A5108817822- Forensic Toxicology and Drug Analysis
- COVID-19 epidemiological studies
- Data-Driven Disease Surveillance
- Influenza Virus Research Studies
- Psychedelics and Drug Studies
- Poxvirus research and outbreaks
- Cannabis and Cannabinoid Research
- Bacillus and Francisella bacterial research
- Opioid Use Disorder Treatment
- Air Quality and Health Impacts
- Analytical Chemistry and Chromatography
- Chemical Synthesis and Analysis
- Telemedicine and Telehealth Implementation
- Zoonotic diseases and public health
- Survey Methodology and Nonresponse
- Ethics in Clinical Research
- Infection Control and Ventilation
- Innovation Policy and R&D
- Fluorine in Organic Chemistry
- Statistical Methods in Epidemiology
- Rabies epidemiology and control
- COVID-19 and Mental Health
- Global Health Care Issues
- Focus Groups and Qualitative Methods
- Forecasting Techniques and Applications
European Monitoring Centre for Drugs and Drug Addiction
2017-2024
Bournemouth University
2024
UK Health Security Agency
2022-2024
Trinity College Dublin
2012
To analyse the transmission dynamics of monkeypox outbreak in UK, declared a Public Health Emergency International Concern July 2022.Contact tracing study, linking data on case-contact pairs and probable exposure dates.Case questionnaires from UK Security Agency (UKHSA), United Kingdom.2746 people with polymerase chain reaction confirmed virus between 6 May 1 August 2022.The incubation period serial interval infection using two bayesian time delay models-one corrected for censoring...
Etonitazene and related 2-benzylbenzimidazoles are potent analgetics invented in the research laboratories of Swiss pharmaceutical giant CIBA late 1950s. Though unprecedented structure distinguishes this class compounds from poppy-derived other synthetic analgetics, a range studies indicate that these drugs selective μ opioid receptor agonists possessing morphine-like pharmacotoxicological properties animals as well humans. Several unscheduled members synthetically readily accessible opioids...
Abstract In May 2022, individuals infected with the monkeypox virus were detected in UK without clear travel links to endemic areas. Understanding clinical characteristics and infection severity of mpox is necessary for effective public health policy. The study period this paper, from 1 st June 2022 30 th September included 3,375 that tested positive virus. posterior mean times hospital admission length stay 14.89 days (95% Credible Intervals (CrI): 13.60, 16.32) 7.07 CrI: 6.07, 8.23),...
With new synthetic cannabinoids (SCs) appearing on the European drug market every year, early warning systems are key to detect, monitor, and respond threats posed by them. The Union Early Warning System (EU EWS) implemented Monitoring Centre for Drugs Drug Addiction has monitored these substances since their first detection in 2008. Since then, national international responses have been implemented, aimed at tackling risks SCs. Throughout this time, SCs emerged containing diverse structural...
In May 2022, a cluster of mpox cases were detected in the UK that could not be traced to recent travel history from an endemic region. Over coming months, outbreak grew, with over 3000 total reported UK, and similar outbreaks occurring worldwide. These appeared linked sexual contact networks between gay, bisexual other men who have sex men. Following COVID-19 pandemic, local health systems strained, therefore effective surveillance for was essential managing public policy. However,...
Background Norovirus is a leading cause of acute gastroenteritis, adding to strain on healthcare systems. Diagnostic test reporting norovirus often delayed, resulting in incomplete data for real-time surveillance. Methods To nowcast the case burden generalised additive model (GAM), semi-mechanistic Bayesian joint process and delay “epinowcast”, structural time series (BSTS) including syndromic surveillance were developed. These models evaluated over weekly nowcasts using probabilistic...
Synthetic cannabinoids (SCs), often sold as "legal" replacements for cannabis, are the largest group of new psychoactive substances monitored by European Monitoring Centre Drugs and Drug Addiction (EMCDDA). Currently, close to 240 structurally heterogeneous SCs through Union (EU) Early Warning System, attributing consistent, informative, user-friendly names has been a challenge in past. Over time, several naming conventions have employed with aim making more easily recognizable non-chemists,...
The discrimination of a cross section cathinone regioisomers, sold as 'legal highs', using Raman spectroscopy, is reported here. Mephedrone and flephedrone were identified in high' products Irish head shops, their 2, 3 4-isomers synthesized reference standards. 3,4-methylenedioxy substituted cathinones, methylone, butylone methylenedioxypyrovalerone (MDPV), also highs' 2,3-isomers for comparison. In addition, alpha- beta-naphyrone synthesized. spectra all the isomers obtained far-red...
Abstract Background Seasonal influenza places a substantial burden annually on healthcare services. Policies during the COVID-19 pandemic limited transmission of seasonal influenza, making timing and magnitude potential resurgence difficult to ascertain its impact important forecast. Methods We have developed hierarchical generalised additive model (GAM) for short-term forecasting hospital admissions with positive test virus sub-regionally across England. The incorporates multi-level...
3β‐(4‐Fluorobenzoyloxy)tropane (3β‐FBT, fluorotropacocaine) was first reported by Finnish authorities to the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) via Early Warning System (EWS) in 2008 our own laboratory tentatively identified it 2010 several products purchased from head shops. Very little is known about this cocaine‐like drug and, as no reference standards were available, we have synthesized characterized both 3β‐FBT its 3α isomer use standards. The two compounds...
N ‐Methyl‐3‐phenyl‐norbornan‐2‐amine ( ‐methyl‐3‐phenylbicyclo[2.2.1]heptan‐2‐amine, Camfetamine ™ ) is available from a number of online legal highs/research chemicals' vendors. Although it was developed as an analeptic by Merck in the early 1960s, never commercialized. However, Association Independent Research Chemical Retailers (AIRCR), umbrella organization for vendors, has redeveloped use recreational drug. closely related to fencamfamine which been widely used central nervous system...
Objectives To identify risk factors that contribute to outbreaks of COVID-19 in the workplace and quantify their effect on outbreak risk. Methods We identified cases investigated characteristics individuals, workplaces, areas they work mode commute work, through data linkages based Middle Layer Super Output Areas England between 20 June 2021 February 2022. estimated population-level associations potential outbreaks, adjusting for plausible confounders using a directed acyclic graph. Results...
Abstract Cathinones are often sold as “legal” alternatives to controlled stimulants such amphetamine, MDMA and cocaine. the second largest group of new psychoactive substances (NPS), with close 170 monitored by European Monitoring Centre for Drugs Drug Addiction (EMCDDA). Although all cathinones related parent compound cathinone, one principles in khat, assigning consistent, informative user‐friendly common names these is challenging. Over time different naming approaches have been applied,...
Abstract Background Norovirus is a leading cause of acute gastroenteritis, adding to strain on healthcare systems. Diagnostic test reporting norovirus often delayed, resulting in incomplete data for real-time surveillance. Methods To nowcast the case burden generalised additive model, semi-mechanistic Bayesian joint process and delay structural time series model including syndromic surveillance were developed. These models evaluated over weekly nowcasts using probabilistic scoring framework....
Accurate and representative surveillance is essential for understanding the impact of influenza on healthcare systems. During 2022–2023 season, Northern Hemisphere experienced its most significant epidemic wave since onset COVID-19 pandemic in 2020. Concurrently, new systems, developed response to pandemic, became available within health services. In this study, we analysed per capita admission rates from National Health Service hospital Trusts across four systems England during winter...