- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Antimicrobial Resistance in Staphylococcus
- Vehicle Routing Optimization Methods
- Drug Transport and Resistance Mechanisms
- Antibiotics Pharmacokinetics and Efficacy
- Advanced Algorithms and Applications
- Service-Oriented Architecture and Web Services
- Blind Source Separation Techniques
- Bacterial Identification and Susceptibility Testing
- Advanced Manufacturing and Logistics Optimization
- Fault Detection and Control Systems
- Industrial Technology and Control Systems
- Combustion and flame dynamics
- Risk and Safety Analysis
- Pharmaceutical studies and practices
- Hemoglobinopathies and Related Disorders
- Bacterial Infections and Vaccines
- Optimization and Packing Problems
- Advanced Combustion Engine Technologies
- Machine Fault Diagnosis Techniques
- Advanced Sensor and Control Systems
- Heat transfer and supercritical fluids
Beijing Tian Tan Hospital
2022-2024
Capital Medical University
2022-2024
Guangxi University
2020-2021
Tianjin Internal Combustion Engine Research Institute
2021
Tianjin University
2021
Objective: The primary objective of this study revolves around the development a population pharmacokinetic (PPK) model for vancomycin in neonatal subjects, with providing theoretical basis judicious therapeutic interventions. Methods: In study, retrospective collection encompassed 75 patients, contributing to total 89 blood concentration monitoring datasets. establishment PPK is carried out utilizing nonlinear mixed effects methodology. was constructed employing one‐compartment proportional...
Matching status (failure or success) between logistics vehicles and cargoes during transport operation influences the decisions of owners on scheduling. It is therefore essential to predict specific matching probability vehicle-cargo (VCM). This paper defines VCM probability, formulates problem, proposes a method this based Bayesian network. The business (vehicle goods resources) distribution, degree, priority are introduced. By mapping distribution results network nodes degree as...
Lamotrigine is a new antiepileptic drug with substantial interindividual variability in its pharmacokinetics and therapeutic responses. This study aimed to develop population pharmacokinetic (PPK) models of lamotrigine N2-glucuronide metabolites for model-informed individualized therapy.
Objective: Vancomycin is commonly used in postoperative neurosurgical patients for empirical anti-infective treatment due to the low success rate of bacterial culture cerebrospinal fluid (about 20%) and high mortality intracranial infection. At conventional doses, target achievement vancomycin trough concentration pharmacokinetics varies greatly these patients, which often leads failure. The objective this study was establish a population pharmacokinetic (PPK) model precision medicine....
Abstract According to the characteristics of actual transportation packing problem, three-dimensional vehicle problem with path constraints is studied, and optimal model established, then taboo search added genetic algorithm solve problem. The performance verified by example analysis. experimental result shows that hybrid can obtain an approximate solution higher quality than ordinary algorithm, indicating has a better great help in improving utilization work efficiency.