- Tea Polyphenols and Effects
- Renal and related cancers
- Alzheimer's disease research and treatments
- Plant nutrient uptake and metabolism
- Food Quality and Safety Studies
- Plant Molecular Biology Research
- Nicotinic Acetylcholine Receptors Study
- Renal cell carcinoma treatment
- Phytochemicals and Antioxidant Activities
- Tryptophan and brain disorders
- Fermentation and Sensory Analysis
- Vagus Nerve Stimulation Research
- Genomics, phytochemicals, and oxidative stress
- Epigenetics and DNA Methylation
- Liquid Crystal Research Advancements
- Birth, Development, and Health
- Plant Gene Expression Analysis
- Plant Stress Responses and Tolerance
- Potato Plant Research
- Berberine and alkaloids research
- NF-κB Signaling Pathways
- Inflammasome and immune disorders
- Fibroblast Growth Factor Research
- Allelopathy and phytotoxic interactions
- Plant responses to elevated CO2
The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture
2025
Sichuan Agricultural University
2020-2024
Guangzhou University of Chinese Medicine
2020-2024
University of Hawaiʻi at Mānoa
2020-2024
Army Medical University
2021-2024
Xinqiao Hospital
2021-2024
Wuhan University
2024
Henan Agricultural University
2024
Wuhan College
2024
Science and Technology Department of Sichuan Province
2023
'Ziyan' is a novel anthocyanin-rich tea cultivar with dark purple young shoots. However, how its anthocyanin accumulation affected by environmental factors, such as ultraviolet (UV), remains unclear. In this study, we observed that UV light treatments stimulated in leaves, and further analyzed the underlying mechanisms at gene expression enzyme activity levels. addition, catechins chlorophyll contents of shoots under different were also changed. The results showed total anthocyanins three...
BACKGROUND Scientifically sound and reasonable care strategies in surgical nursing play a crucial role facilitating postoperative recovery preventing complications. This study focused on the application of quantitative assessment to care. By quantitatively analyzing effects interventions, we explored their feasibility effectiveness at improving quality reducing incidence provides scientific basis for practice offers new insights into management with significant clinical value. AIM To analyze...
In organ regeneration, progenitor and stem cells reside in their native microenvironment, which provides dynamic physical chemical cues essential to survival, proliferation, differentiation. However, the types of that form microenvironment for renal (RPCs) have not been clarified. Here, single-cell sequencing zebrafish kidney reveals fabp10a as a principal marker interstitial (RICs), can be specifically labeled by GFP under control promoter fabp10a:GFP transgenic zebrafish. During nephron...
Isoorientin has anti-inflammatory effects; however, the mechanism remains unclear. We previously found isoorientin is an inhibitor of glycogen synthase kinase 3β (GSK3β) in vitro. Overactivation GSK3β associated with inflammatory responses. inactivated by phosphorylation at Ser9 (i.e., p-GSK3β). Lithium chloride (LiCl) inhibits and also increases p-GSK3β (Ser9). The present study investigated effect via regulation lipopolysaccharide- (LPS-) induced RAW264.7 murine macrophage-like cells...
Abstract High mountain tea (HT) is widely acknowledged as an essential resource of high‐quality due to its adaptation superior ecological environments. In this study, the sensory (aroma and taste) safety (heavy metals pesticide residues) characteristics HT were characterized through evaluation, gas chromatography–mass spectrometry (GC‐MS), liquid (LC‐MS), flavor activity value, risk factor analysis. The results elucidated that aroma tender green, accompanied by sweet slight chestnut. A total...
Cadmium (Cd) is highly toxic and not easily degradable. It damages plant growth results in large-scale economic losses. The present study explored the feasibility of using melatonin to alleviate Cd toxicity, reduce accumulation tea seedlings cultivated Cd-contaminated soil. Exogenous melatonin, especially at 150 μM, promoted seedling under stress, increased photosynthetic pigment by 16% soluble protein content 5%. Furthermore, effectively activities superoxide dismutase (SOD), peroxidase...
Currently, the effects of differences between day and night temperatures (DIFs) on tea plant are poorly understood. In order to investigate influence DIFs growth, photosynthesis, metabolite accumulation plants, plants were cultivated under 5 °C (25/20 °C, light/dark), 10 (25/15 15 (25/10 light/dark). The results showed that growth rate new shoots decreased with an increase in DIFs. There was a downward trend photosynthesis among treatments, as evidenced by lowest net photosynthetic total...
