Fengchen Zhang

ORCID: 0009-0009-7826-7040
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Research Areas
  • Concrete and Cement Materials Research
  • Magnesium Oxide Properties and Applications
  • Diet and metabolism studies
  • ZnO doping and properties
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Advanced Photocatalysis Techniques
  • Ga2O3 and related materials
  • Microbial Applications in Construction Materials
  • Quantum Dots Synthesis And Properties
  • Cerebrospinal fluid and hydrocephalus
  • Gut microbiota and health
  • Thermal Regulation in Medicine
  • Innovative concrete reinforcement materials
  • Neonatal and fetal brain pathology
  • Petroleum Processing and Analysis
  • Photorefractive and Nonlinear Optics
  • Covalent Organic Framework Applications
  • Metabolism and Genetic Disorders
  • Glioma Diagnosis and Treatment
  • Traumatic Brain Injury Research
  • Grouting, Rheology, and Soil Mechanics
  • Tryptophan and brain disorders
  • Food Supply Chain Traceability
  • Underwater Vehicles and Communication Systems
  • MXene and MAX Phase Materials

Shanghai Jiao Tong University
2018-2024

Hohai University
2011-2024

China Three Gorges University
2023-2024

Huaqiao University
2023

Renji Hospital
2018-2023

Naval University of Engineering
2022

Lanzhou University of Technology
2014

Wuhan University of Technology
2009

Complex mechanisms participate in microglial activation after a traumatic brain injury (TBI). TBI can induce autophagy and apoptosis neurons glial cells, moderate hypothermia plays protective role the acute phase of TBI. In present study, we evaluated effect on investigated possible roles autophagy/apoptosis toll-like receptor 4 (TLR4).The model was induced with fluid percussion device. Moderate achieved under general anesthesia by partial immersion water bath for h. All rats were killed 24...

10.1186/s12974-018-1315-1 article EN cc-by Journal of Neuroinflammation 2018-09-20

Abstract Aims This study aimed to investigate the relationship between microglial metabolism and neuroinflammation by examining impact of citrate accumulation in microglia its potential regulation through Cs K215 hypoacetylation. Methods Experimental approaches included assessing enzyme activity K215Q mutation investigating inhibitory effects hesperidin, a natural flavanone glycoside, on synthase. Microglial phagocytosis expression pro‐inflammatory cytokines were also examined relation...

10.1111/cns.14567 article EN cc-by CNS Neuroscience & Therapeutics 2024-02-01

The impact of hypothermia on the impaired drainage function glymphatic system in traumatic brain injury (TBI) is not understood.Male Sprague-Dawley rats undergoing controlled cortical (CCI) were subjected to or normothermia treatment. sham surgery without CCI used as control. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) with intrathecal administration low- and high-molecular-weight contrast agents (Gd-DTPA hyaluronic acid conjugated Gd-DTPA) was performed after TBI head...

10.3389/fnins.2023.1061039 article EN cc-by Frontiers in Neuroscience 2023-02-02

The underwater wireless sensor network is an important component of the three-dimensional monitoring system. Due to high bit error rate, delay, low bandwidth, limited energy, and dynamic networks, it very difficult realize efficient reliable data transmission. Therefore, this paper posits that not enough design routing algorithm only from perspective transmission environment; comprehensive should also be combined with application. An edge prediction-based adaptive (EP-ADTA) proposed can...

10.3390/s22155490 article EN cc-by Sensors 2022-07-23

10.1007/s11595-011-0268-3 article EN Journal of Wuhan University of Technology-Mater Sci Ed 2011-06-01

Glioblastoma multiforme (GBM) is well known as a highly aggressive brain tumor subtype. Here, we show that overexpression (OE) of dematin actin-binding protein (DMTN) inhibits GBM proliferation and invasion by affecting cell cycle regulation actin remodeling, respectively. RT-qPCR, western blotting, immunohistochemical (IHC) staining demonstrated significant reduction in DMTN expression gliomas, especially high-grade gliomas (HGG) compared with normal brains, which correlates worse survival...

10.1016/j.yexcr.2022.113196 article EN cc-by-nc-nd Experimental Cell Research 2022-05-10

Abstract Repetitive mild traumatic brain injury (rmTBI) is associated with a range of neural changes which characterized by axonal and neuroinflammation. Ketogenic diet (KD) regarded as potential therapy for facilitating recovery after moderate-severe (TBI). However, its effect on rmTBI has not been studied. In this study, we evaluated the anti-neuroinflammation effects KD in adolescent mice explored mechanisms. Experimentally, specific pathogen-free (SPF) male C57BL/6 received sham surgery...

10.21203/rs.3.rs-1155536/v1 preprint EN cc-by Research Square (Research Square) 2022-01-28

The glymphatic system has recently been shown to clear brain extracellular solutes and can be extensively impaired after traumatic injury (TBI). Despite hypothermia being identified as a protective method for the injured via minimizing formation of edema in animal study, little is known about how affects following TBI. We use dynamic contrast-enhanced MRI (DCE-MRI) cisterna magna infusion with low molecular weight contrast agent track transport male Sprague–Dawley rats TBI treatment...

10.3389/fneur.2022.957055 article EN cc-by Frontiers in Neurology 2022-10-20

To address the issues of low strength, poor water stability, and hazardous substance leaching associated with using phosphogypsum (PG) as a direct road-based material, traditional approach involves employing inorganic cementing materials to stabilize PG, effectively addressing problems. This study innovatively utilizes xanthan gum (XG) sodium methylsiliconate (SM) curing agents for PG solve above An organic agent stabilized was prepared by dry mixing XG PG. The unconfined compressive...

10.3390/ma16206766 article EN Materials 2023-10-19

In order to improve the management of information slaughterhouse and automation, ensure safety pork production, design wireless RFID reader devices system based on CC2530 by integrating radio frequency identification technology ZigBee network which is used in pig slaughter traceability information.Use MF RC522 build a reader, software Visual Studio 2008 platform.System integration tests showed that use transmission can transmit data with two-way so applications more flexible.The has high...

10.2991/lemcs-14.2014.229 article EN cc-by-nc Advances in intelligent systems research/Advances in Intelligent Systems Research 2014-01-01

This paper reports the effect of annealing temperature on morphology, properties and photocatalytic efficiency Ti/Ga co-doped ZnO (TGZ) nanoparticles prepared by sol-gel method. The were characterized in terms their structure, composition, optical several techniques. detailed characterization confirmed that are related to temperature. When is low, impurities exist. With increase temperature, pure TGZ formed. reaches a certain TiZn2O4 spinel will be greatly affects particle size, band gap,...

10.2139/ssrn.4261883 article EN SSRN Electronic Journal 2022-01-01

This paper reports the effect of annealing temperature on morphology, properties and photocatalytic efficiency Ti/Ga co-doped ZnO (TGZ) nanoparticles prepared by sol-gel method. The were characterized in terms their structure, composition, optical several techniques. detailed characterization confirmed that are related to temperature. When is low, impurities exist. With increase temperature, pure TGZ formed. reaches a certain TiZn2O4 spinel will be greatly affects particle size, band gap,...

10.2139/ssrn.4233199 article EN SSRN Electronic Journal 2022-01-01
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