A5071085117- Education and Public Policy
- Child Welfare and Adoption
- HER2/EGFR in Cancer Research
- Monoclonal and Polyclonal Antibodies Research
- Latin American socio-political dynamics
- Genetic Associations and Epidemiology
- Children's Physical and Motor Development
- Quinazolinone synthesis and applications
- Public Health and Social Inequalities
- Linguistic Studies and Language Acquisition
- Microplastics and Plastic Pollution
- Healthcare and Environmental Waste Management
- Autism Spectrum Disorder Research
- Genetics and Neurodevelopmental Disorders
- Galectins and Cancer Biology
- Psychology and Mental Health
- Physical Education and Gymnastics
- Physical Education and Pedagogy
- Bipolar Disorder and Treatment
- Evasion and Academic Success Factors
- Migration, Racism, and Human Rights
- Urban and sociocultural dynamics
- Child and Adolescent Psychosocial and Emotional Development
- Schizophrenia research and treatment
- Education and Digital Technologies
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
2025
Universidade do Porto
2025
Universidade Lusófona
2023
Faculdade Brasil
2023
Karumbé
2015
Popular University of Cesar
2014
Centro de Estudos e Sistemas Avançados do Recife
2014
Agency for Science, Technology and Research
2013
Bioinformatics Institute
2013
University of Minho
2010
Abstract Helicobacter pylori chronic infection is the highest risk factor for development of gastric cancer, being this Gram‐negative bacterium classified as carcinogenic. The mounting resistance H. to antibiotics calls innovative therapeutic strategies. Here, proof‐of‐concept studies that support a “trojan horse” strategy based on cholesterol‐grafted nanoparticles (Chol‐NP) counteract are depicted. ability specifically recognize and bind surface grafted cholesterol demonstrated by its...
Abstract The long‐standing concept that schizophrenia (SC) and bipolar disorder (BP) represent two distinct illnesses has been recently challenged by findings of overlap genetic susceptibility loci for these diseases. We report here the results a linkage disequilibrium (LD) analysis chromosome 18 utilizing subjects with SC from Central Valley Costa Rica. Evidence association ( P < 0.05) was obtained in three chromosomal regions: 18p11.31 (D18S63), 18q12.3 (D18S474), 18q22.3‐qter...
Synthetic plastics have become an indispensable component of modern life, and the amount disposal has increased dramatically as a result.With human population increasing, it is expected that prevalence plastic debris in environment will also increase, unless sustainable daily habits are incorporated, waste management improved, new alternative materials discovered popularized.To date, several reports show negative effects on marine freshwater fauna (e.g.invertebrates, birds, turtles, mammals).
Objective: This study used the population of Central Valley Costa Rica (CVCR) and phenotyping strategies alternative to DSMIV classifications investigate association neuregulin 1 with schizophrenia. Method: Using 134 family trios a history psychosis, we genotyped six seven markers originally identified be associated schizophrenia in Iceland. Results: The Icelandic haplotype was not CVCR population. However, novel found overrepresented subjects functional psychosis (global P ‐value >...
Linkage studies using multiplex families have repeatedly implicated chromosome 8 as involved in schizophrenia etiology. The reported areas of linkage, however, span a wide chromosomal region. present study used the founder population Central Valley Costa Rica and phenotyping strategies alternative to DSM-IV classifications attempts further delimitate on that may harbor susceptibility genes. A linkage disequilibrium screen was performed family trios individuals with history psychosis. Four...
O presente estudo exploratório examinou o desenvolvimento mental e a qualidade do funcionamento sócio-emocional de 16 crianças entre os 3 6 anos, institucionalizadas em Centros Acolhimento Temporário, relacionando-os com das narrativas sobre apego suas cuidadoras. Foram utilizadas Escala Desenvolvimento Mental Griffiths, Questionário Comportamentos, as Narrativas Apego Attachment Q-Sort. Os resultados revelaram que nível foi inferior aos valores normativos. Além disso, apresentados ao da...
The pressure exerted by drugs targeted to a protein in any therapy inevitably leads the emergence of drug resistance. One major mechanism resistance involves mutation key residues target protein. Drugs that competitively replace natural substrate are often made ineffective mutations reduce drug's affinity relative substrate. Hence atomic level understanding mechanisms underlie this behavior is utmost importance efforts design new can such mutant proteins. Methods predict these before they...
La esquizofrenia es una enfermedad que afecta aproximadamente al 1% de la población mundial. Es las enfermedades psiquiátricas más debilitantes con un alto costo económico, social, familiar y personal. En Costa Rica, constituye primera causa internamiento entre los desórdenes psiquiátricos en el Hospital Nacional Psiquiátrico. El presente estudio analiza diagnóstico preliminar primeros 120 pacientes incluidos proyecto sobre Genética Esquizofrenia. Al comparar del entrevistador, final por...
O Governo Brasileiro vem criando programas que incentivam a continuidade da capacitação profssional. programa Rede e-Tec, possui missão de dispor cursos técnicos na modalidade educação distância para as localidades isoladas dos grandes centros. Este trabalho foi construído com fnalidade compreender o perfl estudantes ingressos nestes cursos, analisando visão do aluno quanto estrutura didática disponível e expectativas ao fnal curso. Com base nos resultados pesquisa, acredita-se está...
Objetivo: A diferenciação entre AVE isquêmico e hemorrágico é essencial para estabelecer um curso de tratamento adequado prognóstico. O presente artigo tem como objetivo elucidar comparar diferentes dados sobre o uso da tomografia computadorizada crânio no diagnóstico acidente vascular encefálico. Metodologia: No estudo, foi realizada pesquisa cunho qualitativo, com elaboração revisão literatura do tipo narrativa, tendo meios fundamentação teórica os artigos científicos disponíveis on-line...
ResumoOs seres humanos sempre enfrentaram vários obstáculos ao longo de várias gerações, todavia nestes últimos quatro anos viram-se frente a com pandemia COVID-19 e respetivos confinamentos, hipótese uma terceira Guerra Mundial, mudanças climáticas, desastres naturais, subida da inflação muitas outras dificuldades.Este estudo tem como objetivo avaliar perceção inteligência emocional (IE), resiliência (Rs) stress ocupacional (SO) nos/as interventores/as sociais exercer em Portugal...