Li Zhang

ORCID: 0009-0009-9234-2502
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About
Contact & Profiles
Research Areas
  • Metabolomics and Mass Spectrometry Studies
  • AI in cancer detection
  • Global Cancer Incidence and Screening
  • Cholinesterase and Neurodegenerative Diseases
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Phytochemicals and Antioxidant Activities
  • GABA and Rice Research
  • Carbon and Quantum Dots Applications
  • Microbial Natural Products and Biosynthesis
  • Plant Stress Responses and Tolerance
  • Pharmacogenetics and Drug Metabolism
  • Plant biochemistry and biosynthesis
  • Cancer therapeutics and mechanisms
  • Radiomics and Machine Learning in Medical Imaging

Shihezi University
2025

Sichuan Agricultural University
2023-2024

Sichuan Academy of Traditional Chinese Medicine
2023

Science and Technology Department of Sichuan Province
2023

The detailed metabolic map for camptothecin (CPT) biosynthesis in Camptotheca acuminata has been proposed according to our combined omics results. However, the CYP450-mediated epoxidation step CPT remains unexplored. A proteomics-guided approach was used identify and annotate proteins enriched during vigorous metabolism period mature C. seedlings. Comparative analyses revealed that flavonoid biosyntheses were stems all of samples except leaves, respectively. CYP71BE genes screened based on...

10.1021/acschembio.3c00222 article EN ACS Chemical Biology 2023-07-31

More than 90% of deaths due to breast cancer (BC) are metastasis-related complications, with invasive ductal carcinoma (IDC) the being most common pathologic type and highly susceptible metastasis distant organs. BC patients who develop metastases more likely have a poor prognosis quality life, so it is extremely important recognize diagnose whether occurred in IDC as early possible. In this study, we non-invasive classification system for detecting metastasis. We used Anaconda-Jupyter...

10.1371/journal.pone.0310410 article EN cc-by PLoS ONE 2025-02-26

Tetracycline pollution in soil irreversibly damages the biosafety of plants by inhibiting mitochondrial function. Some traditional Chinese medicine (TCM) plants, such as Salvia miltiorrhiza Bunge, have a strong tolerance to damage. We comprehensively compared doxycycline (DOX) tolerances two ecotypes S. Sichuan and Shandong provinces found that ecotype had lower yield reduction, more stable accumulation medicinal ingredients, higher integrity, robust antioxidant system. The synergetic...

10.1021/acs.est.3c02908 article EN Environmental Science & Technology 2023-06-21
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