A5033355298- Ocular Surface and Contact Lens
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Ophthalmology and Visual Impairment Studies
- Corneal surgery and disorders
- Cerebral Venous Sinus Thrombosis
- Glaucoma and retinal disorders
- Congenital Diaphragmatic Hernia Studies
- Retinal Diseases and Treatments
- Congenital Anomalies and Fetal Surgery
- RNA Research and Splicing
- Extracellular vesicles in disease
- Maternal Mental Health During Pregnancy and Postpartum
- Axon Guidance and Neuronal Signaling
- Protein Degradation and Inhibitors
- Maternal and Perinatal Health Interventions
- Cancer, Hypoxia, and Metabolism
- Family Support in Illness
- Hernia repair and management
- Nuclear Receptors and Signaling
- RNA modifications and cancer
- Corrosion Behavior and Inhibition
- Epigenetics and DNA Methylation
- Angiogenesis and VEGF in Cancer
Albany Medical Center Hospital
2023
Cornell University
2018-2020
Florida State University
2018-2020
Nanchang University
2018-2019
Third Affiliated Hospital of Nanchang University
2018-2019
University of California, San Francisco
2018-2019
Third Hospital of Nanchang
2018
Long non-coding RNA (lncRNA) SNHG5 has been found to play an important role in tumors. Nevertheless, the function and mechanism of lncRNA osteosarcoma (OS) remains unclear. The purpose this study was investigate whether can regulate occurrence development OS cells. We performed quantitative real time PCR detect expression 143B, MG63 (knockdown) U2OS, U2R (overexpression) cell lines were chosen for SNHG5. effect SNHG5, miR-212-3p, SGK3 cells explored by MTT assays, clony formation, flow...
Précis: Micropulse cyclophotocoagulation (MPCP) lowered intraocular pressure (IOP) in the short-term but nearly half required additional intervention. Mydriasis was most common complication (11%); 15% lost ≥3 Snellen lines of acuity; 11% had persistent complications at last follow-up. Purpose: The purpose this study to evaluate efficacy and MPCP a large series patients with all stages glaucoma. Design: Multicenter, retrospective chart review from 3 clinical sites. Participants: One hundred...
Mortality factor 4‑like 1 (MORF4L1) is a member of subgroup histone acetyltransferases and belongs to the mortality on chromosome 4 (MORF4) class proteins. However, role MORF4L1 in cancers largely unknown. Using reverse transcription‑quantitative polymerase chain reaction published datasets, present study demonstrated that expression decreased several cancers, including nasopharyngeal carcinoma (NPC). Additionally, methylation rate promoter was identified be significantly higher tumour cells...
Abstract Retinoblastoma (RB) is the most common type of intraocular malignant tumor that occurs in childhood. AR‐42, a member newly discovered class phenylbutyrate‐derived histone deacetylase inhibitors, exerts antitumor effects on many cancers. In present study, we initially evaluated effect AR‐42 towards RB cells and explored underlying mechanism this disease. Our results found showed powerful at low micromolar concentrations by inhibiting cell viability, blocking cycle, stimulating...
To evaluate the influence of age and axial length (AL) on position fovea in patients with high myopia (HM).In this prospective study, 96 (186 eyes) HM were consecutively recruited from Third Affiliated Hospital Nanchang University. DRI-OCT Atlantis, fundus imaging, IOL Master used study. Three indices measured: distance between optic nerve head (ONH) center (DFO), vertical horizontal line pass ONH (VDFO), (HDFO). These measurements to analyze effects different groups (A1, A2, A3 groups) AL...
Background: miR-24-3p is a microRNA (miRNA) that involved in the differentiation of various types cancers and has been shown to act as an oncogene or tumor suppressor certain cancers. However, underlying mechanism miR-24-3p/TEL2 pathway not elucidated yet.Methods: The expression mRNA NP69 cells five NPC cell lines was detected. mimics were transfected into S26 6-10B explore effect on TEL2 protein levels by Western blotting. In addition, tissue collected from 116 patients with NPC, total RNA...
AIM: To evaluate the relationship between contrast sensitivity (CS) and corneal shape following overnight orthokeratology (OK). METHODS: We conducted a retrospective clinical study of 80 lens-wearing myopia patients, all whom had undergone OK been evaluated by Orbscan II topography. measured surface irregularity index (SIRI) topography at 3 5 mm, size flattened central curvature lens (zone A), cornea altered B), pupillary area level C), crossover zones A C AC), B (BC), ratio BC to (BC/B), AC...
Congenital diaphragmatic hernias (CDH) affect variable portions of diaphragm, resulting in herniation abdominal contents into the chest. CDH typically is diagnosed prenatally or presents soon after birth with respiratory distress and abnormal chest X-ray (CXR) findings. Presentation infancy rare but well described. We present a case delayed presentation right following left repair. An 18-month-old boy history repaired newborn period presented newly elevated hemidiaphragm presumed to be an...
Postnatal depression is a critical public health issue with substantial impact on child development outcomes and family functioning. With the additional stressors that arose during COVID-19 pandemic, global mental has been marked. This study aims to examine change in prevalence of postnatal (PND) Singaporean women before onset pandemic period. A single-center observational cross-sectional was conducted at Kandang Kerbau Women’s Children’s Hospital (KKH) where were screened for using...