A5059624803- Genetics and Neurodevelopmental Disorders
- Genetic Associations and Epidemiology
- Chemical Synthesis and Characterization
- Rheumatoid Arthritis Research and Therapies
- Heavy metals in environment
- Luminescence and Fluorescent Materials
- Molecular Sensors and Ion Detection
- Radioactive element chemistry and processing
- Cytokine Signaling Pathways and Interactions
- Nanoplatforms for cancer theranostics
- Covalent Organic Framework Applications
- Metal-Organic Frameworks: Synthesis and Applications
- Supramolecular Self-Assembly in Materials
- Adipokines, Inflammation, and Metabolic Diseases
- Genomic variations and chromosomal abnormalities
- Carbon and Quantum Dots Applications
- Arsenic contamination and mitigation
- Multiple Sclerosis Research Studies
- Systemic Lupus Erythematosus Research
- Adipose Tissue and Metabolism
- Advancements in Transdermal Drug Delivery
- Chromium effects and bioremediation
- Nanocluster Synthesis and Applications
- Gout, Hyperuricemia, Uric Acid
- Solid-state spectroscopy and crystallography
Soochow University
2023-2025
Chongqing University
2025
Central Hospital of Wuhan
2021-2025
National University of Singapore
2023-2025
Université Bourgogne Franche-Comté
2025
Southeast University
2023-2025
Sun Yat-sen University
2017-2025
Taizhou University
2023-2025
Huazhong University of Science and Technology
2021-2025
Chinese Academy of Agricultural Sciences
2022-2024
Obesity and associated metabolic diseases are characterized by a chronic low-grade inflammatory state with the infiltration of many cells, especially macrophages. Immune molecules, including some cytokines, have close relationship metabolism. Interleukin (IL)-25 is member IL-17 cytokine family that can regulate macrophages alleviate dysfunction; however, its role mechanisms in lipid metabolism remain to be extensively clarified. Human serum liver biopsy specimens, high-fat diet-induced...
Abstract Nucleolus, which participates in many crucial cellular activities, is an ideal target for evaluating the state of a cell or organism. Here, bright red‐emissive carbon dots (termed CPCDs) with excitation‐independent/polarity‐dependent fluorescence emission are synthesized by one‐step hydrothermal reaction between congo red and p ‐phenylenediamine. The CPCDs can achieve wash‐free, real‐time, long‐term, high‐quality nucleolus imaging live cells, as well vivo two common model...
As a critical radioactive anionic contaminant, traditional adsorbents primarily remove iodate (IO
Abstract Introduction Lower respiratory tract infections(LRTIs) in adults are complicated by diverse pathogens that challenge traditional detection methods, which often slow and insensitive. Metagenomic next-generation sequencing (mNGS) offers a comprehensive, high-throughput, unbiased approach to pathogen identification. This retrospective study evaluates the diagnostic efficacy of mNGS compared conventional microbiological testing (CMT) LRTIs, aiming enhance accuracy enable early clinical...
Abstract Objective To investigate all-cause and cause-specific mortality in SLE patients between two time periods, 1997–2005 2006–14. Methods We used an administrative health database from the province of British Columbia, Canada to match all incident 10 non-SLE individuals on sex, age index date. Cohorts were divided into subgroups, according diagnosis year: early cohort late The outcome was death [all-cause, renal disease, cancer, infection, cardiovascular disease (CVD) other]. Hazard...
Persistent luminescence nanoparticle scintillators (PLNS) have been attempted for X-ray-induced photodynamic therapy (X-PDT) because persistent after ceasing radiation can make PLNS use less cumulative irradiation time and dose to generate the same amount of reactive oxygen species (ROS) compared with conventional combat cancer cells. However, excessive surface defects in reduce efficiency quench luminescence, which is fatal efficacy X-PDT. Herein, SiO2@Zn2SiO4:Mn2+, Yb3+, Li+ was designed...
The removal of radioactive gaseous iodine is crucial for sustainable nuclear energy development, safe spent fuel management, and secure disposal waste medical waste. However, the efficient capture iodine, particularly methyl iodide, under conditions low concentration high-flow rate that are representative real-world scenarios remains underexplored. Herein, we adopted a "theory-first" strategy to design adsorbents with superior affinity iodide. rigorous theoretical calculations both...
The accumulation of M1-polarized macrophages and excessive inflammation are important in the pathogenesis diabetic foot ulcer (DFU). However, underlying mechanism DFU crucial regulators less well known. Our previous study reported that kallikrein-binding protein (KBP), an angiogenesis inhibitor, was significantly upregulated patients compared to its levels controls. effects KBP on monocyte chemotaxis macrophage M1 polarization were elucidated this study. Plasma counts assessed by ELISA flow...
To estimate the overall risk of venous thromboembolism (VTE), pulmonary embolism (PE) and deep vein thrombosis (DVT) among patients newly diagnosed with RA compared general population without RA; to trends VTE, PE DVT after diagnosis up 5 years population.Using previously validated case definition, we conducted a matched cohort study using population-based administrative health database from province British Columbia, Canada. We calculated incidence rates (IRs) fully adjusted hazard ratios...
Beige fat dissipates energy and functions as a defense against cold obesity, but the mechanism for its development is unclear. We found that interleukin (IL)-25 signaling through cognate receptor, IL-17 receptor B (IL-17RB), increased in adipose tissue after exposure β3-adrenoceptor agonist stimulation. IL-25 induced beige formation white (WAT) by releasing IL-4 IL-13 promoting alternative activation of macrophages regulate innervation up-regulate tyrosine hydroxylase (TH) up-regulation to...
Abstract Gram‐positive bacteria pose significant threats to human health, necessitating the development of targeted bacterial detection and eradication strategies. Nevertheless, current approaches often suffer from poor targeting specificity. Herein, study utilizes purple rice lixivium synthesize biomass carbon dots (termed BCDs) with wheat germ agglutinin‐like residues for precisely bacteria. Subsequently, fluorescein isothiocyanate (FITC) molecules are grafted onto BCDs yield FITC‐labeled...