A5081573625- Viral Infections and Vectors
- Hepatitis B Virus Studies
- Animal Disease Management and Epidemiology
- Virology and Viral Diseases
- Viral Infections and Outbreaks Research
- Zoonotic diseases and public health
- Viral gastroenteritis research and epidemiology
Bernhard Nocht Institute for Tropical Medicine
2022-2023
German Center for Infection Research
2022
Ebolaviruses cause outbreaks of haemorrhagic fever in Central and West Africa. Some members this genus such as Ebola virus (EBOV) are highly pathogenic, with case fatality rates up to 90%, whereas others Reston (RESTV) apathogenic for humans. Bombali (BOMV) is a novel ebolavirus which complete genome sequences were recently found free-tailed bats, although no infectious could be isolated. Its pathogenic potential humans unknown. To address question, we first determined whether proteins...
Nipah virus (NiV) is an emerging zoonotic paramyxovirus that causes severe disease in humans and livestock. Due to its high pathogenicity the lack of available vaccines therapeutics, NiV needs be handled biosafety level 4 (BSL-4) laboratories. Safe inactivation samples containing thus necessary allow further processing lower containment areas. To date, there only limited information on methods validated by BSL-4 facilities can used as a reference. Here, we compare some most common order...