A5037111724- Acupuncture Treatment Research Studies
- Healthcare and Venom Research
- Traditional Chinese Medicine Studies
- Cancer Immunotherapy and Biomarkers
- Inflammasome and immune disorders
- interferon and immune responses
- Cancer-related Molecular Pathways
- Microtubule and mitosis dynamics
- HER2/EGFR in Cancer Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Thyroid Cancer Diagnosis and Treatment
- Monoclonal and Polyclonal Antibodies Research
- Cancer, Stress, Anesthesia, and Immune Response
Harbin Medical University
2023-2024
Fudan University Shanghai Cancer Center
2024
Shanghai Medical College of Fudan University
2024
Third Affiliated Hospital of Harbin Medical University
2023-2024
Abstract Programmed death receptor-1 (PD-1) inhibitors are ineffective against microsatellite-stable (MSS) colorectal cancer. Electroacupuncture (EA) has oncosuppressive and immunomodulatory properties. Here, we investigated the antitumor effects of EA explored feasibility combined with anti–PD-1 in MSS Results showed that exerted its effect an intensity-specific manner, moderate-intensity (1.0 mA) induced maximal tumor inhibition. enhanced immune responses by increasing lymphocytes granzyme...
Background and Aims: HCC, particularly the multifocal features aggressive invasion dismal prognosis. Locoregional treatments were often refractory to eliminate tumor tissue, resulting in residual cells persisting subsequent progression. Owing problematic delivery systemic therapies, such as lenvatinib (LEN) therapy, show limited clinical benefit preventing Therefore, more advanced strategies for postablative HCC are urgently needed. Approach Results: Motivated by chemotaxis penetration of...
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<div>Abstract<p>Programmed death receptor-1 (PD-1) inhibitors are ineffective against microsatellite-stable (MSS) colorectal cancer. Electroacupuncture (EA) has oncosuppressive and immunomodulatory properties. Here, we investigated the antitumor effects of EA explored feasibility combined with anti–PD-1 in MSS Results showed that exerted its effect an intensity-specific manner, moderate-intensity (1.0 mA) induced maximal tumor inhibition. enhanced immune responses by increasing...
<p>Supplementary Figure S6 and legend</p>
<p>Supplementary Figure S4 and legend</p>
<p>Supplementary Figure S3 and legend</p>
<div>Abstract<p>Programmed death receptor-1 (PD-1) inhibitors are ineffective against microsatellite-stable (MSS) colorectal cancer. Electroacupuncture (EA) has oncosuppressive and immunomodulatory properties. Here, we investigated the antitumor effects of EA explored feasibility combined with anti–PD-1 in MSS Results showed that exerted its effect an intensity-specific manner, moderate-intensity (1.0 mA) induced maximal tumor inhibition. enhanced immune responses by increasing...
<p>Supplementary Figure S3 and legend</p>
<p>Supplementary Figure S4 and legend</p>
<p>Supplementary Figure S2 and legend</p>
<p>Supplementary Figure S6 and legend</p>
Anaplastic thyroid cancer (ATC) is the most lethal tumor arising from follicular epithelium. Lenvatinib an off-label use option for ATC patients in many countries but approved prescription Japan. However, lenvatinib resistance a substantial clinical challenge. Clinical samples including lenvatinib-resistant tumors are used to build patient-derived cells and xenografts. High-throughput drug screening synergy analyses performed identify effective combination partner lenvatinib. Cellular...