A5067546803- Healthcare and Venom Research
- Acupuncture Treatment Research Studies
- Traditional Chinese Medicine Studies
- Inflammasome and immune disorders
- Cancer Immunotherapy and Biomarkers
- interferon and immune responses
- Advanced Breast Cancer Therapies
- HER2/EGFR in Cancer Research
- Fatty Acid Research and Health
- Iron Metabolism and Disorders
- Diet and metabolism studies
- Pharmacology and Obesity Treatment
- Metabolism and Genetic Disorders
- Folate and B Vitamins Research
- Cancer, Stress, Anesthesia, and Immune Response
- Chronic Lymphocytic Leukemia Research
- Pharmacological Effects of Natural Compounds
- Pancreatic function and diabetes
- Liver Disease Diagnosis and Treatment
- Hippo pathway signaling and YAP/TAZ
- Cancer Treatment and Pharmacology
Harbin Medical University
2023-2024
First Affiliated Hospital of Harbin Medical University
2023-2024
Pfizer (United States)
2024
Heilongjiang University of Chinese Medicine
2023
Abstract Programmed death receptor-1 (PD-1) inhibitors are ineffective against microsatellite-stable (MSS) colorectal cancer. Electroacupuncture (EA) has oncosuppressive and immunomodulatory properties. Here, we investigated the antitumor effects of EA explored feasibility combined with anti–PD-1 in MSS Results showed that exerted its effect an intensity-specific manner, moderate-intensity (1.0 mA) induced maximal tumor inhibition. enhanced immune responses by increasing lymphocytes granzyme...
PF-07220060 is a novel potent oral CDK4i with significant sparing of CDK6. Preliminary safety and dose escalation data from this phI/IIastudy were previously presented. Here we report updated efficacy in pts HR+/HER2− mBC, who progressed on prior CDK4/6i ET, treated + ET. This study advanced solid tumors was enriched for mBC received ≥2 lines treatment including ET CDK4/6i. Prior fulvestrant chemotherapy allowed. Study objectives to assess safety, tolerability, antitumor activity alone...
<p>Supplementary Figure S2 and legend</p>
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<p>Supplementary Figure S5 and legend</p>
<p>Supplementary Figure S1 and legend</p>
<div>Abstract<p>Programmed death receptor-1 (PD-1) inhibitors are ineffective against microsatellite-stable (MSS) colorectal cancer. Electroacupuncture (EA) has oncosuppressive and immunomodulatory properties. Here, we investigated the antitumor effects of EA explored feasibility combined with anti–PD-1 in MSS Results showed that exerted its effect an intensity-specific manner, moderate-intensity (1.0 mA) induced maximal tumor inhibition. enhanced immune responses by increasing...
<p>Supplementary Figure S6 and legend</p>
<p>Supplementary Figure S4 and legend</p>
<p>Supplementary Figure S3 and legend</p>
<div>Abstract<p>Programmed death receptor-1 (PD-1) inhibitors are ineffective against microsatellite-stable (MSS) colorectal cancer. Electroacupuncture (EA) has oncosuppressive and immunomodulatory properties. Here, we investigated the antitumor effects of EA explored feasibility combined with anti–PD-1 in MSS Results showed that exerted its effect an intensity-specific manner, moderate-intensity (1.0 mA) induced maximal tumor inhibition. enhanced immune responses by increasing...
<p>Supplementary Figure S3 and legend</p>
<p>Supplementary Figure S4 and legend</p>
<p>Supplementary Figure S2 and legend</p>
<p>Supplementary Figure S6 and legend</p>
<title>Abstract</title> Background: Evidence regarding the health effects of saturated fatty acids (SFAs), monounsaturated (MUFAs), and total polyunsaturated (PUFAs) is controversial. Our objective was to explore associations between serum-free mortality among cancer survivors. Methods: The study included 6,575 participants with or without diagnosis aged 20 years older a who were recruited before December 2014 followed up through 31, 2019. Hazard ratios (HRs) 95% confidence intervals (CIs)...