A5078476868- Molecular Sensors and Ion Detection
- Sulfur Compounds in Biology
- Protein Interaction Studies and Fluorescence Analysis
- Drug Transport and Resistance Mechanisms
- Pharmaceutical and Antibiotic Environmental Impacts
- Electrochemical sensors and biosensors
- Pesticide and Herbicide Environmental Studies
- Advanced biosensing and bioanalysis techniques
- Polymer-Based Agricultural Enhancements
- Analytical Chemistry and Chromatography
- Methemoglobinemia and Tumor Lysis Syndrome
- Advanced Photocatalysis Techniques
- Folate and B Vitamins Research
- Pesticide Residue Analysis and Safety
- Insect and Pesticide Research
- Analytical chemistry methods development
- Advanced oxidation water treatment
- Analytical Chemistry and Sensors
- Antibiotics Pharmacokinetics and Efficacy
- Protein purification and stability
- Redox biology and oxidative stress
- Lanthanide and Transition Metal Complexes
- Carbon and Quantum Dots Applications
- Luminescence and Fluorescent Materials
- Adsorption and biosorption for pollutant removal
Anhui Polytechnic University
2022-2025
Anhui Agricultural University
2016-2022
Henan Agricultural University
2019-2020
Hefei University
2019
The University of Texas Health Science Center at San Antonio
2015
Beijing Red Cross Blood Center
1992
The herbicide atrazine is widely used across the globe, which a great concern. To investigate its potential toxicity in human body, serum albumin (HSA) was selected as model protein. interaction between and HSA investigated using steady-state fluorescence spectroscopy, synchronous UV-Vis three-dimensional (3D) spectroscopy circular dichroism (CD) spectroscopy. intrinsic of quenched by through static quenching mechanism. Fluorescence spectra at two excitation wavelengths (280 295 nm) showed...
Cu2+ is an essential trace element for the organism, but its excess can also cause irreversible damage to organism. As such, a "Turn-Off" fluorescent probe DPAP specific detection of was successfully constructed. exhibits large Stokes shift (120 nm), fast reaction speed (1 min), low limit (15.2 nM), toxicity, and good cell permeability. quenches fluorescence by blocking intramolecular charge transfer process achieve has been confirmed HRMS, 1H NMR DFT calculations. Excitingly, five-cycle...
Sulfonamide antibiotics (SAs) are widely used in medicine, animal husbandry and aquaculture, excessive intake of SAs may pose potential toxicity to organisms. The toxicological mechanisms two classical SAs, sulfamerazine (SMR) sulfamethoxazole (SMT), were investigated by molecular docking, DFT multi-spectroscopic techniques using HSA BSA as model proteins. quenching HSA/BSA endogenous fluorescence SMR was higher than that SMT due the stronger binding effect pyrimidine ring on compared...
Fluorescence-labeling technology has been widely used for rapid detection of pesticides in agricultural production. However, there are few studies on the use this to investigate pesticide uptake and transport plants with fluorescent nanoparticle formulations. Here, we investigated uptake, transport, accumulation metabolism imidacloprid loaded mesoporous SiO2 nanoparticles (Im@FL-MSNs) tomato plants, compared results application granular formulation. The revealed that Im@FL-MSNs applied via...
Biothiols, such as cysteine (Cys), homocysteine (Hcy), and glutathione (GSH), play a key role in an extensive range of physiological processes biological functions. Therefore, the selective sensitive detection intracellular thiols is important for revealing cellular function. In this study, ethyl 2-(4-(acryloyloxy)-3-formylphenyl)-4-methylthiazole-5-carboxylate (NL-AC) was designed synthesized colorimetric ratiometric fluorescent probe that can be utilized to rapidly, sensitively selectively...
Prothioconazole (PTC) has been widely utilized for plant fungal disease control, but its metabolite prothioconazole-desthio (PTC-d) exhibits reproductive toxicity. In the present study, carbon quantum dot (CQD)-modified fluorescent double-hollow shelled mesoporous silica nanoparticles (FL-MSNs) loaded with PTC, referred to as PTC@FL-MSNs, were constructed an average size of 369 nm and a loading capacity 28.1 wt %, which could increase antifungal efficiency PTC. addition, upright fluorescence...
As an inorganic small molecule pollutant, the toxicity and potential carcinogenicity of hydrazine (N2H4) are increasing concern. In this work, A water-soluble fluorescent probe (OCYB) based on intramolecular charge transfer (ICT) mechanism for detection was designed synthesized. Taking advantage 4-bromobutyryl as recognition group, high selectivity OCYB to N2H4 confirmed by steady-state fluorescence spectroscopy. The limit (LOD) calculated be 78 nM in DMSO-HEPES (pH 7.4) system. verified...
The heavy application of neonicotinoid insecticides in agricultural production has burdened the environment. In present study, interactions two imidacloprid and thiamethoxam with dissolved organic matter (DOM) were investigated by spectroscopic techniques, molecular modeling, density functional theory (DFT) calculations. static mechanism quenching endogenous fluorescence DOM was assessed through time-resolved analyses. During binding process, a protein-like substance binds later than...