Simay Gündüz
A5014467708- Molecular Sensors and Ion Detection
- Analytical Chemistry and Chromatography
- Pesticide Residue Analysis and Safety
- Luminescence and Fluorescent Materials
- Sulfur Compounds in Biology
- Electrochemical Analysis and Applications
- Chemical Thermodynamics and Molecular Structure
- Analytical chemistry methods development
- Muscle metabolism and nutrition
- Analytical Methods in Pharmaceuticals
- Metabolomics and Mass Spectrometry Studies
- Advanced Chemical Sensor Technologies
- Analytical Chemistry and Sensors
- Synthesis of Organic Compounds
- Halal products and consumer behavior
- Advanced biosensing and bioanalysis techniques
- Electrochemical sensors and biosensors
- Identification and Quantification in Food
- Pharmacological Effects and Assays
- Food Safety and Hygiene
- Scientific Measurement and Uncertainty Evaluation
- Free Radicals and Antioxidants
- Cytokine Signaling Pathways and Interactions
- Cassava research and cyanide
- Inorganic and Organometallic Chemistry
Tübitak National Metrology Institute
2012-2023
Istanbul Technical University
2012-2023
Scientific and Technological Research Council of Turkey
2015-2022
Laboratoire de Chimie
2018
National Institute of Metrology
2018
Gebze Technical University
2018
Harran University
2016
Fatih University
2012
Hypochlorite/hypochlorous acid (ClO-/HOCl), among the diverse reactive oxygen species, plays a vital role in various biological processes. Besides, ClO- is widely known as sanitizer for fruits, vegetables, and fresh-cut produce, killing bacteria pathogens. However, excessive level of can lead to oxidation biomolecules such DNA, RNA, proteins, threatening organs. Therefore, reliable effective methods are utmost importance monitor trace amounts ClO-. In this work, novel BODIPY-based...
Modification of the present synthetic methods led to syntheses 3-hydroxyflavones in a shorter reaction time, with simple purification and higher yields. Application method provided 3HFs having hydroxyl group on phenyl ring (ring B) one step, which is an improvement compared four steps, long low yield using current available literature.
Main text Inherited metabolic disorders affect approximately 1 in 1000 babies; amino acid are less frequent, at 6000. Babies diagnosed with require constant monitoring of blood concentration, especially for disease states such as phenylketonuria. In addition, measurement may aid the evaluation several other neurological and nutritional disorders. Free acids healthy patients typically low mg/kg range but, example, elevated phenylalanine indicates phenylketonuria state. Evidence successful...
Main text The CCQM-K148.b comparison, undertaken with a parallel pilot study CCQM-P187.b, was coordinated by the BIPM and UME on behalf of Consultative Committee for Amount Substance: Metrology in Chemistry Biology (CCQM) Working Group Organic Analysis (OAWG). It National Measurement Institutes (NMIs) Designated (DIs) which provide measurement services organic analysis under CIPM Mutual Recognition Arrangement (MRA) designated Track A comparison within OAWG implementation CCQM Strategy...
Main text The CCQM-K179 comparison, undertaken with a parallel pilot study CCQM-P224, was coordinated by the BIPM and UME on behalf of Consultative Committee for Amount Substance: Metrology in Chemistry Biology (CCQM) Working Group Organic Analysis (OAWG). It National Measurement Institutes (NMIs) Designated (DIs) which provide measurement services organic analysis under CIPM Mutual Recognition Arrangement (MRA) designated Track C comparison within OAWG implementation CCQM Strategy Programme...
Under the auspices of Organic Analysis Working Group (OAWG) Comité Consultatif pour la Quantité de Matière (CCQM) a key comparison, CCQM K55.c, was coordinated by Bureau International des Poids et Mesures (BIPM) in 2012. Twenty National Measurement Institutes or Designated and BIPM participated. Participants were required to assign mass fraction valine present as main component comparison sample for CCQM-K55.c. The samples prepared from analytical grade L-valine purchased commercial supplier...
