Elliott J. Wright

ORCID: 0000-0001-5427-155X
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Research Areas
  • Marine Toxins and Detection Methods
  • Nicotinic Acetylcholine Receptors Study
  • Marine and coastal ecosystems
  • Environmental Toxicology and Ecotoxicology
  • Animal Ecology and Behavior Studies
  • Analytical chemistry methods development
  • Forensic Toxicology and Drug Analysis
  • Marine Sponges and Natural Products
  • Analytical Chemistry and Chromatography
  • Aquatic Ecosystems and Phytoplankton Dynamics
  • Environmental Chemistry and Analysis
  • Hemoglobin structure and function
  • Advanced Chemical Sensor Technologies
  • Water Quality Monitoring and Analysis
  • Mass Spectrometry Techniques and Applications
  • Analytical Methods in Pharmaceuticals
  • Marine Biology and Environmental Chemistry
  • Isotope Analysis in Ecology
  • Nitric Oxide and Endothelin Effects
  • Marine Invertebrate Physiology and Ecology
  • Pesticide Residue Analysis and Safety
  • Chemical synthesis and alkaloids
  • Molecular Sensors and Ion Detection
  • Aquaculture disease management and microbiota
  • Metabolomics and Mass Spectrometry Studies

National Research Council Canada
2014-2024

Dalhousie University
2014

Institute for Marine Biosciences
2011

LC/MS methodology for the analysis of domoic acid and lipophilic toxins in shellfish was developed using a hybrid triple quadrupole linear ion trap mass spectrometer. For routine quantitation scheduled selected reaction monitoring (SRM) method acid, okadaic dinophysistoxins, azaspiracids, pectenotoxins, yessotoxins, gymnodimines, spirolides, pinnatoxins validated. The performed well terms LOD, linearity, precision, trueness. Taking advantage high instrument sensitivity, matrix effects were...

10.5740/jaoacint.sgemccarron article EN Journal of AOAC International 2014-03-01
Gustavo Martos Steven Westwood Magali Bedu Tiphaine Choteau R D Josephs and 95 more Robert Wielgosz Mine Bílsel G. Aktaş Hatice Altuntas Gonca Coşkun Tugba Dıspınar Gezer Simay Gündüz Alper İşleyen Sukran Akkus Ozen İlker Ün Hasibe Yılmaz Stephen Davies Mahiuddin Alamgir Benjamin Chan Michael Moawad Emma Kent Christophe Nguyen Eliane Cristina Pires do Rego Bruno Carius Garrido Jane Luiza Nogueira Fernandes Wagner Wollinger Thiago de Oliveira Araújo Ana Catalina Osorio Marcelo Dominguez de Almeida Marie-Pier Thibeault Isabelle Rajotte Jennifer Bates Sabrina D. Giddings Elliott J. Wright Krista Thomas Pearse McCarron Andreas Brinkmann Fuhai Su Qinghe Zhang Qi Wei Wei Zhang Lianhua Shi Weihua Wang Ting Huang Yaxin Han Wenxin Li Janice E. Lau C.-K. Tse W H Fung Klas Meyer Panagiota Giannikopoulou Ilias Kakoulidis Yoshitaka Shimizu Migaku Kawaguchi Sakae Eyama Toshihiro Suzuki Yoshiyasu Yamauchi Taichi Yamazaki Satoe Nakamura Xinnu Bao Yuko Kitamaki Megumi Kato Nobuyasu Itoh A. I. Krylov Ludmila V Eliseeva Anna Yu Ivanova E. M. Lopushanskaya A. Yu. Mikheeva Марина Всеволодовна Палагина С. В. Харитонов Teo Tang Lin Cheow Pui Sze Ting Lu Mei Guo Juan Wang Benny Meng Kiat Tong Sim Lay Peng Leung Ho Wah R.Y.C. Shin Désirée Prevoo-Franzsen Nontete Nhlapo Caitlin Swiegelaar Maria Fernandes-Whaley Thabang Chiloane Laura Quinn Mare Linsky Dominique Marajh Sunyoung Lee Song‐Yee Baek Ha‐Jeong Kwon Jae‐Hyun Lee Kihwan Choi Sornkrit Marbumrung Ponhatai Kankaew Pornnipa Jongmesuk Cheerapa Boonyakong Patumporn Rodruangtham Nittaya Sudsiri Chomchai Suksai Sarayut Watchasit

Main text The CCQM-K148.b comparison, undertaken with a parallel pilot study CCQM-P187.b, was coordinated by the BIPM and UME on behalf of Consultative Committee for Amount Substance: Metrology in Chemistry Biology (CCQM) Working Group Organic Analysis (OAWG). It National Measurement Institutes (NMIs) Designated (DIs) which provide measurement services organic analysis under CIPM Mutual Recognition Arrangement (MRA) designated Track A comparison within OAWG implementation CCQM Strategy...

