A5101467273- Peripheral Neuropathies and Disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hereditary Neurological Disorders
- Gallbladder and Bile Duct Disorders
- Child Nutrition and Water Access
- Lung Cancer Diagnosis and Treatment
- Cancer-related Molecular Pathways
- Cardiac Imaging and Diagnostics
- Pancreatic and Hepatic Oncology Research
- Cardiovascular Health and Risk Factors
- Folate and B Vitamins Research
- Healthcare and Venom Research
- Breast Cancer Treatment Studies
- Medical Imaging and Pathology Studies
- Prostate Cancer Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Nerve injury and regeneration
- Urologic and reproductive health conditions
- Prostate Cancer Treatment and Research
- Global Public Health Policies and Epidemiology
- Autoimmune Neurological Disorders and Treatments
- Dielectric materials and actuators
- Paleopathology and ancient diseases
- Viral-associated cancers and disorders
- Chemical Safety and Risk Management
Anhui Medical University
2024
Xi’an Children’s Hospital
2024
The University of Texas Health Science Center at Houston
2024
Sichuan University
2024
Chengdu Sport University
2024
First Affiliated Hospital of Anhui Medical University
2024
Chengdu Medical College
2019-2023
Chengdu Women's and Children's Central Hospital
2019-2023
Jiaxing University
2023
First Hospital of Jiaxing
2023
Abstract Cohort purpose The China Multi-Ethnic (CMEC) is a community population-based prospective observational study aiming to address the urgent need for understanding NCD prevalence, risk factors and associated conditions in resource-constrained settings ethnic minorities China. Basics A total of 99 556 participants aged 30 79 years (Tibetan populations include those 18 years) from Tibetan, Yi, Miao, Bai, Bouyei, Dong groups Southwest were recruited between May 2018 September 2019....
Abstract Background Mediation analysis aims to determine how intermediate variables affect exposure disease. In this study, 25-hydroxyvitamin D (25(OH)D) was evaluated assess its role in mediating heavy metal and cardiovascular disease (CVD). Methods A total of 9,377 participants from the National Health Nutrition Examination Survey (NHANES) for years 2011-2018 were included. Firstly, restricted cubic spline (RCS), multivariable logistic regression model performed estimate association...
Chelerythrine chloride (CHE) is a benzodiazepine alkaloid derived from natural herbs with significant anti-tumor and anti-inflammatory activities. However, the exact role underlying mechanisms of CHE in colorectal cancer (CRC) remain unclear. Therefore, this study aimed to investigate influence on progression CRC. Cell Counting Kit-8 assay (CCK-8), transwell, apoptosis rate, cell cycle distribution, reactive oxygen species (ROS), colony formation determined anti-proliferative activity CRC...
The Optical Surface Management System (OSMS) is a simple, fast, reproducible, and accurate solution for patient set-up can minimize random day-to-day errors. However, studies in breast cancer patients are rare.To analyze 200 set-ups 20 with by comparing the OSMS conventional cone-beam computed tomography (CBCT).Displacements from concurrent CBCT registrations were compared total of setups to interfractional displacement positioning three dimensions (lateral, longitudinal, vertical...
Introduction Many researchers used machine learning (ML) to predict the prognosis of breast cancer (BC) patients and noticed that ML model had good individualized prediction performance. Objective The cohort study was intended establish a reliable data analysis by comparing performance 10 common algorithms traditional American Joint Committee on Cancer (AJCC) stage, this in Web application development provide for others. Methods This included 63145 BC from Surveillance, Epidemiology, End...
Abstract Cohort purpose The China Multi-Ethnic (CMEC) is a community population-based prospective observational study aiming to address the urgent need for understanding NCD prevalence, risk factors and associated conditions in resource-constrained settings ethnic minorities China. Basics A total of 99 556 participants aged 30 79 years (Tibetan populations include those 18 years) from Tibetan, Yi, Miao, Bai, Bouyei, Dong groups Southwest were recruited between May 2018 September 2019....
Anti-glycan antibodies directed against gangliosides are now considered the major immune effectors that induce damage to intact nerve fibers in some variants of monophasic neuropathic disorders comprise Guillain-Barré syndrome. Recent experimental studies elucidating complexity anti-glycan antibody-mediated pathobiologic effects on and injured nerves undergoing repair discussed.
There is no available targeted therapy or imaging agent for triple negative breast cancer (TNBC). We developed a small-sized dendrimer-based nanoparticle containing clinical relevant MRI contrast agent, GdDOTA and NIR fluorescent dye, DL680. Systemic delivery of dual-modal nanoparticles led to accumulation the agents in flank mouse model TNBC that were detected by both optical MR imaging. In-vivo fluorescence images, as well ex-vivo images individual organs, demonstrated accumulated into...
Abstract Maternal periconceptional folic acid supplementation (FAS) has been documented to be associated with decreased risk of nonsyndromic oral clefts (NsOC). However, the results remain inconclusive. In this population-based case–control study 807 singletons affected by NsOC and 8070 healthy neonates who were born between October 2010 September 2015 in Chengdu, China, we examined association maternal FAS cleft lip or without palate (NsCL/P), (NsCP). Unconditional logistic regression...
The American Joint Committee on Cancer (AJCC) recommended retrieval of at least 12 lymph nodes and firstly classified N category by the number positive (PLNs) for Distal Cholangiocarcinoma (DCC).The end this cohort study was to explore optimal cut-off values examined (ELNs) PLNs better stratify patients utilizing a population-based database.A 758 with DCC from Surveillance, Epidemiology, End Results (SEER) database were enrolled in comparing survival analysis.Survival analysis found that...
Human drug metabolites (HDMs) are important chemicals widely used in drug-related studies. However, acquiring these enzyme-derived and regio-/stereo-selectively modified compounds through chemical approaches is complicated. PikC a biosynthetic P450 enzyme involved pikromycin biosynthesis from the bacterium Streptomyces venezuelae. Here, we identify mutant PikCD50N as potential biocatalyst, with broad substrate scope, diversified product profile, high catalytic efficiency, for preparation of...
Introduction The current study focuses on understanding the functional role of different subsets endoneurial macrophages in autoimmune polyneuropathies (AP) and traumatic peripheral nerve injury (TPNI), which holds potential for clinical application. Recent studies have advanced our diverse origins within nerves. However, there remains a gap knowledge regarding how from affect disease progression AP versus TPNI. Methods Flow cytometry was utilized to analyze macrophage phenotypes, including...
To summarise the process of conversion epidural labour analgesia to anaesthesia for caesarean delivery and explore relationship between duration conversion.Parturients who underwent from May 2019 April 2020 at Chengdu Women's Children's Central Hospital, Sichuan Maternal Child Health Jinjiang District Hospital were selected. If position catheter was correct effect good, patients converted surgical anaesthesia. ineffective, spinal (SA) administered immediately. For category-1 emergency...