A5074325825- Molecular Biology Techniques and Applications
- Cancer Immunotherapy and Biomarkers
- Hepatocellular Carcinoma Treatment and Prognosis
- Immune Cell Function and Interaction
- Colorectal Cancer Treatments and Studies
- Phagocytosis and Immune Regulation
- Immune cells in cancer
- Cancer Genomics and Diagnostics
- Single-cell and spatial transcriptomics
Southwest Hospital
2024
Army Medical University
2020-2024
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
2024
University of Electronic Science and Technology of China
2024
Xinqiao Hospital
2020
City Of Hope National Medical Center
2002
Hepatocellular carcinoma (HCC) acquires an immunosuppressive microenvironment, leading to unbeneficial therapeutic outcomes. Hyaluronan-mediated motility receptor (HMMR) plays a crucial role in tumor progression. Here, we found that aberrant expression of HMMR could be predictive biomarker for the immune suppressive microenvironment HCC, but mechanism remains unclear. We established −/− liver cancer mouse model elucidate HMMR-mediated dysregulated “don't eat me” signal. knockout inhibited...