- Radiation Therapy and Dosimetry
- Virus-based gene therapy research
- Pain Management and Placebo Effect
- Radiopharmaceutical Chemistry and Applications
- Sarcoma Diagnosis and Treatment
- CAR-T cell therapy research
- Vaccine Coverage and Hesitancy
- COVID-19 Digital Contact Tracing
- Acupuncture Treatment Research Studies
- Misinformation and Its Impacts
- Effects of Radiation Exposure
- Complementary and Alternative Medicine Studies
Duke University
2022-2024
Study objectiveAcute musculoskeletal pain in emergency department (ED) patients is frequently severe and challenging to treat with medications alone. The purpose of this study was determine the feasibility, acceptability, effectiveness adding ED acupuncture acute episodes neck, back, extremities.MethodsIn pragmatic 2-stage adaptive open-label randomized clinical trial, Stage 1 identified whether auricular (AA; based on battlefield protocol) or peripheral (PA; needles head, extremities only),...
Importance Large segments of the US population’s primary health care access occurs in emergency departments (EDs). These groups have disproportionately high COVID-19 vaccine hesitancy and lower uptake. Objective To determine whether provision messaging platforms EDs increases acceptance uptake unvaccinated patients. Design, Setting, Participants This prospective cluster randomized clinical trial was conducted at 7 hospital 4 cities from December 6, 2021, to July 28, 2022. Noncritically ill...
The main deterrent to long-term space travel is the risk of Radiation Exposure Induced Death (REID). National Aeronautics and Space Administration (NASA) has adopted Permissible Levels (PELs) limit probability REID 3% for death due radiation-induced carcinogenesis. most significant contributor current estimates astronauts lung cancer. Recently updated cancer from Japan's atomic bomb survivors showed that excess relative by age 70 roughly four-fold higher in females compared males. However,...
The main deterrent to long-term space travel is the risk of Radiation Exposure Induced Death (REID). National Aeronautics and Space Administration (NASA) has adopted Permissible Levels (PELs) limit probability REID 3% for death due radiation-induced carcinogenesis. most significant contributor current estimates astronauts lung cancer. Recently updated cancer from Japan's atomic bomb survivors showed that excess relative by age 70 roughly fourfold higher in females compared males. However,...
Abstract Despite aggressive conventional therapy, many patients with high-risk soft-tissue sarcoma develop metastatic disease. To investigate mechanism(s) of metastasis, our lab has utilized genetically engineered mouse models. For example, we injected an adenovirus expressing Cre recombinase (adeno-Cre) into the gastrocnemius muscle LSL-KrasG12D; p53Flox/Flox (KP) mice to initiate high grade undifferentiated pleomorphic sarcomas, and after amputation approximately 40% lung metastasis. Using...