A5040236445- NMR spectroscopy and applications
- Advanced NMR Techniques and Applications
- Analytical Chemistry and Chromatography
- Advanced MRI Techniques and Applications
- Spectroscopy and Chemometric Analyses
- Microfluidic and Capillary Electrophoresis Applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Nuclear Physics and Applications
- Fault Detection and Control Systems
- Solar-Powered Water Purification Methods
- X-ray Diffraction in Crystallography
- Advanced Chemical Sensor Technologies
- Analytical chemistry methods development
- Crystallization and Solubility Studies
- Hydrocarbon exploration and reservoir analysis
- Mass Spectrometry Techniques and Applications
- Groundwater flow and contamination studies
- Various Chemistry Research Topics
- Metabolomics and Mass Spectrometry Studies
- Nuclear reactor physics and engineering
- Pesticide Residue Analysis and Safety
- Phase Equilibria and Thermodynamics
- Microplastics and Plastic Pollution
- Semiconductor Quantum Structures and Devices
- Advanced Control Systems Optimization
Federal Institute For Materials Research and Testing
2016-2025
Helmholtz Association of German Research Centres
2024
Humboldt-Universität zu Berlin
2013
Equinor (Norway)
2010
University of Münster
1992-2008
University of Cape Town
2004
General Mills (United States)
1997
Universität Hamburg
1994-1996
Los Alamos National Laboratory
1983-1985
International University Institute
1985
Plastic pollution is the biggest environmental concern of our time. Breakdown products like micro- and nano-plastics inevitably enter food chain pose unprecedented health risks. In this scenario, bio-based biodegradable plastic alternatives have been given a momentum aiming to bridge transition towards more sustainable future. Polyhydroxyalkanoates (PHAs) are one few thermoplastic polymers synthesized 100 % via biotechnological routes which fully biodegrade in common natural environments....
Mucus is a complex hydrogel that acts as defensive and protective barrier in various parts of the human body. The rise level viral infections has underscored importance advancing research into mucus-mimicking hydrogels for efficient design antiviral agents. Herein, we demonstrate gram-scale synthesis biocompatible, lignin-based virus-binding inhibitors reduce waste ensure long-term availability. are equipped with sulfate moieties, which known binding partners many viruses, including...
Modular plants using intensified continuous processes represent an appealing concept for the production of pharmaceuticals. It can improve quality, safety, sustainability, and profitability compared to batch processes; besides, it enables plug-and-produce reconfiguration fast product changes. To facilitate this flexibility by real-time quality control, we developed a solution that be adapted quickly new is based on compact nuclear magnetic resonance (NMR) spectrometer. The NMR sensor...
Abstract Near-infrared (NIR) spectroscopy is a promising candidate for low-cost, nondestructive, and high-throughput mass quantification of microplastics in environmental samples. Widespread application the technique currently hampered mainly by low sensitivity NIR compared to thermoanalytical approaches commonly used this type analysis. This study shows how can be extended smaller analyte levels combining it with simple rapid microplastic enrichment protocol. For purpose, widely flotation...
Ratiometric green-red fluorescent nanosensors for fluorometrically monitoring pH in the acidic range were designed from 80 nm-sized polystyrene (PS) and silica (SiO2) nanoparticles (NPs), red emissive reference dyes, a green naphthalimide probe, analytically spectroscopically characterized, compared regarding their sensing performance aqueous dispersion cellular uptake studies. Preparation of these optical probes, which are excitable by 405 nm laser or LED light sources, involved...
A big problem with the chemistry literature is that it not standardized respect to precise operational parameters, and real time corrections are hard make without expert knowledge. This lack of context means difficult reproducibility because many steps ambiguous, hence depend on tacit Here we present integration online NMR into an automated chemical synthesis machine (CSM aka. "Chemputer" which capable small-molecule using a universal programming language) allow analysis adjustment reactions...
