Jitendra Narayan
A5062960505- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- COVID-19 epidemiological studies
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Virology and Viral Diseases
- Animal Virus Infections Studies
- COVID-19 Clinical Research Studies
- COVID-19 diagnosis using AI
- Molecular Biology Techniques and Applications
- Rabies epidemiology and control
- Respiratory viral infections research
- Vector-borne infectious diseases
- vaccines and immunoinformatics approaches
- Viral Infections and Immunology Research
- Child Nutrition and Water Access
- Malaria Research and Control
- Bacteriophages and microbial interactions
- Lymphoma Diagnosis and Treatment
- Birth, Development, and Health
- Food Security and Health in Diverse Populations
- Viral-associated cancers and disorders
- Influenza Virus Research Studies
- Viral gastroenteritis research and epidemiology
- Vaccine Coverage and Hesitancy
Ministry of Health and Family Welfare
2018-2024
Government of India
2020-2024
Indian Council of Medical Research
2021-2023
Department of Health Research
2020
Nepean Hospital
2012
From March to June 2021, India experienced a deadly second wave of COVID-19, with an increased number post-vaccination breakthrough infections reported across the country. To understand possible reason for these breakthroughs, we collected 677 clinical samples (throat swab/nasal swabs) individuals from 17 states/Union Territories country who had received two doses (n = 592) and one dose 85) vaccines tested positive COVID-19. These cases were telephonically interviewed data analyzed. A total...
We report here a Nipah virus (NiV) outbreak in Kozhikode district of Kerala state, India, which had caused fatal encephalitis 12-year-old boy and the response, led to successful containment disease related investigations. Quantitative real-time reverse transcription (RT)-PCR, ELISA-based antibody detection, whole genome sequencing (WGS) were performed confirm NiV infection. Contacts index case traced isolated based on risk categorization. Bats from areas near epicenter sampled for throat...
The current investigation was conducted with the objective to develop an epidemiological case definition of possible severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) re-infection and assess its magnitude in India. for SARS-CoV-2 developed from literature review data on viral kinetics. For achieving second objective, individuals who satisfied were contacted telephonically. Taking available evidence into consideration, our study defined as any individual tested positive two...
The number of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) cases is increasing in India. This study looks upon the geographic distribution virus clades and variants circulating different parts India between January August 2020. NPS/OPS from representative positive states union territories were collected every month through VRDLs country analyzed using next-generation sequencing. Epidemiological analysis 689 SARS-CoV-2 clinical samples revealed GH GR to be predominant northern...
A retrospective study was undertaken to investigate the circulating dengue virus (DENV) serotypes and genotypes in India 2018.In total, 4963 samples referred research diagnostic laboratories (n=21), Indian Council of Medical Research-National Institute Virology (ICMR-NIV) ICMR-NIV field units (n=2) for diagnosis 2018 were tested using a real-time reverse transcription polymerase chain reaction assay presence DENV serotypes. Representative sequenced envelope (E) gene.Regional diversity...
Background & objectives: Public health and diagnostic laboratories are facing huge sample loads for COVID-19 diagnosis by real-time reverse transcription-polymerase chain reaction (RT-PCR). High sensitivity of optimized RT-PCR assays makes pooled testing a potentially efficient strategy resource utilization when positivity rates particular regions or groups individuals low. We report here comparative analysis 5- 10-sample pools across 10 in India. Methods: Ten virus research (VRDLs)...
Over time, COVID-19 testing has significantly declined across the world. However, it is critical to monitor virus through surveillance. In late 2020, WHO released interim guidance advising use of existing Global Influenza Surveillance and Response System (GISRS) for integrated surveillance influenza SARS-CoV-2.In July 2021, we initiated a pan-India SARS-CoV-2 geographically representative network Virus Research Diagnostic Laboratories (VRDLs) 26 hospital laboratory sites 70 community sites....
Background & objectives: An outbreak of respiratory illness unknown aetiology was reported from Hubei province Wuhan, People's Republic China, in December 2019. The attributed to a novel coronavirus (CoV), named as severe acute syndrome (SARS)-CoV-2 and the disease COVID-19. Within one month, cases were 25 countries. In view viral strain with high morbidity, establishing early countrywide diagnosis detect imported became critical. Here we describe role network VRDLs Methods: Indian Council...
Sudden emergence and rapid spread of COVID-19 created an inevitable need for expansion the laboratory testing network across world. The strategy to test-track-treat was advocated quick detection containment disease. Being second most populous country in world, India challenged make available accessible all parts country. molecular augmented expeditiously, number laboratories increased from one January 2020 2951 till mid-September, 2021. This warranted have inbuilt systems quality control/...
Abstract The pandemic of COVID‐19 has caused enormous fatalities worldwide. Serological assays are important for detection asymptomatic or mild cases COVID‐19, and sero‐prevalence vaccine efficacy studies. Here, we evaluated compared the performance seven commercially available enzyme‐linked immunosorbent assay (ELISA)s anti‐severe acute respiratory syndrome corona virus 2 (SARS‐CoV‐2) immunoglobulin G (IgG). ELISAs were with a characterized panel 100 serum samples from qRT‐PCR confirmed...
The diagnosis of scrub typhus (ST) is usually done using enzyme-linked immunosorbent assay (ELISA) due to its ease performance and reading objectivity. cut-off value for ELISA needs be calculated each geographical location as it depends on zonal endemicity the disease. This study was, therefore, undertaken calculate pan-India anti-Orientia tsutsugamushi (OT) immunoglobulin M (IgM) by ELISA.Samples from cases (cases ST) controls (voluntary, consenting, healthy adults) were collected a network...
To expand the measles and rubella laboratory network of India by integrating new laboratories.
Background & objectives Genetic analysis of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) strains circulating in India during 2020-2022 was carried out to understand the evolution potentially expanding and divergent clades. Methods SARS-CoV-2 sequences (n=612) randomly selected from among samples collected through a nationwide network Virus Research Diagnostic Laboratories 2020 (n=1532) Indian available Global Initiative on Sharing All Influenza Data March 2020-March 2022...
Abstract Introduction : Kaposi's Sarcoma (KS) is an angioproliferative disease, which affects the skin and mucous membranes KS tumours usually follow indolent course of progression patients present with asymptomatic papules or nodules that are commonly found in lower limbs. Radiation therapy most common form treatment due to disease response rates. Case presentation In November 2008, a 58‐year‐old male patient presented Nepean Cancer Care Centre (NCCC) clinic small on right second left fifth...
Dengue, chikungunya and Japanese encephalitis are the most common arthropod-borne viral diseases in India. Due to overlapping clinical symptoms, accurate, high-quality timely laboratory-based differential diagnosis is essential for control containment of outbreaks. This commonly done by detection IgM antibodies serum using enzyme-linked immunosorbent assays. The Resource Centre Virus Research Diagnostic Laboratories (VRDLs) Pune, India organized an external quality assurance (EQA) study...
Abstract Background We report here a Nipah virus (NiV) outbreak in Kozhikode district of Kerala state, India which had caused fatal encephalitis an adolescent male and the response led to successful containment disease related investigations. Methods Quantitative real-time RT-PCR, ELISA based antibody detection whole genome sequencing were performed confirm infection. Contacts index case traced isolated on risk categorization. Bats from areas near epicenter sampled for throat swabs, rectal...