Abstract Lung cancer is the leading cause of deaths worldwide, with a high morbidity and less than 20% survival rate. Therefore, new treatment strategies drugs are needed to reduce mortality patients lung cancer. α7 nicotinic acetylcholine receptor (α7 nAChR), as nicotine its metabolites, potential target for treatment. Our previous studies revealed that sinomenine plays anti-inflammation roles via nAChR down-regulates expression this receptor, thus increasing inflammatory response. Hence,...
Nitrogen (N) is a key regulator in the growth of tea plants and synthesis amino acids (AAs) related secondary metabolites, thus affecting yield quality leaves. Increased N fertilization significantly improves plants, but applying excess nitrogen wastes resources causes pollution problems. Herein, we employed morphological, physiological, metabolomic, RNA-seq methods to study response ‘Ziyan’ roots high N. High supply induced an increase arginine (Arg), asparagine (Asn), glutamine (Gln)...
Organ regeneration necessitates precise coordination of accelerators and brakes to restore organ function. However, the mechanisms underlying this intricate molecular crosstalk remain elusive. In study, level proenkephalin-A (PENK-A), expressed by renal proximal tubular epithelial cells, decreases significantly with loss tubules increased at termination phase zebrafish kidney regeneration. Notably, change contrasts role hydrogen peroxide (H2O2), which acts as an accelerator in Through...
(1) Background: Anthocyanins, the main pigments in plants, are influenced by both temperature and photoperiod. However, specific mechanisms underlying anthocyanin accumulation tea plants response to these two environmental factors remain unclear. (2) Methods: This study subjected potted ‘Ziyan’ four types of day-length treatments (HL (28 °C, 16 h), HS 8 LL (18 LS h)), then conducted targeted metabolomic transcriptomic analyses samples. (3) Results: Long photoperiods low temperatures promoted...
Geniposide is a bioactive iridoid glucoside derived from <em>Gardenia jasminoides</em> that has proven anti‑inflammatory effects against acute lung injury. The aim of this study was to determine whether geniposide could protect pulmonary arterial smooth muscle cells (PASMCs) lipopolysaccharide (LPS)‑induced injury and explore the participation α7 nicotinic acetylcholine receptor (α7nAChR), which previously reported suppress pro‑inflammatory cytokine production in LPS‑stimulated macrophages....
The proximal convoluted tubule (PCT) of the kidney is a crucial functional segment responsible for reabsorption, secretion, and maintenance electrolyte water balance within renal tubule. However, there lack well-defined endogenous transgenic line studying PCT morphogenesis. By analyzing single-cell transcriptome data from adult zebrafish kidney, we have identified expression odd-skipped-related 2 (osr2, encodes an odd-skipped zinc-finger transcription factor) in PCT. To gain insight into...
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Although pruning contributes to the growth and development of new shoots, it is important note that potential yield tea varieties may differ after due genetic environmental factors. In this experiment, 20 different plants were used observe their for growth, shoot development, other phenotypic indexes pruning. The study aimed determine suitability each variety heavy It was concluded there obvious differences in tree strength varieties, with ‘Zhongcha 302’ exhibiting strongest ‘Emei Wenchun’...
Abstract As an important process for enhancing aroma of Wuyi rock tea, roasting has gradually been applied to the processing bud green tea (BGT). However, there is a lack comprehensive research on impact BGT aroma. This provides detailed analysis changes in perception and compounds during low‐temperature (105°C, 90 minutes) BGT. First, were studied using quantitative descriptive (QDA). The transformed from fresh chestnut like. Next, headspace solid‐phase microextraction–gas...
Isoorientin (ISO), a flavone C-glycoside, is glycogen synthase kinase 3β (GSK3β) substrate-competitive inhibitor. ISO has potential in treatment of Alzheimer's disease (AD). An excessive activation GSK3β can lead to neuroinflammation causing neuronal damage. Microglia cells, as resident immune cells the central nervous system, mediate neuroinflammation. Here, we studied effects on microglial alleviate
To evaluate the effects of perioperative care combined with cognitive training on neurological recovery and life ability in patients hypertensive intracerebral hemorrhage undergoing minimally invasive hematoma evacuation.