Baoyu Li

ORCID: 0000-0001-5499-9700
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Research Areas
  • Animal Virus Infections Studies
  • Covalent Organic Framework Applications
  • Synthesis and biological activity
  • Viral gastroenteritis research and epidemiology
  • Graphene and Nanomaterials Applications
  • Radioactive element chemistry and processing
  • Metal-Organic Frameworks: Synthesis and Applications
  • Virus-based gene therapy research
  • Graphene research and applications
  • Fungal Plant Pathogen Control
  • Viral Infections and Immunology Research
  • Luminescence and Fluorescent Materials
  • Synthesis of Organic Compounds
  • Viral Infectious Diseases and Gene Expression in Insects
  • Click Chemistry and Applications
  • Synthesis and Characterization of Heterocyclic Compounds
  • Multicomponent Synthesis of Heterocycles
  • Thin-Film Transistor Technologies
  • Cancer Research and Treatments
  • Organic Light-Emitting Diodes Research
  • Inertial Sensor and Navigation
  • Advanced biosensing and bioanalysis techniques
  • Animal Disease Management and Epidemiology
  • RNA modifications and cancer
  • Plant-Microbe Interactions and Immunity

Soochow University
2016-2025

Lanzhou Veterinary Research Institute
2011-2025

Chinese Academy of Agricultural Sciences
2009-2025

Lanzhou University
2023-2025

Xi'an Jiaotong University
2023-2025

Zhejiang A & F University
2025

Gansu University of Traditional Chinese Medicine
2025

Guangxi University
2021-2024

China Academy of Launch Vehicle Technology
2016-2024

Inner Mongolia University of Technology
2024

Direct removal of 99TcO4– from alkaline nuclear waste is desirable because the management and environmental protection relevant to energy but yet be achieved given that combined features decent base-resistance high uptake selectivity toward anions with low charge density have not been integrated into a single anion-exchange material. Herein, we proposed strategy overcoming these challenges by rationally modifying imidazolium unit cationic polymeric network (SCU-CPN-4) bulky alkyl groups...

10.1021/acscentsci.1c00847 article EN cc-by ACS Central Science 2021-08-13

Luminescent covalent organic frameworks (LCOFs) have emerged as indispensable candidates in various applications due to their greater tunable emitting properties and structural robustness compared small molecule emitters. An unsolved issue this area is developing highly luminescent LCOFs of which the nonradiative quenching pathways were suppressed much possible. Here, a robust aminal-linked COF (DD-COF) possessing perdeuterated light-emitting monomers was designed synthesized. The...

10.1021/jacs.3c10511 article EN Journal of the American Chemical Society 2024-01-08

The major enteric RNA viruses in pigs include porcine epidemic diarrhoea virus (PEDV), transmissible gastroenteritis (TGEV), rotavirus A (PRV-A), kobuvirus (PKV), sapovirus (PSaV) and deltacoronavirus (PDCoV). For differential diagnosis, a multiplex RT-PCR method was established on the basis of N genes TGEV, PEDV PDCoV, VP7 gene PRV-A, polyprotein PKV PSaV. This could specifically detect PEDV, PSaV without cross-reaction to any other circulating Chinese pig farms. limit detection this as low...

10.1111/tbed.13385 article EN Transboundary and Emerging Diseases 2019-10-09

10.1016/s1003-6326(13)62523-6 article EN Transactions of Nonferrous Metals Society of China 2013-03-01

Contamination of 99TcO4–, a problematic radioactive anion in the nuclear fuel cycle, groundwater has been observed series legacy sites, representing notable radiation hazard and environmental concern. The development convenient, rapid, sensitive detection methods is therefore critical for radioactivity control remediation tasks. Traditional suffer from clear demerits either presence large interference coexisting species (e.g., counting methods) or requirement extensive instrumentation...

10.1021/acsami.0c01929 article EN ACS Applied Materials & Interfaces 2020-03-05

Bacterial infections seriously harm human health and cause many severe diseases, which triggered urgent demands to exploit specific sensitive biosensor strategies for Staphylococcus aureus detection. Here, a colorimetric photoelectrochemical dual-mode S. assay based on FePor-TPA was constructed. 2D thin film its bulk powder (FePor-TPA) were synthesized by in situ growth ITO solvothermal condition, respectively, both of exhibited excellent peroxidase-like catalase-like activity, originating...

