A5079527868- Autophagy in Disease and Therapy
- Advanced Chemical Sensor Technologies
- Spectroscopy and Chemometric Analyses
- Adipose Tissue and Metabolism
- Adipokines, Inflammation, and Metabolic Diseases
Seoul National University
2024
Abstract Adipose tissue (AT) adapts to overnutrition in a complex process, wherein specialized immune cells remove and replace dysfunctional stressed adipocytes with new fat cells. Among recruited AT, lipid-associated macrophages (LAMs) have emerged as key players obesity diseases involving lipid stress inflammation. Here, we show that LAMs selectively express transmembrane 4 L six family member 19 (TM4SF19), lysosomal protein represses acidification through its interaction Vacuolar-ATPase....
A convolutional neural network (CNN) architecture is developed to improve the pulse shape discrimination (PSD) power of gadolinium-loaded organic liquid scintillation detector reduce fast neutron background in inverse beta decay candidate events NEOS-II data. spectrum an event constructed using a Fourier transform time domain raw waveforms and put into CNN. An early data set evaluated by CNN after it trained low energy $β$ $α$ events. The signal-to-background ratio averaged over 1-10 MeV...