Abstract Aims The Stress Hyperglycemia Ratio (SHR) potently predicts adverse outcomes in patients with cardiovascular and cerebrovascular diseases. However, the relationship between SHR short-term mortality risk a first diagnosis of acute myocardial infarction (AMI) remains contentious. This study sought to understand better AMI. Methods We conducted cohort using data from 1961 AMI MIMIC-IV (version 2.2) database. Patients were divided into three groups based on tertiles. Cox proportional...

Background To describe the burden and examine transnational inequities in overall cardiovascular disease (CVD) ten specific CVDs across different levels of societal development. Methods Estimates disability-adjusted life-years (DALYs) for each their 95% uncertainty intervals (UI) were extracted from Global Burden Diseases (GBD). Inequalities distribution CVD burdens quantified using two standard metrics recommended absolute relative inequalities by World Health Organization (WHO), including...

Abstract Although in vitro experiments have demonstrated the potential of flavonoid compounds regulating blood pressure, there is still a lack evidence from large population studies. We conducted cross‐sectional study using National Health and Nutrition Examination Survey to investigate relationship between intake levels (natural log transformation) hypertension events. A total 15 752 participants aged over 20 years were included, weighted multivariable logistic regression analysis was...

Objective The association between the Triglyceride-Glucose (TyG) Index and mortality rates in patients with cardiovascular disease (CVD) remains unclear. This study investigates TyG index incidence of all-cause CVD-specific among individuals a history CVD. Design Population-based cohort study. Setting Data were sourced from US National Health Nutrition Examination Survey (2007–2018) linked data, follow-up continuing until 31 December 2019. Participants population comprised 3422 aged 20 years...

Introduction: To provide a comprehensive assessment of temporal trends in migraine prevalence among women childbearing age (WCBA) at global, regional and national levels from 1992 to 2021, with particular emphasis on examining the associations between patterns age, period birth cohort effects across different sociodemographic index (SDI) regions. Methods: We conducted secondary analysis data Global Burden Disease Study 2021. Migraine estimates 95% uncertainty intervals (UI) for WCBA were...

Abstract For over a century, flour bleaching agents—chlorine gas, benzoyl peroxide (BPO), and nitrogen peroxide—have transformed dietary staple into public health gamble. Originating in 1901 England to mimic “naturally aged” flour, these chemicals degrade nutrients like vitamins E A, generate carcinogenic free radicals, leave residues linked liver damage chronic inflammation. Despite early warnings bans the EU, UK, China, Turkey, U.S. perpetuates this practice, shielded by 1914 Supreme Court...

This study aimed to describe the prevalence, deaths, and disability-adjusted life-years (DALYs) of hypertensive heart disease (HHD) at global, regional, national levels analyze epidemiological trends.

Serum vitamin D deficiency is common in the patients with cardiovascular disease (CVD), but association between serum levels and risk of all-cause mortality CVD controversial.This study aimed to understand better 25(OH)D status prior CVD.We conducted a cohort using data from National Health Nutrition Examination Survey 2007 2018 investigate multivariate Cox regression models, further subgroup analyses interactions smooth curve fitting address possible nonlinearities.A total 3220 participants...

Abstract Aim Epidemiological research on hypertensive heart disease (HHD) in women of childbearing age (WCBA) remains scarce. Our objective is to describe the current prevalence HHD WCBA at global, regional, and national levels analyze its temporal trends from 1990 2019. Methods was defined as aged 15–49 years. Estimates 95% Uncertainty Intervals (UI) numbers for seven groups (15–19, 20–24, 25–29, 30–34, 35–39, 40–44, 45–49 years) were extracted 2019 Global Burden Disease Study (GBD). The...

Background Our objective is to describe the current prevalence and death of ischemic heart disease (IHD) in women childbearing age (WCBA) at global, regional, national levels analyze its temporal trends from 1990 2019. Methods WCBA was defined as aged 15–49 years. Estimates 95% Uncertainty Intervals (UI) IHD numbers for seven groups were extracted 2019 Global Burden Disease Study. The age-standardized rate (ASPR ASDR) estimated using direct age-standardization method. Joinpoint regression...

Abstract Background: To describe the burden and examine transnational inequities in overall cardiovascular disease (CVD) ten specific CVDs across different levels of societal development. Methods: Estimates disability-adjusted life-years (DALYs) for each their 95% uncertainty intervals (UI) were extracted from Global Burden Diseases (GBD). Inequalities distribution CVD burdens quantified using two standard metrics, including Slope Index Inequality (SII) Concentration Index. Results: Between...

Abstract Background: Epidemiological research on hypertensive heart disease (HHD) in women of childbearing age (WCBA) remains scarce China. We aim to describe the current prevalence HHD China and analyze its temporal trends over past 30 years. Methods: WCBA was defined as The age-standardized rate (ASPR) estimated. Joinpoint regression age-period-cohort methods were used from 1990 2019. Results: In 2019, among 0.171 million (95% UI: 0.105 0.262). From there an annual net drift 0.65% CI: 0.52...

Abstract Background The relationship between HGI and short-term mortality risk in patients with a first diagnosis of acute myocardial infarction (AMI) remains unclear. This study sought to understand better the AMI. Methods We conducted cohort using data from 1961 AMI MIMIC-IV (version 2.2) database. Patients were divided into four groups based on quartiles. Cox proportional hazards model two-segmented used elucidate nonlinear mortality. Results Of surveyed population, 175 (8.92%) died...

Abstract The prevalence of Essential Hypertension (EH) is increasing globally, and the effectiveness pharmacological treatments remains far from ideal. Combining Mendelian Randomization (MR) to identify potential drug targets may be key reducing disease burden developing treatments. We utilized UK Biobank cohort (ncase = 54358, ncontrol 408652) extract summary statistics for EH further validated in FinnGen 92462, 265626). Cis-expression quantitative trait loci (cis-eQTL) available druggable...

Abstract Background: Epidemiological studies on cardiovascular diseases (CVD) among women of childbearing age (WCBA) remain scarce. Our research aims to delineate the prevalence trends CVD within this population over past three decades, considering age, period, and birth cohort dynamics. Methods: Estimates for WCBA, along with their 95% uncertainty intervals (UI), were extracted from Global Burden Diseases 2019 (GBD2019). An age-period-cohort (APC) model was utilized assess annual percentage...

<title>Abstract</title> Background Although in vitro experiments have demonstrated the potential of flavonoid compounds regulating blood pressure, there is still a lack evidence from large population studies to confirm it. We conducted cross-sectional study using National Health and Nutrition Examination Survey investigate relationship between intake levels hypertension events. Method A total 15,752 participants aged over 20 years were included, weighted multivariable logistic regression...

<title>Abstract</title> <bold>Aims:</bold>The Stress Hyperglycemia Ratio (SHR) potently predicts adverse outcomes in patients with cardiovascular and cerebrovascular diseases. However, the relationship between SHR short-term mortality risk a first diagnosis of acute myocardial infarction (AMI) remains contentious. This study sought to understand better AMI. <bold>Methods:</bold>We conducted cohort using data from 1961 AMI MIMIC-IV (version 2.2) database. Patients were divided into three...

Abstract Background Serum vitamin D deficiency is common in the patients with cardiovascular disease (CVD), but association between serum levels and risk of all-cause mortality CVD controversial. Objective This study aimed to understand better 25(OH)D status prior CVD. Method We conducted a cohort using data from National Health Nutrition Examination Survey 2007–2018 investigate multivariate Cox regression models, further subgroup analyses interactions smooth curve fitting address possible...