A5031924045- Vestibular and auditory disorders
- MicroRNA in disease regulation
- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- SARS-CoV-2 and COVID-19 Research
- Viral Infections and Outbreaks Research
- Intracerebral and Subarachnoid Hemorrhage Research
- Glaucoma and retinal disorders
- Cerebrospinal fluid and hydrocephalus
- Neurosurgical Procedures and Complications
- Cardiac Structural Anomalies and Repair
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebral Venous Sinus Thrombosis
- Healthcare Systems and Public Health
- Neurological Disease Mechanisms and Treatments
- Mechanical Circulatory Support Devices
- Sleep and related disorders
- Medical Research and Treatments
- Psychosocial Factors Impacting Youth
- COVID-19 Clinical Research Studies
- Air Quality and Health Impacts
- Acupuncture Treatment Research Studies
- Hydrogen's biological and therapeutic effects
- Cardiovascular Health and Risk Factors
- Long-Term Effects of COVID-19
Beijing Luhe Hospital Affiliated to Capital Medical University
2022-2025
North China University of Science and Technology
2020-2023
Guangzhou Medical University
2021-2022
Guangzhou Eighth People's Hospital
2020-2022
Chinese Academy of Medical Sciences & Peking Union Medical College
2021
Second Affiliated Hospital of Nanchang University
2021
Nanchang University
2021
Suzhou Institute of Systems Medicine
2021
Capital Medical University
2017-2018
Beijing Chaoyang Emergency Medical Center
2018
The widespread prevalence of coronavirus disease-2019 (COVID-19) which is caused by severe respiratory syndrome 2 (SARS-CoV-2) infection, has resulted in a global public health emergency. However, there are no sensitive biomarkers to predict the disease prognosis COVID-19 patients. Here, we have identified interleukin-8 (IL-8) as biomarker candidate different severity and While serum IL-6 become obviously elevated patients, IL-8 was easily detectible patients with mild syndromes....
Abstract Since the outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome 2 (SARS-CoV-2), public health worldwide has been greatly threatened. The development an effective treatment for this infection is crucial and urgent but hampered incomplete understanding viral mechanism lack specific antiviral agents. We previously reported that teicoplanin, a glycopeptide antibiotic commonly used in clinic to treat bacterial infection, significantly restrained cell...
Objective Vestibular and psychiatric disorders are very closely related. Previous research shows that the discomfort dysfunction caused by dizziness in patients can affect psychological processes, leading to anxiety depression, irritation of depression aggravate dizziness. But causal relationship between recovery period stroke Post-stroke (PSD) / (PSA) is not clear. Identifying them enable us conduct more targeted treatments.
China has the largest elderly population globally; growth rate of aged tendency was higher than that Western countries. Given distinctions in historical, ethnic, and economic status as well socio-cultural background, Chinese adults had different sleep patterns compared with other Considering heavy disease burden caused by activities daily living (ADL) disability, we conducted a cross-sectional analysis using data from Health Retirement Longitudinal Study (CHARLS) to test hypothesis...
Abstract Objectives: Follow-up observation of changes in intracranial plaques and lenticulostriate arteries (LSAs) under the standard medical treatment can help further observe effects. This study aims to symptomatic atherosclerosis LSAs conventional using high-resolution magnetic resonance imaging (HR-MRI). Subjects Methods: Thirty-eight middle cerebral artery stenotic patients were consecutively enrolled from October 2016 July 2018 HR-MRI was performed within two weeks onset acute ischemic...
Objectives Recent studies reported that 24-hour ambulatory blood pressure variability (ABPV) was associated with lacunar infarction and white matter hyperintensities (WMH). However, the relationship between ABPV enlarged perivascular spaces (EPVS) has not been investigated. Thus, our study aimed to investigate whether is EPVS by monitoring (ABPM). Design We conducted this as a cross-sectional study. Settings The based on patients who presented for physical examinations in hospital from May...
Since the outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome 2 (SARS-CoV-2), public health worldwide has been greatly threatened. The development an effective treatment for this infection is crucial and urgent but hampered incomplete understanding viral mechanisms lack specific antiviral agents. We previously reported that teicoplanin, a glycopeptide antibiotic commonly used in clinic to treat bacterial infection, significantly restrained cell entry...
Lacunae, brain atrophy, white matter hyperintensity, enlarged perivascular space and microbleed are magnetic resonance imaging (MRI) markers of cerebral small-vessel disease (cSVD). Studies have reported that higher blood pressure variability (BPV) predicted cardiovascular risk in hypertensive patients; however, the association between BPV total MRI burden cSVD has not been investigated. In this study, we aimed to explore relationship burden.We prospectively recruited patients who attended...
