A5102953899- Computational Drug Discovery Methods
- Bioinformatics and Genomic Networks
- Machine Learning in Bioinformatics
- Tryptophan and brain disorders
Chongqing University of Posts and Telecommunications
2024-2025
Lung cancer remains a leading cause of cancer-related mortality, primarily because the lack effective diagnostic and therapeutic biomarkers. To address issue fragmented biomarker data across numerous publications, we have developed Cancer Biomarker Database (LCBD, http://lcbd.biomarkerdb.com ). We comprehensively reviewed biomarker-related studies up to June 30, 2023, extracted relevant information. The identified biomarkers were systematically annotated, including genes, proteins, GO terms,...
Abstract Computational drug repositioning, which involves identifying new indications for existing drugs, is an increasingly attractive research area due to its advantages in reducing both overall cost and development time. As a result, growing number of computational repositioning methods have emerged. Heterogeneous network-based been shown outperform other approaches. However, there dearth systematic evaluation studies these methods, encompassing performance, scalability usability, as well...