A5033551577- Veterinary medicine and infectious diseases
- Virology and Viral Diseases
- Immune Response and Inflammation
- Zebrafish Biomedical Research Applications
- Animal Disease Management and Epidemiology
- Microbial infections and disease research
- Animal Virus Infections Studies
- Influenza Virus Research Studies
- Virus-based gene therapy research
- Immunotherapy and Immune Responses
Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini"
2020-2022
In the last two years, there have been three major epidemic seasons in territory of European Union and HPAI epizootic 2021-2022 is most severe recent history. Italy, disease was introduced to dense poultry areas with serious economic consequences for entire sector. Lombardy, analysis risk factors carried out, also taking into account density domestic birds. affected areas, 66.7% outbreaks occurred highest likelihood an outbreak occurring increased increase birds per km2. cells 10 × km a...
Abstract Dolphin morbillivirus (DMV) is a pathogen of great concern in free-ranging cetaceans. Confirmation and staging infections rely on histology immunohistochemistry (IHC), following molecular detection. As at the present time no specific antibodies (Abs) against DMV are available, two heterologous Abs have been used worldwide for examinations One monoclonal Ab (MoAb) prepared N protein canine distemper virus (CDV), whereas other polyclonal raised rabbits rinderpest (RPV). Both known to...
According to the 3Rs principle (Replacement, Refinement, Reduction), this study aims find alternative methods evaluate toxicity of autogenous vaccines. Currently in Italy Istituti Zooprofilattici Sperimentali (II.ZZ.SS.) must perform vivo test for each lot vaccine produced as laid down Decree 17 March 1994. This paper describes two vitro assessing The first is MTT based on metabolic reaction tetrazolium salt vital cells. second method measurement IL-1ß production by macrophages, obtained...
Making the zebrafish embryo available to be able share it between different laboratories groups could pave way for this animal model with aim of disseminating and promoting use application in scientific research.
Making the zebrafish embryo available to be able share it between different laboratories groups could pave way for this animal model with aim of disseminating and promoting use application in scientific research.