however, took three researchers working independently Amsterdam, Berlin Vienna rediscover Mendel's laws heredity, which he had originally published 1866 transactions Scientific Society City Bruenn (now Bron) present-day Czech Republic.
With the vigorous development of Internet Things (IoT) industry, cybersecurity issues IoT are emerging. Putting into priorities has become a common practice in many countries around world. In this paper, we expound on relevant strategies, regulations, standards, guidelines, and other policy documents released by domestic foreign governments recent years. Firstly, paper focuses content characteristics security policies US, EU, UK, Australia, then summarizes China's policies. Based these,...