Previous studies have confirmed the clinical efficacy of sacubitril/valsartan (Sac/Val) for treatment heart failure with reduced ejection fraction (HFrEF). However, role Sac/Val in preserved (HFpEF) remains unclear. is a combination therapeutic medicine comprising sacubitril and valsartan that acts as first angiotensin receptor blocker neprilysin inhibitor (angiotensin-receptor (ARNI)). Here, we investigated high-salt diet-induced HFpEF coupled vascular injury well underlying mechanism. Rats...
Backgrounds: Enlarged perivascular spaces (EPVS) have been identified as a marker of cerebral small vessel diseases (CSVD). Ambulatory blood pressure (ABP) is the strongest predictor hypertension-related brain damage. However, relationship between ABP levels and EPVS unclear.Objectives: This study aimed to investigate association by 24-hour ambulatory monitoring (ABPM).Methods: We prospectively recruited inpatients for physical examinations in our hospital from May 2013 Jun 2016. ABPM data...
Whether there are differences in pathogenesis among different types and subtypes of cerebral watershed infarction (WSI) is controversial since they have been combined into a single group most previous studies. We prospectively identified 340 supratentorial WSI patients at Beijing Chao-Yang Hospital, Capital Medical University, China classified them based on diffusion-weighted imaging(DWI) templates. Baseline characteristics, clinical courses neuroradiological features were compared with WSI....
Abstract Silent cerebrovascular diseases, including silent brain infarcts (SBI), white matter hyperintensity (WMH), and cerebral microbleed, are closely correlated with stroke progression. The purpose of this study was to investigate the prevalence potential risk factors SBI WMH in young patients first-ever stroke. A total 400 were included received magnetic resonance imaging test. distributions subtypes analyzed based on patients’ age gender. evaluated different groups subtypes. Independent...
<b><i>Background:</i></b> Although increasing evidence has demonstrated that elevated homocysteine (Hcy) levels may be an important contributor for the development of cerebral infarction, rare studies focused on its diagnostic and early prognostic roles in acute lacunar infarction. <b><i>Methods:</i></b> A total 197 patients with infarction 192 to form control group were prospectively recruited between January 2013 February 2017. Early...
This study aimed to investigate the therapeutic effects of candesartan combined with music therapy on diabetic retinopathy depression and assess molecular mechanisms. Associated animal model diabetes mellitus was established in rats. Pathological changes hippocampus were detected by haematoxylin eosin (H&E) staining. Terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) used detect retinal cell apoptosis. Angiotensin II (Ang II) peripheral blood neurotransmitters,...
The antisaccades (AS) task is considered a reliable indicator of inhibitory control eye movements in humans. Achieving good AS performance requires efficient cognitive processes that are sensitive to changes brain structure. White matter hyperintensities (WMH) can cause subcortical-cortical dysconnectivity, affecting diverse domains. Thus, the was investigated patients with WMH cerebral small vessel disease (CSVD).
Objectives: Patients with vestibular migraine (VM) show a significant decrease in gray matter cortical regions associated pain and processing, as revealed by head functional magnetic resonance imaging. We predict that these changes can be reflected intentional saccadic eye movements. This study aims to establish whether there are abnormalities movements patients VM. Subjects Methods: is retrospective involving two groups of patients, including 39 the VM group 38 control group. The matched...
<title>Abstract</title> <bold>Objectives</bold> Vestibular neuritis (VN) etiology remains elusive, with hypotheses suggesting viral infection, non-infectious inflammation, or immune responses. This study aims to assess the T and B lymphocyte subsets cytokine expressions in blood of vestibular patients. shed light on its pathogenesis provided valuable hematological markers for clinical prognosis.<bold>Methods</bold> A retrospective analysis was conducted 25 subjects diagnosed acute at...
Objective: To investigate the effect of oxidative stress caused by heat exposure on blood pressure increase treadmill rats and intervention antioxidants. Methods: In June 2021, Twenty-four healthy SD male were randomly divided into four groups: normal temperature feeding, treadmill, high supplementation with vitamin C groups, 6 in each group. The run platform or environment for 30 min morning afternoon daily, days per week. daily supplement dose group was 10 mg/kg. BP recordings done at end...
A successful and useful treatment for end-stage heart failure is Left ventricular assist device (LVAD). An important part - a hydrodynamically suspended impeller exposed to corrosive conditions, required sealed hermetically into micro packages. Laser beam welded (LBW) Ti6Al4V alloy has been adopted in anti-corrosion packages the of Thin narrow welds were such medical equipment. Pulsed Nd:YAG welding was successfully as sealing method impeller.