Abstract Online NMR spectroscopy is an excellent tool to study complex reacting multicomponent mixtures and gain process insight understanding. For online studies under conditions, flow probes can be used in a wide range of temperature pressure. This paper compiles the most important aspects towards quantitative provides examples. After introduced as method for technical samples without sample preparation deuterated solvents, influences residence time distribution, pre‐magnetization, cell...
Medium-resolution nuclear magnetic resonance spectroscopy (MR-NMR) currently develops to an important analytical tool for both quality control and process monitoring. In contrast high-resolution online NMR (HR-NMR), MR-NMR can be operated under rough environmental conditions. A continuous re-circulating stream of reaction mixture from the vessel spectrometer enables a non-invasive, volume integrating analysis reactants products. Here, we investigate esterification 2,2,2-trifluoroethanol with...
NMR is a powerful analytical technique that combines an exquisite qualitative power, related to the unicity of spectra each molecule in mixture, with intrinsic quantitativeness, fact integral peak only depends on number nuclei (i.e., amount substance times equivalent signal), regardless molecule. Signal integration most common approach quantitative but has several drawbacks (vide infra). An alternative use hard modeling peaks. In this paper, we present pyIHM, Python package for...
Main text The CCQM-K148.b comparison, undertaken with a parallel pilot study CCQM-P187.b, was coordinated by the BIPM and UME on behalf of Consultative Committee for Amount Substance: Metrology in Chemistry Biology (CCQM) Working Group Organic Analysis (OAWG). It National Measurement Institutes (NMIs) Designated (DIs) which provide measurement services organic analysis under CIPM Mutual Recognition Arrangement (MRA) designated Track A comparison within OAWG implementation CCQM Strategy...
Abstract Porous and finely divided solids are distinguished by a large surface to volume ratio. As result, they have specific properties, such as enhanced reactivity, high adsorption capacity, lowered sinter temperature. This contribution gives survey over selected aspects of porous solids, with the main emphasis on methods characterization their applications. We treat regular pore network (zeolites) irregular structure (sintered compacts, rocks). After short review possibilities...
The measiireinent o f cholestcryl esters in human monocyte-derived macrophages using previously described high performance liquid chromatography methods is hampered bv the presence these cells of large amounts triglycerides.We present a simple reversed phase protocol for quantification cholesterol and cholestrryl monocyte/macrophages or other triglyceride-rich cells.Our method requires only lipid extraction mid hydrolvsis triglycerides sohition ethanolic potassium hydroxide sufficient...
Abstract Simple mixing or shaking of alkaline earth hydroxides with ammonium fluoride results in nanocrystalline phase pure metal fluorides M F 2 ( : Ca, Sr, Ba). The formation the was investigated by varying reaction conditions. Evidence found that just contact between starting materials is sufficient for to take place. X‐ray diffraction, elemental analysis, 19 MAS NMR spectroscopy, and measurements DC conductivities were used characterize regarding properties like crystal structure,...
Hydrolysis of protein samples into amino acids facilitates the use NMR spectroscopy for and peptide quantification. Different conditions have been tested quantifying aromatic proteins. The pH-dependent signal shifts in region acid were examined. A pH 12 was found to minimize overlap four acids. Several compounds, such as terephthalic acid, sulfoisophthalic benzene tricarboxylic applied internal standards. quantification from an standard performed. Using first two suggested standards,...
Mucus is a complex hydrogel acting as defensive and protective barrier in various parts of the human body. The structure composition mucus play an important role maintaining properties by filter for diffusion biomolecules pathogens. rise viral infections has underscored importance advancing research into mucus-mimicking hydrogels efficient design antiviral agents. However, performance strategy should not only be assessed based on its efficacy inhibiting but also sustainability. Herein, we...
Mechanochemistry is an environmentally friendly synthetic approach enabling the sustainable production of a wide range chemicals while reducing or eliminating need for solvents. Reactive extrusion aims to move mechanochemistry from its conventional gram-scale batch reactions, typically performed in laboratory ball mills, continuous large-scale process. Meeting this challenge requires situ monitoring techniques gain insights into reactive and underlying processes. While effectiveness Raman...