- Food composition and properties
- Genomics and Rare Diseases
- Antimicrobial Peptides and Activities
- Microbial Metabolites in Food Biotechnology
- Polysaccharides Composition and Applications
- Genomics and Phylogenetic Studies
- Genomic variations and chromosomal abnormalities
- Autism Spectrum Disorder Research
- Nanoplatforms for cancer theranostics
- Meat and Animal Product Quality
- Antibiotic Resistance in Bacteria
- Neuroendocrine Tumor Research Advances
- Genetics and Neurodevelopmental Disorders
- Ovarian cancer diagnosis and treatment
- Bacteriophages and microbial interactions
- Intraperitoneal and Appendiceal Malignancies
- Animal Nutrition and Physiology
- Sparse and Compressive Sensing Techniques
- Nutritional Studies and Diet
- Gut microbiota and health
- Photoacoustic and Ultrasonic Imaging
- Aquaculture disease management and microbiota
- Probiotics and Fermented Foods
- Lung Cancer Treatments and Mutations
- Genetics, Aging, and Longevity in Model Organisms
Army Medical University
2001-2025
Zhejiang Cancer Hospital
2025
Guilin Medical University
2025
First Hospital of Jiaxing
2025
Jiaxing University
2025
Hangzhou Medical College
2025
Zhejiang Provincial People's Hospital
2025
Wenzhou Medical University
2008-2024
Xidian University
2023-2024
Jiangsu University
2014-2024
Abstract Enterogenic infection is a common complication for patients with radiation injury and requires efficient therapeutics in the clinic. Herein, we evaluated promising drug candidate T7E21RHD5, which peptide derived from intestinal Paneth cell-secreted human defensin 5. Oral administration of this alleviated diarrhea symptoms mice that received total abdominal irradiation (TAI, γ-ray, 12 Gy) improved survival. Pathologic analysis revealed T7E21RHD5 elicited an obvious mitigation...
More than thirty years of research exploring the link between corporate social responsibility (CSR) and financial performance (CFP) could not provide a satisfying resolution to tension exists economic objectives. In this paper, we have contributed existing CSR literature both theoretically empirically. On theoretical side, challenged assumption that managers consider all stakeholders equally important contend prioritize instead. We also extend agency theory by suggesting may actually reduce...
Ferroptosis-related genes have been reported to play important roles in many diseases, but their molecular mechanisms osteoporosis not elucidated. Based on two independent GEO datasets (GSE35956 and GSE35958), GSE35959 as the validation dataset, we comprehensively elucidated pathological mechanism of ferroptosis-related by GO analyses, KEGG analyses a PPI network. Then, We used Western Blot (WB) Quantitative real-time polymerase chain reaction (qPCR) verify expression level KMT2D, hub gene,...
Objective To develop a predictive model for microvascular invasion (MVI) in hepatocellular carcinoma (HCC) through radiomics analysis, integrating data from both enhanced computed tomography (CT) and magnetic resonance imaging (MRI). Methods A retrospective analysis was conducted on 93 HCC patients who underwent partial hepatectomy. The gold standard MVI based the histopathological diagnosis of tissue. were randomly divided into training validation groups 7:3 ratio. patients, including CT...
Gold nanorods (AuNRs) have been considered highly compelling materials for early cancer diagnosis and aroused a burgeoning fascination among the biomedical sectors. By leveraging versatile tunable optical properties of AuNRs, herein, we developed novel tumor-targeted dual-modal nanoprobe (FFA) that exhibits excellent bioluminescence photoacoustic imaging performance tumor diagnosis. FFA has synthesized by anchoring recombinant bioluminescent firefly luciferase protein (Fluc) on...
Genetic skeletal disorders (GSD) involving the system arises through disturbances in complex processes of development, growth and homeostasis remain a diagnostic challenge because their clinical heterogeneity genetic variety. Over past decades, tremendous effort platforms have been made to explore heterogeneity, massive new genes mutations identified different GSD, but information supplied by literature is still limited it hard meet further needs scientists clinicians. In this study,...
To investigate the mechanisms of multiple resistance and horizontal transfer genes in animal pathogens, we characterized molecular structures gene-related sequences a multidrug-resistant Klebsiella pneumoniae strain R46 isolated from rabbit. Molecular cloning was performed to clone genes, minimum inhibitory concentrations (MICs) were measured determine characteristics cloned related strains. A conjugation experiment conducted assess transferability plasmids. Sequencing comparative genomic...
De novo germline mutations (DNMs) are the rarest genetic variants proven to cause a considerable number of sporadic diseases, such as autism spectrum disorders, epileptic encephalopathy, schizophrenia, congenital heart disease, type 1 diabetes, and hearing loss. However, it is difficult accurately assess DNMs identify disease-causing genes from in probands. A common method this problem that harbor significantly more than expected by chance, with accurate background DNM rate (DNMR) required....
Due to inappropriate use, florfenicol resistance is becoming increasingly serious among animal respiratory tract and gut bacteria. To detect the mechanism Enterobacteriaceae bacteria, 292 isolates from feces were examined. The agar dilution method was conducted determine minimum inhibitory concentration (MIC) for florfenicol, polymerase chain reaction (PCR) performed genes. further explore molecular of resistance, whole-genome Leclercia adecarboxylata R25 sequenced. Of strains tested, 61.6%...
Abstract Objective evaluation methods for the elasticity, smoothness, and softness of cooked udon noodles were established on basis texture analysis. Noodles with different diameters amylose contents prepared to verify reliability proposed methods. Results revealed that elasticity could be examined by using method involved rinsing 10°C cold water 30 s stretching a single strand noodle at 3 mm/s an A/KIE probe until broken. The stiffness sample 3.5 mm determined indicate caused size dried...