10.1088/0026-1394/62/1a/08012 article EN Metrologia 2025-01-01

The goal of this research was to develop a robust method for taste and odour compounds that can be implemented by laboratories with mass spectrometers lacking chemical ionisation capabilities or specialised sample introduction hardware are commonly used methods. Development, optimisation, validation solid-phase extraction using liquid injection gas chromatography – tandem spectrometry detection electron impact described. Camphor as an internal standard, through development robustness testing...

10.1080/03067319.2014.974586 article EN International Journal of Environmental & Analytical Chemistry 2014-10-21

Paralytic shellfish toxins (PSTs) are a complex class of analogs the potent neurotoxin saxitoxin (STX). Since calibration standards not available for many PSTs, including C-11 hydroxyl called M-toxins, accurate quantitation by liquid chromatography–mass spectrometry (LC-MS) can be challenging. In absence standards, PSTs often semiquantitated using different analog (e.g., STX), an approach with high degree uncertainty due to highly variable sensitivity between analytes in electrospray...

10.3390/toxins12060398 article EN cc-by Toxins 2020-06-16

Okadaic acid (OA) group toxins may accumulate in shellfish and can result diarrhetic poisoning when consumed by humans, are therefore regulated. Purified required for the production of certified reference materials used to accurately quantitate toxin levels water samples, other research purposes. An improved procedure was developed isolation dinophysistoxin 2 (DTX2) from (M. edulis), reducing number purification steps eight five, thereby increasing recoveries ~68%, compared ~40% a previously...

10.3390/md18120647 article EN cc-by Marine Drugs 2020-12-16

The presence of azaspiracids (AZAs) in shellfish may cause food poisoning humans. AZAs can accumulate filtering seawater that contains marine dinoflagellates such as Azadinium and Amphidoma spp. More than 60 AZA analogues have been identified, which AZA1, AZA2 AZA3 are regulated Europe. Shellfish matrices complicate quantitation by ELISA LC–MS methods. Polyclonal antibodies developed bind specifically to the C-26–C-40 domain structure could potentially be used for selectively extracting...

10.1016/j.jchromb.2022.123360 article EN cc-by Journal of Chromatography B 2022-07-07

Azaspiracids (AZAs) are a group of biotoxins produced by the marine dinoflagellates Azadinium and Amphidoma spp. that can accumulate in shellfish cause food poisoning humans. Of 60 AZAs identified, levels AZA1, AZA2, AZA3 regulated as safety measure based on occurrence toxicity. Information about metabolism is limited. Therefore, fraction blue mussel hepatopancreas was made to study AZA1–3 vitro. A range AZA metabolites were detected liquid chromatography–high-resolution tandem mass...

10.1021/acs.jafc.1c03831 article EN Journal of Agricultural and Food Chemistry 2021-09-17

Microcystins (MCs) are a potent class of hepatotoxins produced by several species cyanobacteria, which have been responsible for illness and death in livestock humans.

10.1039/c8ay00516h article EN Analytical Methods 2018-01-01

Liquid chromatography–high-resolution mass spectrometry (LC-HRMS) analysis of a Namibian strain Gonyaulax spinifera showed the presence number yessotoxins (YTXs). Principal among these were YTX (1), homoYTX (2), and tentative hydroxylated analogue that did not correspond to any previously confirmed structures. Culturing G. afforded sufficient biomass for purification new through series solvent partitioning chromatographic steps, yielding ∼0.9 mg as solid. NMR spectroscopy, ion-trap...

10.1021/acs.jnatprod.9b00318 article EN Journal of Natural Products 2019-07-08

Two high-mass polar compounds were observed in aqueous side-fractions from the purification of okadaic acid (1) and dinophysistoxin-2 (2) Dinophysis blooms Spain Norway. These isolated shown to be 24-O-β-d-glucosides 1 2 (4 5, respectively) by nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry, enzymatic hydrolysis. These, together with standards 1, 2, dinophysistoxin-1 (3), a synthetic specimen 7-deoxy-1 (7), combined an understanding their spectrometric fragmentation...

10.3390/toxins13080510 article EN cc-by Toxins 2021-07-21

Azaspiracids (AZAs) are a group of polyether marine algal toxins known to accumulate in shellfish, posing risk human health and the seafood industry. Analysis AZAs is typically performed using LC-MS, which can suffer from matrix effects that significantly impact accuracy measurement results. While use isotopic internal standards an effective approach correct for these effects, isotopically labelled not currently available. In this study, 18O-labelled AZA1, AZA2, AZA3 were prepared by...

10.1007/s00216-023-04868-4 article EN cc-by Analytical and Bioanalytical Chemistry 2023-08-02

The presence of azaspiracids (AZAs) in shellfish may cause food poisoning humans. AZAs can accumulate filtering seawater that contains marine dinoflagellates such as Azadinium and Amphidoma spp. More than 60 AZA analogues have been identified, which AZA1, AZA2 AZA3 are regulated Europe. Shellfish matrices complicate quantitation by ELISA LC–MS methods. Polyclonal antibodies developed bind specifically to the C-26–C-40 domain structure could potentially be used for selectively extracting...

10.2139/ssrn.4076676 article EN SSRN Electronic Journal 2022-01-01
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