10.1021/acs.analchem.3c01950 article EN Analytical Chemistry 2023-09-06

The removal of radioactive gaseous iodine is crucial for sustainable nuclear energy development, safe spent fuel management, and secure disposal waste medical waste. However, the efficient capture iodine, particularly methyl iodide, under conditions low concentration high-flow rate that are representative real-world scenarios remains underexplored. Herein, we adopted a "theory-first" strategy to design adsorbents with superior affinity iodide. rigorous theoretical calculations both...

10.1021/acscentsci.4c01318 article EN cc-by ACS Central Science 2024-10-25

Abstract Grouting is an important method to reinforce soft coal roadway, and the presence of primary cracks in body has influence on grouting effect. With discrete element simulation method, process seam was simulated. The mechanism revealed, while fracture characteristics pressure effect analyzed. results demonstrated that involves stages seepage, rapid splitting, slow stability. Due cracks, diffusion radius increased significantly. Under slurry pressure, tensile stress concentration formed...

10.1007/s40789-020-00404-2 article EN cc-by International Journal of Coal Science & Technology 2021-01-26

Dental pulp stem cells (DPSCs) and their exosomes (Exos) are effective treatments for regenerative medicine. Hypoxia was confirmed to improve the angiogenic potential of cells. However, effect mechanism hypoxia-preconditioned DPSC-Exos poorly understood. We isolated from DPSCs under normoxia (Nor-Exos) hypoxia (Hypo-Exos) added them human umbilical vein endothelial (HUVECs). HUVEC proliferation, migration capacity were assessed by CCK-8, transwell, tube formation assays, qRT-PCR Western...

10.3390/biom12040575 article EN cc-by Biomolecules 2022-04-14

Abstract Background Accurate identification of isolates belonging to genus Enterococcus, Streptococcus, coagulase-negative Staphylococcus, and Lactococcus at the species level is necessary provide a better understanding their pathogenic potential, aid in making clinical decisions, conduct epidemiologic investigations,especially when large blind samples must be analyzed. It useful simultaneously identify different genera using single primer pair. Methods We developed pair based on tuf gene...

10.1186/1476-0711-11-31 article EN cc-by Annals of Clinical Microbiology and Antimicrobials 2012-11-27

The development of biocompatible nanomaterials for smart drug delivery and bioimaging has attracted great interest in recent years biomedical fields. Here, the interaction between recently reported nitrogenated graphene (C 2 N) a prototypical protein (villin headpiece HP35) utilizing atomistic molecular dynamics simulations is studied. reveal that HP35 can form stable binding with C N monolayer. Although N–HP35 attractive interactions are constantly preserved, strength mild does not cause...

10.1002/smll.201603685 article EN Small 2017-01-31

Abstract Pancreatic cancer is one of the malignant tumors with worst prognosis, and 5‐year survival rate this disease less than 1%. About 90% pancreatic ductal adenocarcinoma (PDAC), targeting therapy has become a promising treatment for PDAC in recent years. To improve rate, novel therapeutic targets are still urgently needed. KIF18B was initially identified as member kinesin family involved multiple cellular processes, such separation chromosomes mitosis. Recently, it found that growth...

10.1002/jcp.29201 article EN Journal of Cellular Physiology 2019-12-26

In search of novel bioactive compounds with excellent and broad-spectrum antifungal activity nanopesticides sustained releasing property, a series myrtenal-based diacylhydrazines were designed, synthesized, characterized. The preliminary bioassay showed that 2-picolinyl hydrazide exhibited better or comparable than the commercial fungicides boscalid chlorothalonil against tested fungi. Furthermore, nanocellulose was designed as nanopesticide carrier prepared from two biomass materials,...

10.1021/acs.jafc.1c02694 article EN Journal of Agricultural and Food Chemistry 2021-10-29

The development of novel natural product-derived nano-pesticide systems with loading capacity and sustained releasing performance bioactive compounds is considered an effective promising plant protection strategy. In this work, 25

10.3390/ijms25094595 article EN International Journal of Molecular Sciences 2024-04-23

Abstract To explore novel natural product‐based nitrogen‐containing heterocyclic compounds with antiproliferative activity, 20 L ‐carvone‐derived pyrimidine‐urea 4a–4t were synthesized through the multi‐step reaction of ‐carvone, and structurally characterized by Fourier transform infrared (FT‐IR), hydrogen‐1 nuclear magnetic resonance ( 1 H‐NMR), Carbon‐13 13 C‐NMR), High‐resolution mass spectrometry (HRMS). Besides, in vitro activity target against HepG2, Hela, MCF‐7 cells was evaluated...

10.1002/jhet.4779 article EN Journal of Heterocyclic Chemistry 2024-01-09
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