Main text The CCQM-K148.a comparison was coordinated by the BIPM on behalf of CCQM Organic Analysis Working Group for NMIs and DIs which provide measurement services in organic analysis under CIPM MRA. It undertaken as a "Track A" within OAWG strategic plan. demonstrates capabilities assigning mass fraction content solid compound having moderate molecular complexity, where has molar range (75 - 500) g/mol is non-polar (pK ow < −2), when present primary component neat material excess 950...
The comparison required the assignment of mass fraction folic acid present as main component in sample. Performance is representative a laboratory's measurement capability for purity organic compounds medium structural complexity [molecular weight range 300–500] and high polarity ( pK OW < −2). Methods used by eighteen participating NMIs or DIs were based on balance (summation impurities) qNMR approach, combination data obtained using both methods. results tended to give slightly lower...
Current methods for the analysis of fatty acid methyl esters (FAMEs) in rapeseed oil-based biodiesel refer to operationally defined measurands, which is a practical solution routine analysis. In this paper, new method SI-traceable quantification selected FAMEs and its validation are described. This has potential be reference applications requiring structurally measurands traceability SI as it allows direct comparisons well-characterised calibrants through use isotopically labelled analogues...
The supplementary comparison APMP.QM-S8: determination of mass fraction benzoic acid, methyl paraben and n-butyl in soy sauce was coordinated by the Health Sciences Authority, Singapore under auspices Organic Analysis Working Group (OAWG) Comité Consultatif pour la Quantité de Matière (CCQM). Ten national metrology institutes (NMIs) or designated (DIs) participated comparison. All for while six NMIs/DIs paraben. designed to enable participating demonstrate their measurement capabilities...
In this study, we provide a method using fluorescently labeled oligonucleotides for the diagnosis of microorganisms producing nucleases in real time, while growing them culture media. The detection such was possible short period as 10 minutes up to maximum 8 hours, depending on bacterial density. We also showed suitability new determination minimum inhibitory concentration (MIC) media very compared conventional methods. believe that it can make significant contribution gain insights analysis...
The CCQM-K78.a comparison was coordinated by the BIPM on behalf of CCQM Organic Analysis Working Group for NMIs and DIs which provide measurement services in organic analysis under CIPM MRA. key forms part OAWG 10-year strategic plan comparisons. underpins demonstration capabilities value assignment high polarity calibration solutions. model system selected amino acids aqueous solution. Participants were required to assign mass fractions, expressed μg/g, phenylalanine (Phe), leucine (Leu),...
A novel rhodamine based optical and electrochemical active probe, integrated with triphenylamine thiophene moiety, exhibited highly selective detection of Au(III) ions compared to the other metal species, such as Ag+, K+, Li+, Na+, Hg2+, Ba2+, Ca2+, Cd2+, Cu2+, Co2+, Mg2+, Mn2+, Ni2+, Pb2+, Zn2+ Pd2+, Al3+, Ce3+, Cr3+, Fe3+ Cr6+. Exploiting hydrolysis ring-opening reaction, probe offers privileged properties naked-eye (colorimetric), both “turn-on” “turn-off” fluorescence responses,...
The CCQM Organic Analysis Working Group (OAWG) agreed on a Track A comparison for the measurement of polar organic in biological matrix as part its 10-year strategic plan. As model this comparison, two clinical biomarkers: urea and uric acid, human serum were chosen. This was designed to enable participating National Metrology Institutes (NMIs) or Designated (DIs) demonstrate their capabilities determination analytes with molecular mass 50 500 g/mol, having polarity pK OW > 2 range 10...
Under the Comité Consultatif pour la Quantité de Matière (CCQM), a key comparison, CCQM-K104, was coordinated by National Institute of Metrology (NIM). The comparison designed to demonstrate laboratory's performance in determining mass fraction main component complex high purity organic material. Nine NMIs or DIs participated comparison. Eight participants reported their results. An additional impurity resolved from avermectin B 1 peak and tentatively identified as an unknown NMIA (National...