A5003293617- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Synthesis and Catalytic Reactions
- Asymmetric Synthesis and Catalysis
- Drug Transport and Resistance Mechanisms
- Protein Interaction Studies and Fluorescence Analysis
- Molecular Sensors and Ion Detection
- Ion channel regulation and function
- Sulfur Compounds in Biology
- Insect and Pesticide Research
- Asymmetric Hydrogenation and Catalysis
- Synthesis of β-Lactam Compounds
- Fungal Plant Pathogen Control
- Analytical Chemistry and Chromatography
- Bioactive Compounds and Antitumor Agents
- Synthetic Organic Chemistry Methods
- Folate and B Vitamins Research
- Plant chemical constituents analysis
- Synthesis and Biological Evaluation
- Catalytic C–H Functionalization Methods
- Orthopedic Surgery and Rehabilitation
- Metal-Organic Frameworks: Synthesis and Applications
- Alzheimer's disease research and treatments
- Pesticide Residue Analysis and Safety
- Cyclopropane Reaction Mechanisms
Henan Agricultural University
2016-2025
Wuhan College
2024
Wuhan City College
2024
Inner Mongolia People's Hospital
2019-2021
Inner Mongolia University for Nationalities
2021
China Agricultural University
2009-2017
Anhui Agricultural University
2016-2017
Zhengzhou University
2016
Beijing University of Agriculture
2009
Droplet deposition on superhydrophobic surfaces has been a great challenge owing to the shortness of impact contact time. Despite recent research progress regarding flat surfaces, improving ubiquitous wired and curved leaves remains challenging as their surface structures promote asymmetric impacts, thereby shortening times increasing likelihood droplet splitting. Here, we propose strategy solve problems based an analysis dynamics rational selection additives. Combining prominent extension...
Phosphine-catalyzed [3+2] and [4+3]annulation reactions of C,N-cyclic azomethine imines with allenoates have been developed to give a variety pharmaceutically attractive tetrahydroisoquinoline derivatives in moderate excellent yields. The two distinct reaction pathways, [4+3]cyclization, depend on the nature nucleophilic phosphine allenoate. Generally, for α-alkylallenoates, always proceed [3 +2]cyclization as major pathway no matter what was used; α-ArCH2-substituted allenoates, controlled...
The more dipoles, the merrier: An asymmetric [3+3] cycloaddition of azomethine ylides derived from imines 1 with 2 in presence a chiral ferrocenylphosphine–copper catalyst afforded highly functionalized heterocyclic products 3 high yield excellent enantio- and diastereoselectivity (see scheme; DBU=1,8-diazabicyclo[5.4.0]undec-7-ene). 1,3-dipolar reaction partners can be readily prepared aldehydes. As service to our authors readers, this journal provides supporting information supplied by...
An iridium photoredox catalyst in combination with phenanthroline-supported palladium catalyzes decarboxylative alkenylation of tertiary and secondary aliphatic carboxylic acids vinyl arenes to deliver β-alkylated styrenes Z-selectivity. A broad scope acids, including amino exhibit as amenable substrates, external oxidant is not required. The reaction proceeds by synergistic utilization both energy-transfer electron-transfer reactivity merging palladium-catalyzed hydride elimination insertion.
Biothiols, such as cysteine (Cys), homocysteine (Hcy), and glutathione (GSH), play a key role in an extensive range of physiological processes biological functions. Therefore, the selective sensitive detection intracellular thiols is important for revealing cellular function. In this study, ethyl 2-(4-(acryloyloxy)-3-formylphenyl)-4-methylthiazole-5-carboxylate (NL-AC) was designed synthesized colorimetric ratiometric fluorescent probe that can be utilized to rapidly, sensitively selectively...
Abstract BACKGROUND Suitable nano‐pesticide carriers play a crucial role in enhancing the utilization efficiency of pesticides. Among these, mesoporous silica nanoparticles (MSNs) are most promising candidates for large‐scale and safe pesticide applications. RESULTS In present work, functionalized MSNs were demonstrated to be effective mitochondrial‐targeted delivering strobilurin fungicides (mitochondrial respiratory chain inhibitors). bi‐functionalized with carboxymethyl chitosan (CMC),...
