Reena John

ORCID: 0009-0009-8770-6682
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About
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Research Areas
  • Ocular Surface and Contact Lens
  • Biosensors and Analytical Detection
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • vaccines and immunoinformatics approaches
  • Advanced Biosensing Techniques and Applications
  • Salivary Gland Disorders and Functions
  • SARS-CoV-2 and COVID-19 Research
  • Animal Virus Infections Studies
  • Advanced Glycation End Products research
  • Hepatitis Viruses Studies and Epidemiology
  • Bacterial Infections and Vaccines
  • SARS-CoV-2 detection and testing
  • Connexins and lens biology
  • Heme Oxygenase-1 and Carbon Monoxide
  • Advanced Proteomics Techniques and Applications
  • Poxvirus research and outbreaks
  • Ocular Infections and Treatments
  • Vibrio bacteria research studies
  • Computational Drug Discovery Methods
  • Proteoglycans and glycosaminoglycans research
  • Glaucoma and retinal disorders
  • COVID-19 and healthcare impacts
  • Acute Myocardial Infarction Research
  • Hepatitis B Virus Studies
  • Ocular Diseases and Behçet’s Syndrome

Government Medical College
2016-2025

Manipal Academy of Higher Education
2020-2024

Government Medical College
2020

From March to June 2021, India experienced a deadly second wave of COVID-19, with an increased number post-vaccination breakthrough infections reported across the country. To understand possible reason for these breakthroughs, we collected 677 clinical samples (throat swab/nasal swabs) individuals from 17 states/Union Territories country who had received two doses (n = 592) and one dose 85) vaccines tested positive COVID-19. These cases were telephonically interviewed data analyzed. A total...

10.3390/v13091782 article EN cc-by Viruses 2021-09-07

Tuberculosis (TB) is a leading cause of mortality and morbidity in India. While India moving towards ending TB, estimating the TB burden still challenge. This study aims to assess prevalence pathologically active lungs deceased persons undergoing autopsy. The group consisted all cases autopsy during period (May 2021-October 2022). Tissue bits from apex both were collected Gross pathological examination microscopy tissue done. Proportion 95% confidence intervals estimated for TB. A chi-square...

10.7759/cureus.81632 article EN Cureus 2025-04-02

Abstract Acute myocardial infarction (MI) is found to be a major causative factor for global mortality and morbidity. This situation demands necessity of developing efficient rapid diagnostic tools detect acute MI. Raman spectroscopy non-destructive optical technique, which has high potential in probing biochemical changes clinical samples during initiation progress diseases. In this work, blood was taken as the sample examine inflammation MI patients using spectroscopy. Ratio peak...

10.1007/s10103-022-03604-1 article EN cc-by Lasers in Medical Science 2022-07-12

Abstract During March to June 2021 India has experienced a deadly second wave of COVID-19 with an increased number post-vaccination breakthrough infections reported across the country. To understand possible reason these breakthroughs we collected 677 clinical samples (throat swab/ nasal swabs) individuals who had received two doses (n=592) and one dose (n=85) vaccines (Covishield Covaxin,) tested positive for COVID-19, from 17 states/Union Territories These cases were telephonically...

10.1101/2021.07.13.21260273 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2021-07-15

Abstract Introduction: Free-living amoeba is ubiquitous in fresh water, mud, and moist soil; although seldom pathogenic to humans, Naegleria fowleri , Acanthamoeba spp., Balamuthia spp. are known cause infections of the central nervous system. Methods: We report two interesting cases, both which presented with a rapid-onset fulminant course. The first case details 36-year-old male history surgically corrected nasal bone fracture 15 years back, who acute onset fever, headache convulsions....

10.4103/tp.tp_37_23 article EN Tropical parasitology 2024-07-01

Tear fluid contains organic and inorganic constituents, variations in their relative concentrations could provide valuable information can be useful for the detection of several ophthalmological diseases.

10.1039/d3ra04389d article EN cc-by-nc RSC Advances 2023-01-01

In this paper the potential of optical spectroscopy based techniques for regular screening and early diagnosis "Killer" diseases (various types cancers, cardiovascular diseases, etc.) is discussed with focus on routine use under low-resource settings. A brief account work carried out in our laboratory to design, assemble optimize Laser Induced Fluorescence (LIF) devices screening, discrimination premalignant/malignant conditions oral other cancers presented. An ultra-sensitive protein...

10.18287/jbpe20.06.020309 article EN cc-by Journal of Biomedical Photonics & Engineering 2020-06-30

Neisseria meningitidis is one of the primary pathogens pyogenic meningitis and has potential to cause large epidemics. There are 13 serogroups N. that have been identified, six which (A, B, C, W, X Y) can We report a case acute caused by in six-month-old male child who presented with fever four-day duration irritable cry for day. was isolated from his blood using automated culture system. Latex agglutination test antigen positive cerebrospinal fluid. The baby responded well Ceftriaxone but...

10.4103/0972-1282.194947 article EN Journal of The Academy of Clinical Microbiologists 2024-08-17

ABSTRACT Infections caused due to zoonotic hookworms are rare and often under reported. Here we report a case of diarrheal disease by Ancylostoma ceylanicum , an important emerging hookworm. There is limited knowledge about the epidemiology burden A. infections in Kerala. A 50-year-old male patient presented with complaints loose stools for past five weeks. The laboratory investigations revealed high total WBC count eosinophil count. Diagnostic colonoscopy showed numerous worms which were...

10.4103/ijpm.ijpm_385_23 article EN cc-by-nc-sa Indian Journal of Pathology and Microbiology 2024-02-19

Cataract is the common cause of reversible blindness and visual impairment. It in low socioeconomic groups developing countries. This paper describes application an assembled High-Performance Liquid Chromatography-LED-Induced Fluorescence (HPLC-LED-IF) system to study protein profiles lens fluid samples from cataract patients with without diabetes. The HPLC-LED-IF our laboratory was used record obtained volunteers having diabetes who have undergone surgery. Statistical analyses such as...

10.18287/jbpe24.10.030302 article EN cc-by Journal of Biomedical Photonics & Engineering 2024-08-17

Purpose The study showcased the application of lab-assembled HPLC-LED-IF system to analyze proteins in tear fluid samples collected from individuals diagnosed with primary open-angle glaucoma (POAG).

10.1080/02713683.2023.2289862 article EN cc-by-nc-nd Current Eye Research 2023-12-11

Population Health ManagementVol. 24, No. 6 Points of ViewFree AccessDisruptive Resilience: Harnessing Leadership to Build a More Equitable Care System After COVID-19Julian A. Mitton, Brisa Urquieta de Hernandez, Nisha Pasupuleti, Kimm Hurley, Reena John, and Alisahah ColeJulian MittonAddress correspondence to: Julian MD, MPH, Health, CommonSpirit 185 Berry Street 200, San Francisco, CA 94107, USA E-mail Address: [email protected]Population California, USA.Search for more papers by this...

10.1089/pop.2021.0041 article EN Population Health Management 2021-03-30

BACKGROUND: Hepatitis E virus (HEV) is emerging globally as a leading cause of an acute and generally self-limited hepatitis but associated with higher mortality, especially during pregnancy. AIM: The purpose this study was to estimate the seroprevalence infection among adults no previous history jaundice/liver disease, in tertiary care centre at Thrissur. STUDY SETTING AND DESIGN: Hospital based cross sectional carried out Government Medical College, MATERIALS METHODS: Anti-HEV IgG detected...

10.4103/jacm.jacm_33_19 article EN Journal of The Academy of Clinical Microbiologists 2020-01-17
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