A5080606702- Nanoplatforms for cancer theranostics
- Photoacoustic and Ultrasonic Imaging
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Respiratory viral infections research
- Thermography and Photoacoustic Techniques
- Extracellular vesicles in disease
- Transition Metal Oxide Nanomaterials
- Perovskite Materials and Applications
- Energy Load and Power Forecasting
- Smart Grid and Power Systems
- Water Quality Monitoring Technologies
- Air Quality Monitoring and Forecasting
- Hydrological Forecasting Using AI
- interferon and immune responses
- Photodynamic Therapy Research Studies
- Long-Term Effects of COVID-19
- Optical Imaging and Spectroscopy Techniques
- Computational Physics and Python Applications
- Immune responses and vaccinations
- Respiratory Support and Mechanisms
- Advanced Memory and Neural Computing
- Neonatal Respiratory Health Research
University of Hong Kong
2023-2024
Beijing University of Posts and Telecommunications
2024
Hong Kong Science and Technology Parks Corporation
2024
Shanghai Jiao Tong University
2019-2023
Beihang University
2023
Intranasal infection of newly-weaned Syrian hamsters by SARS-CoV-2 Omicron variants can lead to brain inflammation and neuron degeneration with detectable low level viral load sparse expression nucleoprotein.
We demonstrate high contrast optical-resolution photoacoustic microscopy (OR-PAM) imaging by using biocompatible, indirect band gap silicon nanoparticles (SiNPs) as agents. The SiNPs were synthesized high-energy ball milling of crystalline wafers, followed hydrosilylation with bifunctional olefinic ligands to enable water solubility and bioconjugation. When uniformly dispersed in water, the an average particle size about 114 nm showed remarkably extinction coefficients, more than 2 × 1010...
Photoacoustic microscopy (PAM) is a promising imaging modality because it able to reveal optical absorption contrast in high resolution on the order of micrometer. It can be applied an endoscopic approach by implementing PAM into miniature probe, termed photoacoustic endoscopy (PAE). Here we develop focus-adjustable PAE (FA-PAE) probe characterized both (in micrometers) and large depth focus (DOF) via novel optomechanical design for adjustment. To realize DOF 2-mm plano-convex lens specially...
In this study, a novel photoacoustic microscopy (PAM) probe integrating white-light (WLM) modality that provides guidance for PAM imaging and complementary information is implemented. One single core of an fiber bundle employed to deliver pulsed laser excitation mode, which high resolution with deep penetration. Meanwhile, WLM the used transmit two-dimensional superficial images. Lateral 7.2 μm achieved. Since miniature components are used, diameter only 1.7 mm. Imaging phantom animals in...
Abstract Long COVID or Post-acute sequalae of COVID-19 (PASC) defines the persistent signs, symptoms, and conditions long after initial SARS-CoV-2 infection which affecting over 10% patients, with 40% them respiratory system. The lung histopathological changes underlying mechanism remain elusive. Here we systemically investigate transcriptional at 7, 14, 42, 84 120 days-post-SARS-CoV-2-infection (dpi) in hamster. We demonstrate viral residues, chronic inflammatory fibrotic from 42dpi to...
Photoacoustic microscopy (PAM) is a promising imaging modality because it able to reveal optical absorption contrast in high resolution on the order of micrometer. It can be applied an endoscopic approach by implementing PAM into miniature probe, termed as photoacoustic endoscopy (PAE). Here we develop focus-adjustable PAE (FA-PAE) probe characterized both (in micrometers) and large depth focus (DOF) via novel optomechanical design for adjustment. To realize DOF 2-mm plano-convex lens...
A miniature endoscope capable of imaging multiple tissue contrasts in high resolution is highly attractive, because it can provide complementary and detailed information internal organs. Here we present a photoacoustic (PA)-fluorescence (FL) for optical-resolution PA microscopy (PAM) FL (FLM). The with diameter 2.8 mm achieves lateral resolutions 5.5 6.3 µm PAM FLM modes, respectively. In vivo zebrafish larvae mouse ear conducted, high-quality images are obtained. Additionally, endoscopic...
Abstract CsPbI 3 is considered to one potential material in the future resistive random access memory(RRAM). There are four crystal types of , among which δ phase most stable and available commercialize. However, inherent defect -CsPbI results its inferior switching performance other types. Here, we present a new structure solve this problem. Carbon nanotube (CNT) was inserted into two interfaces Ag/ /ITO /FTO adjust resistance performance. It found that introduction carbon layer can...