- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Aortic Disease and Treatment Approaches
- Cardiovascular Function and Risk Factors
- Coronary Interventions and Diagnostics
- Cardiac Structural Anomalies and Repair
- Advanced MRI Techniques and Applications
- Antimicrobial Resistance in Staphylococcus
- Cardiac, Anesthesia and Surgical Outcomes
- Streptococcal Infections and Treatments
- Acute Myocardial Infarction Research
- Cardiomyopathy and Myosin Studies
- Atrial Fibrillation Management and Outcomes
- Ultrasound in Clinical Applications
- Cardiovascular Disease and Adiposity
- Phonocardiography and Auscultation Techniques
- Ultrasound and Hyperthermia Applications
- Medical Imaging Techniques and Applications
- Advanced X-ray and CT Imaging
- Orthopedic Infections and Treatments
- Kawasaki Disease and Coronary Complications
- Moyamoya disease diagnosis and treatment
- Cardiovascular Effects of Exercise
- Vascular Procedures and Complications
St Thomas' Hospital
2011-2024
Guy's and St Thomas' NHS Foundation Trust
2008-2022
University Hospital Centre Zagreb
2022
University of Zagreb
2022
Inserm
2022
Hôpital Dupuytren
2022
Lithuanian University of Health Sciences
2019-2022
Hôpitaux Universitaires Henri-Mondor
2019
Australian College of Critical Care Nurses
2017
Griffith University
2017
first two authors contributed equally.
To evaluate feasibility and outcome of Transoartic Transcatheter Sapien valve implantation.Transcatheter Aortic implantation (TAVI) using the Edwards SAPIEN device (Edwards LifeScience, Irvine, CA) is usually performed via transfemoral (TF) or transapical (TA) routes. Some patients are not suitable for these approaches. We report our experience with novel transaortic (TAo) approach a partial upper sternotomy discuss advantages future applications.Between January 2008 to March 2011 193 severe...
Transcatheter aortic valve implantation (TAVI) has demonstrated the feasibility of treating valvular heart disease with transcatheter therapy.On back this success, various concepts are being evaluated to treat other disease, especially mitral regurgitation (MR).The currently approved MR replicate surgical repair.However, most them cannot eliminate completely.Similar TAVI, a may provide valuable alternative.The FORTIS (Edwards Lifesciences, Irvine, CA, USA) is self-expanding device implanted...
We sought to evaluate the effects of significant coronary artery disease (CAD) upon outcome after transcatheter aortic valve implantation (TAVI).We performed a retrospective study 271 consecutive patients undergoing TAVI using either Edwards SAPIEN or XT valve. Pre-procedural angiograms were analysed by quantitative angiography (defining CAD as stenosis ≥70% ≥50% if in left main stem vein graft). Ninety-three out had CAD. There was no difference mortality at 30 days 12 months between two...
The aim of this study was to identify the incidence and risk factors for acute kidney injury (AKI) after TAVI, a potentially serious complication transcatheter aortic valve implantation (TAVI) that has been redefined by Valve Academic Research Consortium (VARC).We performed retrospective analysis 248 patients undergoing TAVI. AKI defined as VARC-modified Risk, Injury, Failure, Loss, End-stage (RIFLE) disease score ≥ 2. Eighty-nine suffered (35.9%) demonstrated increased mortality at 30 days...
Abstract Objective To evaluate changes in left ventricular mass and diastolic function during normal pregnancy. Methods This was a cross‐sectional study of 125 pregnant women at 9–42 weeks gestation 19 non‐pregnant female controls. Two‐dimensional M‐mode echocardiography the maternal ventricle atrium performed. Results During pregnancy increased by 52%. There an increase end‐diastolic end‐systolic diameters (12% 20%, respectively), posterior wall diameter diastole systole (22% 13%,...
Trans-catheter aortic valve implantation is rapidly becoming an established modality of treatment for patients with critical stenosis who are high risk conventional replacement. This approach also has its limitations; however, growing experience and improvements in the delivery system, it may be possible to overcome these limitations. We describe a case where trans-catheter approaches, that is, transfemoral or trans-apical using Edwards THV were not but successful was achieved through...
To identify the effects of preprocedural significant mitral regurgitation (MR) and change in MR severity upon mortality after transcatheter aortic valve implantation (TAVI) using Edwards SAPIEN system.A retrospective analysis 316 consecutive patients undergoing TAVI for stenosis at a single centre UK between March 2008 January 2013. Patients were stratified into two groups according to MR: ≥grade 3 classed as ≤grade 2 non-significant. Change was assessed by comparison baseline 30-day...
Abstract Background Work-related musculoskeletal pain (WRMSP) is increasingly recognised in cardiac ultrasound practice. WRMSP can impact workforce health, productivity and sustainability. We sought to investigate the prevalence, characteristics clinical of WRMSP. Methods Prospective electronic survey 157 echocardiographers 10 institutions. Data acquired on demographics, experience, working environment/pattern, location, severity pattern, professional, personal life career. Results 129/157...
To assess the potential of intravenous Optison, a second generation ultrasound contrast agent, and various imaging modes to determine myocardial, kidney, liver perfusion in normal subjects patients with left ventricular dysfunction or chronic pulmonary disease together renal hepatic dysfunction.Five 20 underwent grey scale echocardiographic myocardium, during 505 injections Optison. Images were assessed qualitatively by two independent observers quantitatively using video densitometry peak...
<h3>Background</h3> Discrepancies between the usual medications of patients and prescribed when are admitted to hospital could be associated with severe complications. Implementation medication reconciliation at admission has been reported as a way improve quality care. <h3>Purpose</h3> The aim study was evaluate feasibility additional contribution retroactive process in an acute cardiology unit. <h3>Material methods</h3> Before any intervention, we included prospectively, first part study,...
Real-time imaging is required to guide minimally invasive catheter-based cardiac interventions. While transesophageal echocardiography allows for high-quality visualization of anatomy, X-ray fluoroscopy provides excellent devices. We have developed a novel image fusion system that real-time integration 3-D and the fluoroscopy. The was validated in following two stages: 1) preclinical determine function validate accuracy; 2) clinical setting assess workflow feasibility overall accuracy. In...
Our goal was to establish normal values for quantitative color kinesis indexes of left ventricular (LV) wall motion over a wide range ages, which are required objective diagnosis regional systolic and diastolic dysfunction. Color-encoded images were obtained in 194 subjects (95 males, 99 females, age 2 mo 79 yr) four standard views. Quantitative magnitude timing function studied age- gender-related differences. Normal limits all ejection filling narrow (< or =25% the mean), with no major...