Zekai Li

ORCID: 0009-0009-9668-8092
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About
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Research Areas
  • Advanced Photocatalysis Techniques
  • Nanoplatforms for cancer theranostics
  • Advanced Nanomaterials in Catalysis
  • CRISPR and Genetic Engineering
  • Advanced biosensing and bioanalysis techniques
  • Electrocatalysts for Energy Conversion
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Insect symbiosis and bacterial influences
  • Fuel Cells and Related Materials
  • Nanocluster Synthesis and Applications
  • DNA and Nucleic Acid Chemistry
  • Toxic Organic Pollutants Impact
  • RNA and protein synthesis mechanisms
  • CO2 Reduction Techniques and Catalysts
  • Decision-Making and Behavioral Economics
  • Advanced oxidation water treatment
  • Plant Virus Research Studies
  • Autophagy in Disease and Therapy
  • Surface Modification and Superhydrophobicity
  • Gas Sensing Nanomaterials and Sensors
  • Cytomegalovirus and herpesvirus research
  • Viral Infections and Immunology Research
  • Copper-based nanomaterials and applications
  • Insect-Plant Interactions and Control
  • Neurobiology and Insect Physiology Research

Jiangsu University
2022-2025

Fujian Normal University
2022-2025

Nanjing Agricultural University
2020-2025

Hohai University
2025

Hebei University
2020-2024

Northwest Normal University
2021-2024

Shanghai Jiao Tong University
2023-2024

Chongqing University
2022-2024

Beihang University
2024

Center for Life Sciences
2023

Nucleotide-binding, leucine-rich repeat receptors (NLRs) perceive pathogen effectors to trigger plant immunity. The direct recognition mechanism of by coiled-coil NLRs (CNLs) remains unclear. We demonstrate that the Triticum monococcum CNL Sr35 directly recognizes effector AvrSr35 from Puccinia graminis f. sp . tritici and report a cryo–electron microscopy structure resistosome crystal AvrSr35. show forms homodimers are disassociated into monomers upon domain Sr35, which induces assembly...

10.1126/sciadv.abq5108 article EN cc-by-nc Science Advances 2022-09-09

Abstract The emerging SARS-CoV-2 variants, commonly with many mutations in S1 subunit of spike (S) protein are weakening the efficacy current vaccines and antibody therapeutics. This calls for variant-proof targeting more conserved regions S protein. Here, we designed a recombinant vaccine, HR121, HR1 domain S2 HR121 consisting HR1–linker1–HR2–linker2–HR1, is conformationally functionally analogous to present fusion intermediate conformation subunit. Immunization rabbits rhesus macaques...

10.1038/s41422-022-00746-3 article EN cc-by Cell Research 2022-11-10

We review the design of MOFs as heterogeneous photocatalysts, analysing research on their use in water pollutant degradation, splitting and CO 2 reduction. Advantages disadvantages MOFs-based catalytic mechanisms future are evaluated.

10.1039/d3cy00479a article EN Catalysis Science & Technology 2023-01-01

Vision enables both image-forming perception, driven by a contrast-based pathway, and unconscious non-image-forming circadian photoentrainment, an irradiance-based pathway1,2. Although two distinct photoreceptor populations are specialized for each visual task3-6, photoreceptors can additionally contribute to photoentrainment of the clock in different species7-15. However, it is unknown how pathway functionally implement segregation irradiance signals required from contrast image perception....

10.1038/s41586-023-06681-6 article EN cc-by Nature 2023-10-25

Faced with the aggravation of environmental pollution and looming energy crisis, BiVO4, as an emerging promising photocatalyst, has drawn more attention researchers. Because its suitable band gap special electronic structure, BiVO4 shows excellent photocatalytic activity, which advantages low preparation cost, visible-light absorption, edge position. Herein, research status BiVO4-related catalysts used in photocatalysis was reviewed, including preparations using hydrothermal method,...

10.1021/acs.energyfuels.3c03932 article EN Energy & Fuels 2023-12-26

Abstract Teleost fish type I IFNs and the associated receptors from cytokine receptor family B (CRFB) are characterized by remarkable diversity complexity. How bind to their is still not fully understood. In this study, we demonstrate that CRFB1 CRFB5 constitute pair through which subgroup d IFN (IFNd) large yellow croaker, Larimichthys crocea, activates conserved JAK-STAT signaling pathway as a part of antiviral response. Our data suggest L. crocea IFNd (LcIFNd) has higher binding affinity...

10.4049/jimmunol.2300651 article EN The Journal of Immunology 2024-02-12

Due to its desirable optoelectronic properties, localized surface plasmon resonance (LSPR) can hopefully play a promising role in photocatalytic CO 2 reduction reaction (CO RR). In this review, mechanisms and applications of LSPR effect field are introduced detail.

10.1039/d2cy01967a article EN Catalysis Science & Technology 2023-01-01

Abstract Cas12h1 is a compact CRISPR-associated nuclease from functionally diverse type V CRISPR-Cas effectors and recognizes purine-rich protospacer adjacent motif (PAM) distinct that of other Cas effectors. Here, we report the nickase preference Cas12h1, which predominantly cleaves nontarget strand (NTS) double-stranded DNA (dsDNA) substrate. In addition, acts as in human cells. We further determined cryo-EM structures surveillance, R-loop formation, interference states, revealing...

10.1038/s41392-025-02147-5 article EN cc-by Signal Transduction and Targeted Therapy 2025-02-12
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