- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Cerebrovascular and Carotid Artery Diseases
- Ultrasound in Clinical Applications
- Cardiovascular Health and Disease Prevention
- Cardiac Structural Anomalies and Repair
- Ultrasound and Hyperthermia Applications
- Aortic Disease and Treatment Approaches
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Disease and Adiposity
- Acute Myocardial Infarction Research
- Pericarditis and Cardiac Tamponade
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac electrophysiology and arrhythmias
- Coronary Interventions and Diagnostics
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cardiovascular and Diving-Related Complications
- Photoacoustic and Ultrasonic Imaging
- Advanced MRI Techniques and Applications
- Cardiovascular Effects of Exercise
- Phonocardiography and Auscultation Techniques
- Cardiac pacing and defibrillation studies
University Hospital Southampton NHS Foundation Trust
2016-2025
British Cardiovascular Society
2021-2025
Southampton General Hospital
2015-2024
Essex Cardiothoracic Centre
2016-2024
Northwick Park Hospital
2012-2017
Royal Brompton Hospital
2011-2017
NIHR Royal Brompton Cardiovascular Biomedical Research Unit
2012-2017
Imperial College London
2012-2017
NIHR Imperial Biomedical Research Centre
2015-2017
Northwick Park Institute for Medical Research
2012-2016
Transcatheter aortic valve implantation (TAVI) is a less invasive alternative to surgical replacement and the treatment of choice for patients at high operative risk. The role TAVI in lower risk unclear.To determine whether noninferior surgery moderately increased risk.In this randomized clinical trial conducted 34 UK centers, 913 aged 70 years or older with severe, symptomatic stenosis due age comorbidity were enrolled between April 2014 2018 followed up through 2019.TAVI using any CE mark...
Atrial Fibrillation is the most common arrhythmia worldwide with a global age adjusted prevalence of 0.5% in 2010. Anticoagulation treatment using warfarin or direct oral anticoagulants effective reducing risk AF-related stroke by approximately two-thirds and can provide 10% reduction overall mortality. There has been increased interest detecting AF due to its incidence possibility prevent strokes. Inexpensive consumer devices which measure ECG may have potential accurately detect but do not...
The guideline provides a practical step-by-step guide in order to facilitate high-quality echocardiographic studies of patients with aortic stenosis. In addition, it addresses commonly encountered yet challenging clinical scenarios and covers the use advanced techniques, including TOE Dobutamine stress echocardiography assessment
The purpose of this document is to update the existing joint British Societies recommendations on multidisciplinary meetings (MDMs) published in 2015 reflect changes practice. We aim provide guidance structure and function MDMs which should be taking place every cardiac surgical centre. Out scope are that do not require routine presence a surgeon such as electrophysiology those provided centre, complex aortic surgery.
Background— Clinical assessment often cannot reliably or rapidly risk stratify patients hospitalized with suspected acute coronary syndrome. The real-world clinical value of stress echocardiography (SE) in these is unknown. Thus, we undertook this study to assess the feasibility, safety, ability for early triaging, and prediction hard events SE incorporated into a chest pain unit admitted pain, nondiagnostic ECG, negative 12-hour troponin. Methods Results— Accordingly, 839 consecutive who...
Exercise electrocardiography (ExECG) is widely used in suspected stable angina (SA) as the initial test for evaluation of coronary artery disease (CAD). We hypothesized that exercise stress echo (ESE) would be efficacious with cost advantage over ExECG when utilized test.
The Global Registry of Acute Coronary Events (GRACE) score was developed to evaluate risk in patients with the acute coronary syndrome or without ST-segment elevation. Little is known about its performance at predicting in-hospital mortality for ethnic minority patients.We identified 326 160 admissions non-ST-segment elevation myocardial infarction (NSTEMI) Myocardial Infarction National Audit Project (MINAP), 2010-17, including White (n = 299 184) and minorities (excluding minorities) 26...
To assess gender, ethnicity, and deprivation-based differences in provision of aortic valve replacement (AVR) England for adults with stenosis (AS).We retrospectively identified AS from the English Hospital Episode Statistics (HES) between April 2016 March 2019 those who subsequently had an AVR. We separately used HES-linked Clinical Practice Research Datalink (CPRD) to identify people AVR evaluate timeliness their procedure (CPRD-AVR cohort). ORs diagnosis were estimated using multivariable...
ABSTRACT Background In the aftermath of Covid19 pandemic and lockdowns, there has been a growing population awaiting transthoracic echocardiograms for potential valvular heart disease. Conducting comprehensive all individuals may no longer be practical, leading to substantial delays in obtaining necessary scans. This paper explores an alternative approach, suggesting consideration dedicated shorter scans specifically patients suspected having Hypothesis To address increasing waiting times...
Abstract Background Work-related musculoskeletal pain (WRMSP) is increasingly recognised in cardiac ultrasound practice. WRMSP can impact workforce health, productivity and sustainability. We sought to investigate the prevalence, characteristics clinical of WRMSP. Methods Prospective electronic survey 157 echocardiographers 10 institutions. Data acquired on demographics, experience, working environment/pattern, location, severity pattern, professional, personal life career. Results 129/157...
Arterial stiffness is thought to be a precursor atherosclerosis. Conventional arterial parameters as potential biomarkers of radiation-induced damage were investigated. Patients with head and neck cancer treated radiotherapy ≥2 years previously one side the included. The unirradiated was internal control. Beta index (B) elastic modulus ( Ep) used assess measured in proximal, mid, distal common carotid artery (CCA) compared corresponding segments. Fifty patients (68% male; median age 58...
We report a case of Takotsubo syndrome occurring in the recovery phase after dobutamine stress echocardiogram. is widely acknowledged cause reversible left ventricular systolic dysfunction. It has garnered much attention from cardiological community since its presentation frequently mimics that ST-segment elevation myocardial infarction. The exact aetiology remains incompletely defined, although recognized as precipitating factor. In recent years it emerged testing, part patient's...
The authors recently demonstrated that simultaneous assessment of myocardial perfusion (MP) and wall motion (WM) by contrast echocardiography (MCE) is feasible accurate when incorporated into a clinical stress (SE) service. However, it unknown whether the incremental prognostic value MP beyond WM, previously shown in research studies, reproducible MCE performed arena.In this prospective study, was multiple operators during routine SE, whose results were classified as normal WM MP, abnormal...
<h3>Objective</h3> Non-invasive cardiac imaging may suffer from poor image quality in morbidly obese individuals. This study aimed to determine the clinical value of contemporary stress echocardiography (SE) patients referred for assessment suspected coronary artery disease (CAD). <h3>Methods</h3> prospective, multicentre observational was conducted two district hospitals and one tertiary centre London, UK. Individuals with body mass index ≥35 kg/m<sup>2</sup> SE were evaluated. The...