A5048086390- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Mesenchymal stem cell research
- Biosensors and Analytical Detection
- SARS-CoV-2 detection and testing
- Advanced biosensing and bioanalysis techniques
- Molecular Biology Techniques and Applications
- Exercise and Physiological Responses
- Regional Development and Environment
- Neurological Disease Mechanisms and Treatments
- Computational Drug Discovery Methods
- Congenital Heart Disease Studies
- Medical Research and Treatments
- Cardiac and Coronary Surgery Techniques
- Advanced Biosensing Techniques and Applications
- RNA Interference and Gene Delivery
- Drug-Induced Hepatotoxicity and Protection
- Metabolism, Diabetes, and Cancer
- Tracheal and airway disorders
- Acupuncture Treatment Research Studies
- Neurogenesis and neuroplasticity mechanisms
- Immune Cell Function and Interaction
- Pharmacological Effects of Natural Compounds
- Cardiac Structural Anomalies and Repair
China Southern Power Grid (China)
2023
University of Oxford
2009-2020
NIHR Bristol Cardiovascular Biomedical Research Unit
2015-2019
University of Bristol
2015-2019
Science Oxford
2018
Cardiff Metropolitan University
2008
Summary The pandemic coronavirus SARS‐CoV‐2 in the world has caused a large infected population suffering from COVID‐19. To curb spreading of virus, WHO urgently demanded an extension screening and testing; thus, rapid simple diagnostic method is needed. We applied reverse transcription‐loop‐mediated isothermal amplification (RT‐LAMP) to achieve detection 30 min. designed four sets LAMP primers (6 each set), targeting viral RNA regions orf1ab, S gene N gene. A colorimetric change was used...
Background Living grafts produced by combining autologous heart‐resident stem/progenitor cells and tissue engineering could provide a new therapeutic option for definitive correction of congenital heart disease. The aim the study was to investigate antigenic profile, expansion/differentiation capacity, paracrine activity, pro‐angiogenic potential cardiac pericytes assess their engrafting capacity in clinically certified prosthetic grafts. Methods Results CD 34 pos cells, negative endothelial...
Abstract We present an example of applying ‘need-driven’ product design principle to the development a rapid test kit detect SARS-COV-2 (COVID-19). The tests are intended for use in field and, longer term, home use. They whether subject is currently infected with virus and infectious. urgent need large numbers setting imposes constraints such as short time lack access specialist equipment, laboratories skilled technicians perform interpret results. To meet these needs, antigen based on...
The materials available for the right ventricular outflow tract (RVOT) reconstruction in patients with tetralogy of fallot (TOF)/pulmonary atresia come severe limitation long-term degeneration and lack growth potential, causing dysfunction, aneurysm formation, arrhythmias, thus necessitating several high-risk reoperations throughout patients' lives. In this study, we evaluated capacity mesenchymal stem cells (MSCs) derived from Wharton's Jelly (WJ-MSCs), gelatinous inner portion umbilical...
There is much evidence that prolonged intense exercise suppresses the immune system. However, intracellular biochemical mechanisms linking and immunosuppression remain obscure. The purpose of this study was to investigate hypothesis exercise-induced inactivation 5′AMP-activated protein kinase (AMPK) disrupts individual cell function, thus may be linked immunosuppression. To confirm AMPK’s role in cells, AMPK activity assessed cultured monocytic Mono Mac 6 (MM6) cells. effects single bouts...
Human Multipotent Stromal Cells (MSCs) are a valuable resource for regenerative medicine and widely studied. They can be isolated from variety of tissues differentiate into multiple cell types (multi-potent). Many reports have been published using human MSCs to able compare outcome, or identify differences between MSCs, several surface markers proposed. Nevertheless, still many remain. Gene expression is known different stage origin. Furthermore, cells cultured on culture dish (2D) show gene...
Many children with congenital heart disease need prosthetic replacement grafts in the form of new valves, conduits and patches. Owing to lack growth potential currently available grafts, a child born defects may typically undergo major cardiac surgery several times throughout their lifetime. A very promising approach solve this problem be use tissue engineering, which stem cells are seeded living-tissue products that have structural functional properties can used restore, maintain or improve...
To solve the main problems faced by medium voltage distribution network in urban core areas of China, this paper first analyzed advantages and disadvantages typical high reliability connection modes at home abroad, compared their differences power supply reliability, economy, difficulty transformation implementation, as well applicability China. Then, concept "star type" was proposed, it's structure, configuration principles, characteristics were elaborated detail. Finally, taking a grid...