The six-minute walk test (6MWT) is a key tool for assessing fitness in obese individuals, but existing reference equations the distance (6MWD) are limited and overlook work (6MWW), turn limiting clinical applicability of test. This study aims to establish new 6MWD 6MWW improve our understanding functional capacity Chinese adults. A cross-sectional was conducted at Wenzhou People's Hospital from July 2021 June 2023. Obese adults (BMI > 30 kg/m²), aged 18–69 years, completed 6MWT following...

Abstract High plasma levels of homocysteine (Hcy) are regarded as a risk factor for atrial fibrillation (AF), which is closely associated with the pathological consequence fibrosis and can lead to heart failure high mortality rate; here, we show that mediated by relationship between canonical transient receptor potential 3 (TRPC3) channels sirtuin type 1 (SIRT1) under stimulation Hcy. The left appendage was obtained from patients either sinus rhythm (SR) or AF used evaluate concentration Hcy...

In this paper, we explore the physical-layer security in a wireless network consisting of multiple user pairs face eavesdroppers, which are deployed by an adversary for tapping confidential transmissions deliberately. We propose friendly jammer-assisted user-pair selection (FJaUPS) scheme to improve security-reliability tradeoff (SRT). Conventionally, jammer is used transmit artificial noise that specially designed onto null space main channel (spanning from source legitimate destination)...

In this paper, the artificial-noise (AN)-aided downlink distributed antenna system with simultaneous wireless information and power transfer is considered, in which legitimate user uses power-splitting (PS) scheme to simultaneously decode harvest energy. To prevent eavesdroppers from wiretapping user, AN transmitted confidential signal at transmitter. The secrecy energy efficiency maximization (SEEM) problem studied under constraints of minimum rate requirement, required harvested energy,...

Previous studies have confirmed the clinical efficacy of sacubitril/valsartan (Sac/Val) for treatment heart failure with reduced ejection fraction (HFrEF). However, role Sac/Val in preserved (HFpEF) remains unclear. is a combination therapeutic medicine comprising sacubitril and valsartan that acts as first angiotensin receptor blocker neprilysin inhibitor (angiotensin-receptor (ARNI)). Here, we investigated high-salt diet-induced HFpEF coupled vascular injury well underlying mechanism. Rats...

The six-minute walk test (6MWT) is a safe, simple, inexpensive tool for evaluating the functional exercise capacity. However, there lack of standard reference equations distance (6MWD) in healthy Chinese Han population with an age 18–30 years. aims present study were as follows: 1) to measure anthropometric data and walking sample population, aged years; 2) construct 6MWD; 3) compare measured 6MWD our cohort previously published equations. data, demographic, lung function years,...

Silica dust particles are representative of air pollution and long-term inhalation silicon-containing through the respiratory tract can cause pulmonary fibrosis. Epithelial-mesenchymal transformation (EMT) plays an important role in development This process relax cell-cell adhesion complexes enhance cell migration invasion properties these cells. Dysregulation microRNA-34c (miR-34c) is highly correlated with organ fibrosis including In this study, we found that miR-34c-5p could alleviate...

Abstract Background The six-minute walking test (6MWT) is a tool that plays key role in evaluating the functional exercise capacity, prognosis and evaluation of treatment response patients with various cardiopulmonary diseases. However, standard reference equations are currently unavailable for distance (6MWD) people aged 60–85 years China. purpose this study was to 1) measure 6MWD healthy Chinese years, 2) establish predicting 6MWD, 3) compare our reported previously published studies....

Objective to evaluate the clinical efficacy and safety of sacubitril valsartan in treatment heart failure (HF) with midrange ejection fraction after acute myocardial infarction (AMI) diabetic patients. From January 2015 July 2020, HF patients diabetes mellitus complicated AMI were retrospectively analyzed. According medication, they divided into 2 groups, that is, group (84 cases) (86 cases). Valsartan took capsule (80 mg/capsule, Beijing Novartis Pharmaceutical Co., Ltd) 80 mg, qd, on basis...

Although the six-minute walk test (6MWT) is widely used as a measure of exercise capacity, it may not be applicable in some settings and populations. This issue has led to increased use two-minute (2MWT) assess capacity. The main objective this study establish reference equations for distance (2MWD) healthy Chinese adults aged 18-85 years.A total 973 volunteers took part study. We obtained verbal consent from all participants before test, design was approved by ethics committees Wenzhou...

Acquired long QT syndrome caused by hypopituitarism and transient ST-segment elevation has not been reported in cardiac arrest patients. We report a case of extremely dangerous acquired elevation. A 44-year-old Chinese woman with renal failure experienced sudden the haemodialysis room. Subsequent electrocardiogram showed prolongation This patient's medical history, subsequent laboratory results pituitary magnetic resonance imaging suggested hypopituitarism. Transient on was considered to be...

To investigate whether postoperative anion gap (AG) is associated with short- and long-term mortality in patients following cardiac surgery.We conducted a retrospective cohort study of adults who underwent surgery from the Medical Information Mart for Intensive Care - III database. The generalized additive model (GAM), logistic regression, Cox regression were performed to assess correlations between AG levels in-hospital, 90-day, 4-year mortality. Linear was used evaluate associations length...

This paper investigates secrecy energy efficiency (SEE) optimization problem for simultaneous wireless information and power transfer (SWIPT) in a multiple-input single-output (MISO) downlink system, which the legitimate user (LU) exploits splitting (PS) scheme decoding (ID) harvesting (EH) simultaneously. In order to prevent eavesdroppers from disturbing reception of user, BS also emits artificial noise (AN). The objective is maximize SEE by jointly optimizing confidential signal power, AN...

Studies have shown that the reference equations for six-minute walking distance (6MWD), which were mainly derived from healthy, normal-weight people, are not suitable individuals with obesity. The main purpose of this study was to establish 6MWD in obese Chinese subjects.In our study, a total 214 obesity performed tests (6MWTs) according American thoracic society (ATS) guidelines, and longer used further analysis. developed using stepwise multiple regression newly established compared...

Location-based services have become an important part of the daily life. Fingerprint localization has been put forward to overcome shortcomings traditional positioning algorithms in indoor scenario and rich scattering environment. In this paper, a single-site multiple-input multiple-output (MIMO) orthogonal frequency division multiplexing (OFDM) system is modeled, from which angle delay channel power matrix (ADCPM) extracted. Considering changing environment, auto encoders are used generate...

Background and objective While the six-minute walk test (6MWT) is often used to assess exercise capacity, less well-known two-minute (2MWT) more feasible for some patients. In previous studies, we developed reference equations distance (2MWD) healthy Chinese adults. However, our study did not recruit people with obesity, apply participants a body mass index (BMI) > 30 kg/m 2 . The main of this was establish 2MWD among middle-aged elderly individuals obesity. Methods A total 295 were...

Hereditary hemorrhagic telangiectasia is a rare autosomal dominant disorder characterized by abnormal blood vessel formation. When an vascular architecture affects the lungs and central nervous system, serious complications can occur. We report missed case of hereditary with pulmonary arteriovenous malformations cerebral malformations. A 22-year-old Chinese female was taken to emergency room because unconsciousness. Emergency head contrast-enhanced computed tomography transthoracic contrast...

In this study, the authors explore a wireless network consisting of multiple smart terminals relying on multi‐mode in presence an eavesdropper, where eavesdropper may be deployed to wiretap communications deliberately. general, terminal can switched between licensed modes (e.g. LTE) and unlicensed WiFi) according user's demands costs). The designed tradeoff is that met by switching, but security transmissions deteriorated, as overheard eavesdropper. propose transmission mode aware scheduling...