A5100401034- Parasitic infections in humans and animals
- Cardiomyopathy and Myosin Studies
- Congenital Anomalies and Fetal Surgery
- Hip and Femur Fractures
- Pelvic and Acetabular Injuries
- Spinal Fractures and Fixation Techniques
- Renal cell carcinoma treatment
- Cancer-related molecular mechanisms research
- Lung Cancer Treatments and Mutations
- Traditional Chinese Medicine Studies
- Atrial Fibrillation Management and Outcomes
- Gastric Cancer Management and Outcomes
- Acute Myocardial Infarction Research
- Cardiac electrophysiology and arrhythmias
- Medical Research and Treatments
- Osteoarthritis Treatment and Mechanisms
- Infectious Diseases and Tuberculosis
- Bone fractures and treatments
- Cardiovascular Effects of Exercise
- Head and Neck Cancer Studies
- Helicobacter pylori-related gastroenterology studies
- Orthopedic Surgery and Rehabilitation
- Intraocular Surgery and Lenses
- Pregnancy-related medical research
- Meningioma and schwannoma management
First Affiliated Hospital of Bengbu Medical College
2025
Hebei Medical University
2022-2024
Second Hospital of Hebei Medical University
2022-2024
Xi'an Honghui Hospital
2013-2024
Xi'an Jiaotong University
2013-2024
Wuhan University
2011-2024
Tianjin Huanhu Hospital
2014-2024
Qilu Hospital of Shandong University
2024
The University of Adelaide
2023-2024
First Hospital of Jiaxing
2024
The genetic diversity of Yersinia pestis , the etiologic agent plague, is extremely limited because its recent origin coupled with a slow clock rate. Here we identified 2,326 SNPs from 133 genomes Y. strains that were isolated in China and elsewhere. These define genealogy since most common ancestor. All but 28 these represented mutations happened only once within genealogy, they distributed essentially at random among individual genes. Only seven genes contained significant excess...
Deep vein thrombosis in bilateral lower extremities after hip fracture: a retrospective study of 463 patients Bin-Fei Zhang,* Xing Wei,* Hai Huang, Peng-Fei Wang, Ping Liu, Shuang-Wei Qu, Jia-Hao Li, Hu Yu-Xuan Cong, Yan Zhuang, Kun Zhang Department Orthopedic Trauma, Hong-Hui Hospital, Xi'an Jiaotong University College Medicine, Beilin District, Xi'an, Shaanxi, China *These authors contributed equally to this work Objective: To investigate the incidences deep (DVT) before and operation...
Abstract Cuproptosis, a newly discovered programmed cell death induced by copper ions, is associated with the progression and drug resistance of various tumors. Docetaxel plays vital role as first‐line chemotherapeutic agent for advanced prostate cancer; however, most patients end up cancer because inherent or acquired resistance. Herein, we examined cuproptosis in to docetaxel. We treated lines elesclomol–CuCl 2 , well performed analyses CCK8, colony formation tests, cycle flow assay,...
Abstract Background Sequential analysis of atrial electromechanical coupling (P‐A) by Doppler tissue imaging (DTI) might provide important insight into the mechanisms paroxysmal fibrillation (PAF). Hypothesis The purpose this study was to evaluate P‐A and dispersion P‐A, analyze influential factors P‐A. Methods One hundred ten patients with PAF 87 normal controls were enrolled. Using DTI, time intervals from beginning P‐wave onset atrioventricular ring motion related contraction measured....
Ulcerative colitis is a worldwide epidemic, chronic and nonspecific inflammatory bowel disease. Fecal microbiota Transplantation(FMT) as new method has been used in clinical treatment for UC, however the molecular mechanisms behind this effect have yet to be fully understood. Animal models provide means test whether FMT promote recovery of colon inflammation Administration 2 % Dextra sulfate sodium(DSS) 7 d successfully induced acute associated with diarrhea, hematochezia shortening, well...
Abstract Background Metabolism reprogramming plays a vital role in glioblastoma (GBM) progression and recurrence by producing enough energy for highly proliferating tumor cells. In addition, metabolic is crucial growth immune‐escape mechanisms. Epidermal factor receptor ( EGFR ) amplification EGFR‐vIII mutation are often detected GBM cells, contributing to the malignant behavior. This study aimed investigate functional of pathway on fatty acid metabolism remodeling generation. Methods...
Abstract Parkinson’s disease (PD) is a progressive neurodegenerative characterized by mitochondrial dysfunction and accumulation of alpha-synuclein (α-Syn)-containing protein aggregates known as Lewy bodies (LB). Here, we investigated the entry α-Syn into mitochondria to cause loss cellular fitness in vivo. We show that expressed yeast human cells constitutively imported mitochondria. In transgenic mouse model, level endogenous dopaminergic neurons microglia increases with age. The degraded...
Angiotensin II (Ang II) and its receptor, receptor type 1 (AGTR1), have been implicated in the proliferation of cancer cells across various tumor types. This study aims to examine impact Ang AGTR1 on esophageal squamous cell carcinoma (ESCC) cells. The clonogenicity were evaluated through Clone Formation Cell Counting Kit-8 (CCK-8) assays. migration invasion determined utilizing Transwell Flow cytometry was employed analyze cycle. Additionally, investigate expressions genes associated with...
Background Elevated high‐sensitivity C‐reactive protein (hs CRP ) has been associated with increased risks of adverse outcomes various cardiovascular diseases. The relationship between hs and the prognosis hypertrophic cardiomyopathy remains to be evaluated. Methods Results study used an observational cohort methodology. A total 490 patients were enrolled in Fuwai Hospital from 2001 2011 followed for 3.7±2.0 years. According risk category , subjects high group (>3.0 mg/L) had a higher...
Esophageal squamous cell carcinoma (ESCC) is one of the most refractory malignancies worldwide. Mitogen-activated protein kinase 3 (MAP2K3) has a contradictory role in tumor progression, and function expression patterns MAP2K3 ESCC remain to be determined. We found that downregulated ESCC, downregulation correlated with clinically poor survival. inhibited proliferation invasion vitro vivo. suppressed STAT3 activation. Mechanistically, MAPSK3 interacted MDM2 promote degradation via...
Background: A major subgroup of patients with temporomandibular joint (TMJ) disorders have masticatory muscle hypersensitivity. To study myofacial pain, a number preclinical models been developed to induce myogenic pain the masseter muscle, one four muscles involved in mastication. The currently used models, however, generate that decreases over time and only lasts from hours weeks hence are not suitable for studying chronicity TMJ disorders. Here we report model constant orofacial months....
Red blood cells (RBCs), which function as material transporters in organisms, are rich materials that exchanged with metabolically active tumor cells. Recent studies have demonstrated can regulate biological changes RBCs, including influencing differentiation, maturation, and morphology. RBCs play an important role development immune regulation. Notably, the novel scientific finding absorb fragments of tumor-carrying DNA overturns conventional wisdom do not contain nucleic acids. RBC...