Abstract Meeting the challenge : The zinc/amino alcohol catalyzed enantioselective addition of terminal alkynes to aldehydes is effective with both phenylacetylene and methyl propiolate, leading chiral secondary propargyl alcohols very high enantioselectivity (see scheme). magnified image
Abstract The phosphine-catalyzed [3 + 2] and 3] annulation reactions of azomethine imines ethyl 2-butynoate were developed, providing 1,2-dinitrogen-containing heterocycles tetrahydropyrazolopyrazolones tetrahydropyrazolopyridazinones in moderate to good yields.
The heavy application of neonicotinoid insecticides in agricultural production has burdened the environment. In present study, interactions two imidacloprid and thiamethoxam with dissolved organic matter (DOM) were investigated by spectroscopic techniques, molecular modeling, density functional theory (DFT) calculations. static mechanism quenching endogenous fluorescence DOM was assessed through time-resolved analyses. During binding process, a protein-like substance binds later than...
Heterocyclensammlung: Die asymmetrische [3+3]-Cycloaddition von Azomethinyliden, die sich den Iminen 1 ableiten, mit Azomethiniminen 2 in Gegenwart eines chiralen Ferrocenylphosphan-Kupferkatalysators liefert hoch funktionalisierte heterocyclische Produkte 3 hoher Ausbeute exzellenter Enantio- und Diastereoselektivität (siehe Schema; DBU=1,8-Diazabicyclo[5.4.0]undec-7-en). 1,3-dipolaren Reaktionspartner können leicht aus Aldehyden hergestellt werden. As a service to our authors and readers,...
Biothiols such as cysteine (Cys) and homocysteine (Hcy) are essential biomolecules participating in molecular physiological processes an organism. However, their selective detection remains challenging. In this study, ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate (NL) was synthesized a ratiometric fluorescent probe for the rapid of Cys Hcy over glutathione (GSH) other amino acids. The fluorescence intensity presence Cys/Hcy increased about 3-fold at concentration 20...
Autophagy is an evolutionarily conserved mechanism in eukaryotes with roles development and the virulence of plant fungal pathogens. However, few reports on autophagy oomycete species have been published. Here, we identified 26 autophagy-related genes (ATGs) belonging to 20 different groups Phytophthora sojae using a genome-wide survey, core ATGs oomycetes were used construct preliminary pathway model. Expression profile analysis revealed that these are broadly expressed majority them...
1,3-Dipolar cycloaddition reactions are one of the most important methods to obtain diverse heterocycles with novel skeletons. We herein report Brønsted acid or Lewis catalyzed [3+3] azomethine imines nonstabilized ylide generated in situ from an <i>N</i>-benzyl precursor, providing a clean and facile access bicyclic N-heterocycles moderate good yields for further biological testing. Also, protocol developed achieved formation C–C C–N bonds simultaneously single step.
Phasmatodea represents an order of hemimetabolous insects. This group includes species with extreme forms masquerade crypsis, whereby they imitate twigs, bark, lichen, moss, and leaves. In this study, we sequenced annotated three mitochondrial genomes (mitogenomes) from Phasmatodea. The lengths the novel mitogenomes range 14,162 bp to 15,879 bp. gene content organization correspond those inferred for ancestral insect. We conducted phylogenetic analyses together existing polyneopterans...
In the present study, 3-(fluorobenzylideneamino)-6-chloro-1-(3,3-dimethylbutanoyl)-phenyl-2,3-dihydroquinazolin-4(1H)-one (FDQL) derivatives have been designed and synthesized to study interaction between fluorine substituted dihydroquinazoline with human serum albumin (HSA) using fluorescence, circular dichroism Fourier transform infrared spectroscopy. The results indicated that FDQL could bind HSA, induce conformation secondary structure changes of quench intrinsic fluorescence HSA through...